Catalog No.
YHE36701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ile234-Phe491
Predicted molecular weight
32.18 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P42685
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PTK5, RAK, Tyrosine-protein kinase FRK, Nuclear tyrosine protein kinase RAK, Protein-tyrosine kinase 5, FYN-related kinase, FRK
The wheat fructokinase gene TaFRK2-7B1 positively regulates grain size by modulating fructose metabolism., PMID:40473157
Development and validation of a kinase-related gene signature as a novel diagnostic and prognostic model for prostate cancer., PMID:39965532
FRK exerts oncogenic effects by targeting NQO2 via exosomal miR-9-3p to regulate mitochondrial function., PMID:39625368
Exogenous methyl jasmonate (MeJA) mediated carbohydrate metabolism in apple fruit during ripening., PMID:39603033
Ubiquitin-related gene markers predict immunotherapy response and prognosis in patients with epithelial ovarian carcinoma., PMID:39448713
Systemic ALK-negative anaplastic large cell lymphoma: Insights into morphologic, immunophenotypic, genetic and molecular characteristics., PMID:39424106
Tau pathology in the dorsal raphe may be a prodromal indicator of Alzheimer's disease., PMID:39143322
The BCR::ABL1 tyrosine kinase inhibitors ponatinib and nilotinib differentially affect endothelial angiogenesis and signalling., PMID:39009935
M1-type microglia-derived exosomes contribute to blood-brain barrier damage., PMID:38588846
Intracellular C3 protects β-cells from IL-1β-driven cytotoxicity via interaction with Fyn-related kinase., PMID:38346191
Protein profile analysis of tension wood development in response to artificial bending and gravitational stimuli in Betula platyphylla., PMID:38122834
A computationally designed antigen eliciting broad humoral responses against SARS-CoV-2 and related sarbecoviruses., PMID:37749309
Polypharmacology-based kinome screen identifies new regulators of KSHV reactivation., PMID:37669313
Characteristics of mesenchymal stem cells and their exosomes derived from giant panda (Ailuropoda melanoleuca) endometrium., PMID:37639049
The transport of mannitol in Sinorhizobium meliloti is carried out by a broad-substrate polyol transporter SmoEFGK and is affected by the ability to transport and metabolize fructose., PMID:37505890
A missense mutation in the C. elegans src-2 tyrosine-protein kinase reduces brood size and enhances embryonic morphogenesis defects in src-1(RNAi) conditions., PMID:37497183
Comprehensive Analysis of Prognostic Value and Immune Infiltration of Src Family Kinases in Hepatocellular Carcinoma., PMID:37258470
Identification of prognostic hub genes and therapeutic targets for selenium deficiency in chicks model through transcriptome profiling., PMID:37248251
Effectiveness of Fortified Mid-Day Meal in Reducing Anemia Among School Children in Dhenkanal, Odisha: A Quasi-Experimental Study., PMID:37165677
Polypharmacology-based kinome screen identifies new regulators of KSHV reactivation., PMID:36778430
Little discrepancy between one-stage and chromogenic factor VIII (FVIII)/IX assays in a large international cohort of persons with nonsevere hemophilia A and B., PMID:36696222
New Fructokinase, OsFRK3, Regulates Starch Accumulation and Grain Filling in Rice., PMID:36595531
Calcyclin-binding protein-promoted degradation of MdFRUCTOKINASE2 regulates sugar homeostasis in apple., PMID:36461944
An ErbB Lineage Co-Regulon Harbors Potentially Co-Druggable Targets for Multimodal Precision Therapy in Head and Neck Squamous Cell Carcinoma., PMID:36362284
WGCNA combined with GSVA to explore biomarkers of refractory neocortical epilepsy., PMID:36247523
Hydrolysis of Soybean Milk Protein by Papain: Antioxidant, Anti-Angiotensin, Antigenic and Digestibility Perspectives., PMID:36134964
Hemifacial microsomia is linked to a rare homozygous variant V162I in FRK and validated in zebrafish., PMID:36070195
Discovery of an Orally Bioavailable and Selective PKMYT1 Inhibitor, RP-6306., PMID:35880755
FRK inhibits glioblastoma progression via phosphorylating YAP and inducing its ubiquitylation and degradation by Siah1., PMID:35723276
Identification and relative expression analysis of CaFRK gene family in pepper., PMID:35646505
Joint status of patients with nonsevere hemophilia A., PMID:35171522
Genetic variants associated with circulating C-reactive protein levels and colorectal cancer survival: Sex-specific and lifestyle factors specific associations., PMID:34888857
HIV-1 Vif suppresses antiviral immunity by targeting STING., PMID:34811497
AhABI4s Negatively Regulate Salt-Stress Response in Peanut., PMID:34721468
Genome-wide identification of FRK genes in Populus trichocarpa and their expression under different nitrogen treatments., PMID:34616114
Oral delivery of systemic monoclonal antibodies, peptides and small molecules using gastric auto-injectors., PMID:34462588
TRIM44 facilitates ovarian cancer proliferation, migration, and invasion by inhibiting FRK., PMID:34034495
Individuals Diagnosed with Binge-Eating Disorder Have DNA Hypomethylated Sites in Genes of the Metabolic System: A Pilot Study., PMID:33922358
Systematic screening identifies therapeutic antisense oligonucleotides for Hutchinson-Gilford progeria syndrome., PMID:33707772
A predominant isoform of fructokinase, HbFRK2, is involved in Hevea brasiliensis (para rubber tree) latex yield and regeneration., PMID:33706182
Phase 3 Trials of Tirbanibulin Ointment for Actinic Keratosis., PMID:33567191
Exosomes derived from hypoxic glioma deliver miR-1246 and miR-10b-5p to normoxic glioma cells to promote migration and invasion., PMID:33446893
Identification of genes associated with soluble sugar and organic acid accumulation in 'Huapi' kumquat (Fortunella crassifolia Swingle) via transcriptome analysis., PMID:33417244
GATA6 activated long non-coding RNA PCAT1 maintains stemness of non-small cell lung cancer by mediating FRK., PMID:33277858
Emerging Kinase Therapeutic Targets in Pancreatic Ductal Adenocarcinoma and Pancreatic Cancer Desmoplasia., PMID:33233470
Kinome Array Profiling of Patient-Derived Pancreatic Ductal Adenocarcinoma Identifies Differentially Active Protein Tyrosine Kinases., PMID:33213062
The novel peptide NbPPI1 identified from Nicotiana benthamiana triggers immune responses and enhances resistance against Phytophthora pathogens., PMID:33205861
Loss of progesterone receptor is associated with distinct tyrosine kinase profiles in breast cancer., PMID:32710281
Post-hoc analysis of single nucleotide polymorphism profile for eyes with vascularized pigment epithelial detachment due to ARMD., PMID:32578437
For research use only. Not for human or drug use.
