Catalog No.
YHE25001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Ala477
Predicted molecular weight
55.13 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P40123
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Adenylyl cyclase-associated protein 2, CAP 2, CAP2
A Cyclic Peptide-Based Radiotheranostic Agent for Urokinase-Type Plasminogen Activator in Tumors., PMID:40100321
Nonlinear mixed-effects models to analyze actin dynamics in dendritic spines., PMID:39962126
Exploring the Mechanism of Clostridium autoethanogenum Protein for Broiler Growth Based on Gut Microbiota and Serum Metabolomics., PMID:39857260
Identification and Immunological Characterization of Cuproptosis Related Genes in Preeclampsia Using Bioinformatics Analysis and Machine Learning., PMID:39853851
Integrative machine learning frameworks to uncover specific protein signature in neuroendocrine cervical carcinoma., PMID:39794740
Identification of CAP genes in finger lime (Citrus australasica) and their role in plant responses to abiotic and biotic stress., PMID:39632943
Efficacy comparison in cap VLPs of PCV2 and PCV3 as swine vaccine vehicle., PMID:39173309
Cyclase-associated protein (CAP) inhibits inverted formin 2 (INF2) to induce dendritic spine maturation., PMID:39154297
Sequential window acquisition of all theoretical mass spectra (SWATH-MS) as an emerging proteomics approach for the discovery of dark-cutting beef biomarkers., PMID:39096797
An essential role for Cmtr2 in mammalian embryonic development., PMID:39094818
Structural and functional characterization of the bacterial Cap3 enzyme in deconjugation and regulation of the cyclic dinucleotide transferase CD-NTase., PMID:38968768
CAP2 contributes to Parkinson's disease diagnosed by neutrophil extracellular trap-related immune activity., PMID:38846945
The actin-binding protein CAP1 represses MRTF-SRF-dependent gene expression in mouse cerebral cortex., PMID:38713765
Reversible conjugation of a CBASS nucleotide cyclase regulates bacterial immune response to phage infection., PMID:38589469
Evaluation of Clostridium autoethanogenum protein as a new protein source for broiler chickens in replacement of soybean meal., PMID:38575131
Construction and validation of a joint diagnosis model based on random forest and artificial intelligence network for hepatitis B-related hepatocellular carcinoma., PMID:38482416
A comparative evaluation of the analytical performances of premier resolution-high-performance liquid chromatography (PR-HPLC) with capillary zone electrophoresis (CZE) assays for the detection of hemoglobin variants and the quantitation of HbA0, A2, E, and F., PMID:38197862
Expression of a SAG protein with a CAP domain from Eimeria necatrix and its role in invasion and immunoprotection., PMID:37931477
Cyclase-associated protein interacts with actin filament barbed ends to promote depolymerization and formin displacement., PMID:37863260
CAP2 promotes gastric cancer metastasis by mediating the interaction between tumor cells and tumor-associated macrophages., PMID:37707957
An association study of cyclase-associated protein 2 and frailty., PMID:37537790
Essential roles of RNA cap-proximal ribose methylation in mammalian embryonic development and fertility., PMID:37436893
Inhibition of Infectious HIV-1 Production by Rerouting the Cellular Furin Inhibitor Serpin B8., PMID:37272794
Ubiquitin-like conjugation by bacterial cGAS enhances anti-phage defence., PMID:36848932
An E1-E2 fusion protein primes antiviral immune signalling in bacteria., PMID:36755092
Evolutionary tuning of barbed end competition allows simultaneous construction of architecturally distinct actin structures., PMID:36729023
mRNA ageing shapes the Cap2 methylome in mammalian mRNA., PMID:36725932
miRNA mediated downregulation of cyclase-associated protein 1 (CAP1) is required for myoblast fusion., PMID:36246999
Identification of genetic molecular markers and immune infiltration characteristics of Alzheimer's disease through weighted gene co-expression network analysis., PMID:36071897
2'-O-Methylation of the second transcribed nucleotide within the mRNA 5' cap impacts the protein production level in a cell-specific manner and contributes to RNA immune evasion., PMID:36018811
Investigation of differentially expressed genes and dysregulated pathways involved in multiple sclerosis., PMID:35871892
A loosened gating mechanism of RIG-I leads to autoimmune disorders., PMID:35580046
Multiple Molecular Dynamics Simulations and Energy Analysis Unravel the Dynamic Properties and Binding Mechanism of Mutants HIV-1 Protease with DRV and CA-p2., PMID:35319278
ENaC activation by proteases., PMID:35276025
Analysis of mRNA and Protein Levels of CAP2, DLG1 and ADAM10 Genes in Post-Mortem Brain of Schizophrenia, Parkinson's and Alzheimer's Disease Patients., PMID:35163460
Disease association of cyclase-associated protein (CAP): Lessons from gene-targeted mice and human genetic studies., PMID:35150966
A homozygous CAP2 pathogenic variant in a neonate presenting with rapidly progressive cardiomyopathy and nemaline rods., PMID:34862840
Expression of ovine CTNNA3 and CAP2 genes and their association with growth traits., PMID:34481004
Endoplasmic Reticulum Stress Induces CAP2 Expression Promoting Epithelial-Mesenchymal Transition in Liver Cancer Cells., PMID:34294609
Redefining actin dynamics of the pointed-end complex in striated muscle., PMID:34266732
Functional Redundancy of Cyclase-Associated Proteins CAP1 and CAP2 in Differentiating Neurons., PMID:34204261
Interplay between transcriptional regulators and the SAGA chromatin modifying complex fine-tune iron homeostasis., PMID:33933457
Identification of hub genes related to the progression of type 1 diabetes by computational analysis., PMID:33827531
CAP2 is a regulator of actin pointed end dynamics and myofibrillogenesis in cardiac muscle., PMID:33742108
Cyclase-associated protein 2 (CAP2) controls MRTF-A localization and SRF activity in mouse embryonic fibroblasts., PMID:33637797
Mouse Ifit1b is a cap1-RNA-binding protein that inhibits mouse coronavirus translation and is regulated by complexing with Ifit1c., PMID:33454014
Upregulation of cyclase-associated actin cytoskeleton regulatory protein 2 in epithelial ovarian cancer correlates with aggressive histologic types and worse outcomes., PMID:32211793
Effects of Heat stress and molecular mitigation approaches in orphan legume, Chickpea., PMID:32133603
Prognostic impact of adenylyl cyclase-associated protein 2 (CAP2) in glioma: A clinicopathological study., PMID:32042970
Regulation of INF2-mediated actin polymerization through site-specific lysine acetylation of actin itself., PMID:31871199
For research use only. Not for human or drug use.
