Catalog No.
YHE30401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr189-Asn405
Predicted molecular weight
27.01 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P41218
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Myeloid cell nuclear differentiation antigen, MNDA
The dual roles of human PYHIN family proteins in cancer: mechanisms and therapeutic implications., PMID:40386782
Efficacy and safety of low-dose IL-2 as an add-on therapy to riluzole (MIROCALS): a phase 2b, double-blind, randomised, placebo-controlled trial., PMID:40354799
Identification and validation of palmitoylation-related biomarkers in gestational diabetes mellitus., PMID:40055514
A bacterial artificial chromosome mouse model of amyotrophic lateral sclerosis manifests 'space cadet syndrome' on two FVB backgrounds., PMID:39945358
Amyotrophic lateral sclerosis caused by FUS mutations: advances with broad implications., PMID:39862884
Elevated Cerebrospinal Fluid Ubiquitin Carboxyl-Terminal Hydrolase Isozyme L1 in Asymptomatic C9orf72 Hexanucleotide Repeat Expansion Carriers., PMID:39548852
Meta-Analysis and DIA-MS-Based Proteomic Investigation of COPD Patients and Asymptomatic Smokers in the Indian Population., PMID:39436829
The Effect of Vitamin D Deficiency on Immune-Related Hub Genes: A Network Analysis Associated With Type 1 Diabetes., PMID:39371824
Identification and validation of hub differential genes in pulmonary sarcoidosis., PMID:39364409
Site-discordant expression of myeloid cell nuclear differentiation antigen in blastic plasmacytoid dendritic cell neoplasm., PMID:39303672
Apolipoproteins, lipids, lipid-lowering drugs and risk of amyotrophic lateral sclerosis and frontotemporal dementia: a meta-analysis and Mendelian randomisation study., PMID:39230722
RAN Translation of C9orf72-Related Dipeptide Repeat Proteins in Zebrafish Recapitulates Hallmarks of Amyotrophic Lateral Sclerosis and Identifies Hypothermia as a Therapeutic Strategy., PMID:39215697
SETDB1 suppresses NK cell-mediated immunosurveillance in acute myeloid leukemia with granulo-monocytic differentiation., PMID:39096901
Truncated tau interferes with the autophagy and endolysosomal pathway and results in lipid accumulation., PMID:39009859
Annexin A11 mutations are associated with nuclear envelope dysfunction in vivo and in human tissues., PMID:38989900
Myeloid cell-expressed MNDA enhances M2 polarization to facilitate the metastasis of hepatocellular carcinoma., PMID:38904028
Genotypes and phenotypes of motor neuron disease: an update of the genetic landscape in Scotland., PMID:38852112
Mutations in the tail and rod domains of the neurofilament heavy-chain gene increase the risk of ALS., PMID:38775181
An ALS-associated mutation dysregulates microglia-derived extracellular microRNAs in a sex-specific manner., PMID:38721655
MNDA, a PYHIN factor involved in transcriptional regulation and apoptosis control in leukocytes., PMID:38680493
MNDA expression and its value in differential diagnosis of B-cell non-Hodgkin lymphomas: a comprehensive analysis of a large series of 1293 cases., PMID:38627702
Low TYROBP expression predicts poor prognosis in multiple myeloma., PMID:38549127
Unveiling Shared Immune Responses in Porcine Alveolar Macrophages during ASFV and PRRSV Infection Using Single-Cell RNA-seq., PMID:38543614
Identifying Biomarkers and Therapeutic Targets by Multiomic Analysis for HNSCC: Precision Medicine and Healthcare Management., PMID:38524437
Single-Molecule Characterization and Super-Resolution Imaging of Alzheimer's Disease-Relevant Tau Aggregates in Human Samples., PMID:38523073
Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD., PMID:38277467
Identification of shared pathogenetic mechanisms between COVID-19 and IC through bioinformatics and system biology., PMID:38267482
Study on Potential Differentially Expressed Genes in Idiopathic Pulmonary Fibrosis by Bioinformatics and Next-Generation Sequencing Data Analysis., PMID:38137330
Exploration of the biomarkers of comorbidity of psoriasis with inflammatory bowel disease and their association with immune infiltration., PMID:38115636
Data-independent acquisition proteomics of cerebrospinal fluid implicates endoplasmic reticulum and inflammatory mechanisms in amyotrophic lateral sclerosis., PMID:38087504
Scaling of an antibody validation procedure enables quantification of antibody performance in major research applications., PMID:37995198
Bioinformatics analyses of potentially common pathogenic networks for primary Sjögren's syndrome complicated with acute myocardial infarction., PMID:37935719
Identification of Genes and Key Pathways Associated with the Pathophysiology of Lung Cancer and Atrial Fibrillation., PMID:37883760
Roadmap for C9ORF72 in Frontotemporal Dementia and Amyotrophic Lateral Sclerosis: Report on the C9ORF72 FTD/ALS Summit., PMID:37847372
Hypoxia-induced transcriptional stress is mediated by ROS-induced R-loops., PMID:37843099
Bioinformatics analysis of copper death gene in diabetic immune infiltration., PMID:37773841
Mutation in the FUS nuclear localisation signal domain causes neurodevelopmental and systemic metabolic alterations., PMID:37772684
C9orf72-ALS human iPSC microglia are pro-inflammatory and toxic to co-cultured motor neurons via MMP9., PMID:37736756
Uncovering the pathogenesis of obesity complicated with papillary thyroid carcinoma via bioinformatics and experimental validation., PMID:37671970
Synaptic expression of TAR-DNA-binding protein 43 in the mouse spinal cord determined using super-resolution microscopy., PMID:37671010
The identification of high-performing antibodies for Charged multivesicular body protein 2b for use in Western Blot, immunoprecipitation and immunofluorescence., PMID:37635943
Optogenetic cleavage of the Miro GTPase reveals the direct consequences of real-time loss of function in Drosophila., PMID:37590319
The identification of high-performing antibodies for Profilin-1 for use in Western blot, immunoprecipitation and immunofluorescence., PMID:37576538
The identification of high-performing antibodies for transmembrane protein 106B (TMEM106B) for use in Western blot, immunoprecipitation, and immunofluorescence., PMID:37545650
Yeast NDI1 reconfigures neuronal metabolism and prevents the unfolded protein response in mitochondrial complex I deficiency., PMID:37399212
Scaling of an antibody validation procedure enables quantification of antibody performance in major research applications., PMID:37398479
The identification of high-performing antibodies for RNA-binding protein FUS for use in Western Blot, immunoprecipitation, and immunofluorescence., PMID:37384305
The identification of high-performing antibodies for TDP-43 for use in Western Blot, immunoprecipitation and immunofluorescence., PMID:37359785
The identification of high-preforming antibodies for Ubiquilin-2 for use in Western Blot, immunoprecipitation, and immunofluorescence., PMID:37359784
Structural mechanism of dsDNA recognition by the hMNDA HIN domain: New insights into the DNA-binding model of a PYHIN protein., PMID:37348588