Catalog No.
YHE14101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Cys24-Pro211
Predicted molecular weight
24.00 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P35625
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Protein MIG-5, TIMP-3, Tissue inhibitor of metalloproteinases 3, TIMP3, Metalloproteinase inhibitor 3
Synergistic Reversal of Inflammation-Mediated Degeneration in Intervertebral Discs: Phenylboric Acid-Grafted Hyaluronic Acid Hydrogel as an Anti-Oxidative Vehicle for Timp-3 Delivery and Promotion of Extracellular Matrix Synthesis., PMID:40484295
Investigation of potential protein biomarkers for the screening of placental-mediated fetal growth restriction disorders using targeted proteomics Olink technology., PMID:40453069
3,4-Dihydroxybenzoic acid methyl ester from Vespa velutina auraria Smith against rheumatoid arthritis via modulating the apoptosis and inflammation through NF-κB pathway., PMID:40448819
Effects of Different Doses of Glucosamine Hydrochloride on Cartilage Tissue and Levels of Joint Injury Markers in Knee Osteoarthritis., PMID:40387631
From cancer to heart fibrosis - GLIPR1 highlights a subset of myofibroblasts responsive to mesenchymal stem cell therapy after myocardial infarction., PMID:40306172
Investigation of the Pathogenesis of Liver Fibrosis Associated with Type 2 Diabetes Mellitus via Bioinformatic Analysis., PMID:40299397
Systematic Review of Relevant Biomarkers for Human Connective Tissue Repair and Healing Outcome: Implications for Understanding Healing Processes and Design of Healing Interventions., PMID:40248898
Characterization of Protein Expression and Signaling Pathway Activation That May Contribute to Differential Biological Functions in Porcine Arterial and Venous Smooth Muscle Cells., PMID:40243809
Transcriptomic analysis reveals distinct molecular signatures and regulatory networks of osteoarthritic chondrocytes versus mesenchymal stem cells during chondrogenesis., PMID:40242907
Extracellular Vesicles from Adipose-Derived Mesenchymal Stem Cells Improve Ligament-Bone Integration After Anterior Cruciate Ligament Primary Repair in Rabbit., PMID:40149932
Interaction of tissue inhibitor of metalloproteinase 3 gene polymorphism, blood cadmium and total urinary arsenic levels on clear cell renal cell carcinoma., PMID:40133536
Circular RNA circDCUN1D4 suppresses hepatocellular carcinoma development via targeting the miR-590-5p/ TIMP3 axis., PMID:40128740
TIMP3 deficiency accelerates UVB-induced HaCaT cell senescence by regulating ferroptosis., PMID:40117061
Genetic Associations with the Susceptibility to High-Altitude Pulmonary Edema in the Japanese Population., PMID:40094446
Deciphering the value of anoikis-related genes in prognosis, immune microenvironment, and drug sensitivity of laryngeal squamous cell carcinoma., PMID:40020330
Effect of TIMPs and their minimally engineered variants in blocking invasion and migration of brain cancer cells., PMID:40019229
Occurrence of cellular senescence in chronic human shoulder tendinopathies and its attenuation ex vivo by inhibition of Enhancer of Zeste 2., PMID:39996291
An In Vitro Investigation of Levofloxacin-Induced Cytotoxicity in Rat Bone Marrow Mesenchymal Stem Cells., PMID:39991432
Novel plasma biomarkers of amyloid plaque pathology and cortical thickness: Evaluation of the NULISA targeted proteomic platform in an ethnically diverse cohort., PMID:39989429
Parallel Networks to Predict TIMP and Protease Cell Activity of Nucleus Pulposus Cells Exposed and Not Exposed to Pro-Inflammatory Cytokines., PMID:39981424
GC-MSCs transcriptionally upregulate SALL4 in gastric cancer through miR-4669/TIMP3/β-catenin signaling., PMID:39965736
IGFBP5 as a Novel Basolateral Secretion Marker in the Retinal Pigment Epithelium., PMID:39930222
Computational network analysis of two popular skin cancers provides insights into the molecular mechanisms and reveals common therapeutic targets., PMID:39866430
