Catalog No.
YHE23901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
His1572-Lys1754
Predicted molecular weight
22.41 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P39060
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NC1, COL18A1, Collagen alpha-1(XVIII) chain
Integrated transcriptomic and immune profiling reveals crucial molecular pathways and hub genes associated with postoperative delirium in elderly patients., PMID:40417694
Sintilimab + Nab-PP Combined with Recombinant Human Vascular Endothelial Inhibitor for Locally Advanced/Advanced and Recurrent Metastatic Squamous Non-Small Cell Lung Cancer: Study Protocol for a Single-Arm, Multi-Centre Phase II Clinical Study., PMID:40415559
Inhibitory effect of Endostar on HIF-1 with upregulation of MHC-I in lung cancer cells., PMID:40392714
Chinese Family With Knobloch Syndrome Associated With a Novel PAK2 Variant Leading to Reduced Phosphorylation Levels., PMID:40247748
Recombinant Human Endostatin Suppressed the Biological Behavior of Human Umbilical Vein Endothelial Cells Under Hypoxic and Hypoxic/Starvation Conditions In Vitro., PMID:40196419
Layer-specific molecular signatures of colon anastomotic healing and leakage in mice., PMID:40169980
Large-Scale Plasma Proteomics to Profile Pathways and Prognosis of Chronic Pain., PMID:40048323
Prognostic value of prognostic nutritional index in patients with nasopharyngeal carcinoma treated with endostar and concurrent chemoradiotherapy., PMID:40011250
Antenatal phenotype associated with PAK2 pathogenic variants: bilateral pleural effusion as a warning sign., PMID:39994693
Safety of Endostar in combination with chemotherapy in patients with cancer., PMID:39960696
Study on PD-1 inhibitor combined with recombinant human endostatin and chemotherapy followed by IMRT in the treatment of advanced NSCLC., PMID:39928822
Potential Functions and Causal Associations of GNLY in Primary Open-Angle Glaucoma: Integration of Blood-Derived Proteome, Transcriptome, and Experimental Verification., PMID:39802509
Association between endostatin and mortality in patients with acute dyspnoea, with or without congestive heart failure: a single-centre, prospective, observational study., PMID:39800400
Suppressing the progression of bladder cancer using cyclovirobuxine D based on network pharmacology and bioinformatics approaches., PMID:39797986
Endostatin as a biomarker of systemic sclerosis: insights from a systematic review and meta-analysis., PMID:39763677
Comparative transcriptome analysis of albino northern snakehead (Channa argus) reveals its various collagen-related DEGs in caudal fin cells., PMID:39739744
Endostatin in disease modulation: From cancer to beyond., PMID:39708990
Endostatin-expressing endometrial mesenchymal stem cells inhibit angiogenesis in endometriosis through the miRNA-21-5p/TIMP3/PI3K/Akt/mTOR pathway., PMID:39589222
Clinical and Molecular Findings in Patients with Knobloch Syndrome 1: Case Series Report., PMID:39457419
[Tujia medicine Toddalia asiatica improves synovial pannus in rats with collagen-induced arthritis through the PI3K/Akt signaling pathway]., PMID:39276054
Structural Insights into Endostatin-Heparan Sulfate Interactions Using Modeling Approaches., PMID:39274888
Gut microbiome influences efficacy of Endostatin combined with PD-1 blockade against colorectal cancer., PMID:39251538
Equivalency of Multiple Biomarkers to Clinical Pulmonary Arterial Hypertension Survival Risk Models., PMID:39154795
Osteoporosis in Relation to a Bone-Related Aging Biomarker Derived from the Urinary Proteomic Profile: A Population Study., PMID:39122459
Real-world effectiveness and safety of recombinant human endostatin plus PD-1 inhibitors and chemotherapy as first-line treatment for EGFR/ALK-negative, advanced or metastatic non-small cell lung cancer., PMID:39112947
