Catalog No.
YHE38501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Arg325
Predicted molecular weight
38.40 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P42898
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Methylenetetrahydrofolate reductase, MTHFR
Hypercoagulability and the A1298C MTHFR Mutation: Case Series of Unexplained Pulmonary Embolism., PMID:40453635
Pharmacogenetic Profiling of Genes Associated with Outcomes of Chemotherapy in Omani Healthy Controls., PMID:40428413
Multiple Hits on Cerebral Folate, Tetrahydrobiopterin and Dopamine Metabolism in the Pathophysiology of Parkinson's Disorder: A Limited Study of Post-Mortem Human Brain Tissues., PMID:40422884
Colorimetric loop-mediated isothermal amplification (cLAMP) assay for the genotyping of a thrombophilia genetic risk factor, MTHFR (C677T)., PMID:40392249
Genetic polymorphisms in folate metabolism and their association with recurrent spontaneous abortion., PMID:40389352
Exploring the therapeutic efficacy of Bai-Shao in mitigating comorbid epileptic seizures and cognitive impairment via inflammatory signaling pathways: insights from in silico and in vivo studies., PMID:40386636
Safety and Efficacy of High-Dose Folinic Acid in Children with Autism: The Impact of Folate Metabolism Gene Polymorphisms., PMID:40362912
Determining the Risk of Type 2 Diabetes for rs1801133 Genotypes in Multiethnic Populations: A Global Meta-Epidemiological Study., PMID:40362226
[New Genetic Variants Involved in the Pathogenesis of Autosomal Dominant Alport Syndrome: A Familial Case Report]., PMID:40332975
Factors associated with hyperhomocysteinemia in relatively healthy adult males in northern Shaanxi, China: A cross-sectional study., PMID:40324235
Study on MTHFR (C677T & A1298C) Gene Polymorphisms in the Condition of Glucose Intolerance During Pregnancy., PMID:40317814
The Role of Folic Acid in DNA Methylation and Breast Cancer., PMID:40298153
Contribution of Methylenetetrahydrofolate Reductase Genotypes to Brain Tumor Risk Determination in Taiwan., PMID:40295056
Association of MTHFR and DNMT-1 Gene Polymorphisms with Acute Coronary Syndrome in Patients Admitted to the Emergency Department., PMID:40283597
MTHFR Gene Polymorphisms: A Single Gene with Wide-Ranging Clinical Implications-A Review., PMID:40282401
Xenobiotic metabolizing gene variants and the risk of male infertility - A systematic review, meta-analysis and in silico analysis., PMID:40271533
Association of MTHFR Gene with Type 2 Diabetes Mellitus: A Case-Control Study and Meta-Analysis., PMID:40258351
Relationship between MTHFR, MTRR gene polymorphisms and H-type hypertension: a systematic review and meta-analysis., PMID:40256868
Hyperhomocysteinemia in Takayasu arteritis-genetically defined or burden of the proinflammatory state?, PMID:40255391
Relationship between MTHFR 677C > T polymorphism and serum PIVKA-II levels in hepatocellular carcinoma., PMID:40243201
Appraising the causal relevance of maternal red blood cell folate and congenital heart disease in offspring: 2-sample Mendelian randomization., PMID:40233869
Pharmacogenomics in pediatric oncology patients with solid tumors related to chemotherapy-induced toxicity: A systematic review., PMID:40222694
Association of MTHFR missense variants with thromboembolic diseases and coagulation factor levels in European populations., PMID:40200264
Genetic variants associated with idiopathic Parkinson's disease in Latin America: A systematic review., PMID:40178685
Prevalence of MTHFR C677T polymorphism and its association with serum homocysteine and blood pressure among different ethnic groups: insights from a cohort study of Nepal., PMID:40158176
Comprehensive review of thrombophilia: pathophysiology, prevalence, risk factors, and molecular diagnosis., PMID:40157494
An Allele of the MTHFR one-carbon metabolism gene predicts severity of COVID-19., PMID:40093216
Inherited thrombophilias and stillbirth: a systematic review and meta- analysis., PMID:40087172
Evaluating the Effect of Epigallocatechin Gallate (EGCG) in Reducing Folate Levels in Reproductive Aged Women by MTHFR and DHFR Genotype in Combination With Letrozole or Clomiphene., PMID:40077973
Relationship between IgA vasculitis and prothrombotic risk factors: A prospective, case-control study., PMID:40060137
A Case of Acute Renal Infarct Secondary to Protein S Deficiency., PMID:40060068
Impaired folate metabolism reshapes auditory response profiles and impairs loudness perception in MTHFR-deficient mice., PMID:40057124
Indications of the SERPINE 1 variant rs1799768's role in anti-VEGF therapy resistance in neovascular age-related macular degeneration., PMID:40048436
Global and population-specific association of MTHFR polymorphisms with preterm birth risk: a consolidated analysis of 44 studies., PMID:40025425
The complex role of glycine N-methyltransferase in metabolism-a review., PMID:40025311
Discovery of a distinct type of methylenetetrahydrofolate reductase family that couples with tetrahydrofolate-dependent demethylases., PMID:40016375
The Relationship Between Thrombophilia and Modifications in First-Trimester Prenatal Screening Markers., PMID:40005435
The impact of genetic variations in FPGS , MTHFR , and ATIC on methotrexate response among pediatric patients with acute lymphoblastic leukemia., PMID:39991907
Functional Evaluation of Neural Tube Defect-Related Missense Mutations Using In Silico Methods., PMID:39950581
The impact of MTHFR and VDR polymorphisms on endometriosis susceptibility: Insights from a systematic review and meta-analysis., PMID:39946760
Ocular Biometry and Genomic Association in Primary Angle Closure Disease. A Descriptive study., PMID:39936063
[The role of genetic polymorphisms in folate metabolism genes in the manifestation of migraine in children]., PMID:39930676
Association of methylenetetrahydrofolate reductase (MTHFR) C677T, MTHFR A1298C, and CYP3A4 A290G gene polymorphisms with clinical outcomes of HLA-matched sibling allogeneic hematopoietic cell transplantation in an Egyptian patient/donor cohort., PMID:39913956
5,10-methylenetetrahydrofolate reductase C677T gene polymorphism as a risk factor for premature coronary artery disease in patients with type 2 diabetes mellitus., PMID:39911235
Meta Analysis of Methylenetetrahydrofolate Reductase (MTHFR) C677T polymorphism and its association with folate and colorectal cancer., PMID:39875876
Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms are associated with major depressive disorder in the Saudi patients attending Erada complex for mental health and Erada services - Jeddah, Saudi Arabia., PMID:39871098
The Inhibitory Effects of NCT503 and Exogenous Serine on High-Selenium Induced Insulin Resistance in Mice., PMID:39861441
Novel p.Arg534del Mutation and MTHFR C667T Polymorphism in Fragile X Syndrome (FXS) With Autism Spectrum Phenotype: A Case Report., PMID:39839505
Pharmacogenetic Testing in Treatment-resistant Panic Disorder: a Preliminary Analysis., PMID:39839219
For research use only. Not for human or drug use.