Aberrant DNA methylation of EDNRB, MGMT and TIMP3 gene promoters in saliva of head and neck carcinoma patients as a diagnostic tool., PMID:39847241
Expression of MMP1, MMP3, and TIMP1 in intervertebral discs under simulated overload and microgravity conditions., PMID:39833904
Transcriptomic and functional characterization of megakaryocytic-derived platelet-like particles: impaired aggregation and prominent anti-tumor effects., PMID:39812346
[Zhuanggu Jianxi Decoction reduces synovial tissue inflammation in human knee osteoarthritis by regulating LXRs/NF-κB signaling pathway]., PMID:39805794
MMP-3 and TIMP-1 as prognostic biomarkers in VZV-induced retinal necrosis., PMID:39723192
Metalloproteinase inhibitors regulate biliary progenitor cells through sDLK1 in organoid models of liver injury., PMID:39699962
Plasma levels of matrix metalloproteinases in early psychosis, anxiety and depression: Evidence from the ALSPAC cohort., PMID:39615606
Endostatin-expressing endometrial mesenchymal stem cells inhibit angiogenesis in endometriosis through the miRNA-21-5p/TIMP3/PI3K/Akt/mTOR pathway., PMID:39589222
Effects of Conditioned Media From Human Umbilical Cord-Derived Mesenchymal Stem Cells on Tenocytes From Degenerative Rotator Cuff Tears in an Interleukin 1β-Induced Tendinopathic Condition., PMID:39534392
Small heterodimer partner-interacting leucine zipper protein suppresses pain and cartilage destruction in an osteoarthritis model by modulating the AMPK/STAT3 signaling pathway., PMID:39533324
[Fibulin-3 Regulates Tissue Inhibitor of Metalloproteinases 3 to Inhibit Senescence in Intervertebral Disc Nucleus Pulposus Cells]., PMID:39507955
Long-Term Effect of TIMP3 Gene Expression on Thyroid Cancer: A Cure Model Analysis., PMID:39471030
Genetic removal of Nlrp3 protects against sporadic and R345W Efemp1-induced basal laminar deposit formation., PMID:39464028
Alterations in the placental proteome in association with the presence of black carbon particles: A discovery study., PMID:39442658
Multi-analyte proteomic analysis identifies blood-based neuroinflammation, cerebrovascular and synaptic biomarkers in preclinical Alzheimer's disease., PMID:39385222
Human iPSC-based disease modeling studies identify a common mechanistic defect and potential therapies for AMD and related macular dystrophies., PMID:39362220
LRP1 Repression by SNAIL Results in ECM Remodeling in Genetic Risk for Vascular Diseases., PMID:39355906
SORBS2-Mediated inhibition of malignant behaviors in esophageal squamous cell carcinoma through TIMP3., PMID:39288625
SIRT1 mediates the inflammatory response of macrophages and regulates the TIMP3/ADAM17 pathway in atherosclerosis., PMID:39271099
Exploring the Novel Potential of Serum SIRT1 and TIMP3 as Biomarkers for In-Stent Restenosis Following Percutaneous Transluminal Angioplasty and Stenting in Arteriosclerosis Obliterans Patients., PMID:39231729
Exosomal miR-21-5p derived from endometrial stromal cells promotes angiogenesis by targeting TIMP3 in ovarian endometrial cysts., PMID:39227403
Novel therapeutic targets for primary open-angle glaucoma identified through multicenter proteome-wide mendelian randomization., PMID:39221148
Tissue inhibitor of metalloproteinase-3 expression affects clinicopathological features and prognosis of aflatoxin B1-related hepatocellular carcinoma., PMID:39221097
Chondroid Synoviocytic Neoplasm: A Clinicopathologic, Immunohistochemical, and Molecular Genetic Study of a Distinctive Tumor of Synoviocytes., PMID:39181450
Expression of matrix metalloproteinases and their inhibitors in corneal stromal fibroblasts and keratocytes from healthy and keratoconus corneas., PMID:39177803
Elucidation of the anti-colorectal cancer mechanism of Atractylodes lancea by network pharmacology and experimental verification., PMID:39177661
Neuroprotective effects of resveratrol through modulation of PI3K/Akt/GSK-3β pathway and metalloproteases., PMID:39159067
For research use only. Not for human or drug use.