Comparative Transcriptome Analysis of the Hypothalamic-Pituitary-Gonadal Axis of Jinhu Grouper (Epinephelus fuscoguttatus ♀ × Epinephelus tukula ♂) and Tiger Grouper (Epinephelus fuscoguttatus)., PMID:39062708
Efficacy and Safety Analysis of Recombinant Human Endostatin (Endostar) Combined With Chemoradiotherapy for Locally Advanced Cervical Cancer: A 2-Center Retrospective Study., PMID:39043041
Tofacitinib Regulates Endostatin via Effects on CD147 and Cathepsin S., PMID:39000375
Serum Vascular Endothelial Growth Factor and Endostatin as an Adjunct to Clinical Decision Making in Managing Radiation-induced Changes Post Gamma Knife Radiosurgery in Spetzler Martin Grade 3 Arteriovenous Malformations Patients: A Pilot Study., PMID:38981563
A single-center, retrospective study-spring-evaluating the efficacy and safety of recombinant human vascular endothelial inhibitor combined with anti-PD-1 in elderly patients aged 80 and above with NSCLC., PMID:38979430
Revisiting the focal role of endostatin and environmental factors in Alzheimer's disease., PMID:38951391
Efficacy and safety of PD-1 inhibitors plus chemotherapy with or without endostatin for stage IV lung squamous cancer: a retrospective study., PMID:38911862
Immunotherapy combined with antiangiogenic therapy as third- or further-line therapy for stage IV non-small cell lung cancer patients with ECOG performance status 2: A retrospective study., PMID:38872402
Collagen 18A1/Endostatin Expression in the Progression of Right Ventricular Remodeling and Dysfunction in Pulmonary Arterial Hypertension., PMID:38861354
Matrisome Transcriptome Dynamics during Tissue Aging., PMID:38792614
A meta-analysis of recombinant human endostatin combined with NP regimen for treating non-small cell lung cancer., PMID:38788043
Acute cardiac tamponade after Endostar treatment of non-small cell lung cancer: A case report., PMID:38728498
Effects of concurrent chemoradiotherapy with or without Endostar on the regression of retropharyngeal lymph node and prognosis of patients with locally advanced nasopharyngeal carcinoma: a retrospective study., PMID:38703186
The efficacy and safety of continuous intravenous infusion of rh-endostatin combined with platinum-based doublet chemotherapy for advanced non-small-cell lung cancer., PMID:38700579
AZGP1 deficiency promotes angiogenesis in prostate cancer., PMID:38659028
A multi-ancestry GWAS of Fuchs corneal dystrophy highlights the contributions of laminins, collagen, and endothelial cell regulation., PMID:38582945
Two patients with Knobloch syndrome due to mutation in COL8A1 gene: case report and review of the literature., PMID:38575892
[Features of genetic mutations in children with high myopia combined with peripheral retinal degenerations]., PMID:38450462
Endostar acts as a pneumonitis protectant in patients with locally advanced non-small cell lung cancer receiving concurrent chemoradiotherapy., PMID:38395838
Microvascular damage, neuroinflammation and extracellular matrix remodeling in Col18a1 knockout mice as a model for early cerebral small vessel disease., PMID:38387749
Nontargeted Plasma Proteomic Analysis of Renal Disease and Pulmonary Hypertension in Patients with Sickle Cell Disease., PMID:38353026
Multi-omics sequencing revealed endostar combined with cisplatin treated non small cell lung cancer via anti-angiogenesis., PMID:38331776
Predictive potential of various plasma inflammation-, angiogenesis-, and extracellular matrix remodeling-associated mediators for intra-amniotic inflammation and/or microbial invasion of the amniotic cavity in preterm labor., PMID:38329550
Soluble CD147 regulates endostatin via its effects on the activities of MMP-9 and secreted proteasome 20S., PMID:38318187
Antibody-Drug Conjugate αEGFR-E-P125A Reduces Triple-negative Breast Cancer Vasculogenic Mimicry, Motility, and Metastasis through Inhibition of EGFR, Integrin, and FAK/STAT3 Signaling., PMID:38315147
For research use only. Not for human or drug use.
