Catalog No.
YHE10101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Phe187-Asn425
Predicted molecular weight
30.52 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P35354
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PGH synthase 2, Prostaglandin G/H synthase 2, Cyclooxygenase-2, PTGS2, COX2, PGHS-2, PHS II, Prostaglandin-endoperoxide synthase 2, COX-2, Prostaglandin H2 synthase 2
Aqueous Extract of Freshwater Clam Increases Alcohol Metabolism in Rats in a Preclinical Model., PMID:40507184
CYR61 and CTGF mediate the stimulatory effect of amphiregulin on COX-2 expression in human granulosa-lutein cells., PMID:40506006
Uncovering the pharmacological mechanisms of bifendate against chronic kidney disease using computational pharmacology and experimental verification., PMID:40505415
Anti-inflammatory effect of photobiomodulation in the brain following local peripheral carrageenan-induced inflammation., PMID:40500489
Dynamic VOC fingerprinting and mechanistic exploration of medicinal edible fungus Inonotus hispidus: A combination of HS-GC-IMS/MS multivariate analysis and network-based pharmacology., PMID:40499502
Syringetin ameliorates thallium sulphate induced renal dysfunction via regulating Nrf2/Keap-1, TLR4/HMGB1/RAGE and NF-κB pathway., PMID:40494130
Linarin Relieves Apoptosis, Inflammation and Oxidative Stress in LPS-Induced Acute Kidney Injury by Modulating COX2., PMID:40491178
The preventive effect of solubilized sturgeon oil on dextran sulfate sodium-induced ulcerative colitis via inflammation attenuation and intestinal microbiota regulation., PMID:40488649
Mechanisms Underlying the Therapeutic Effects of Brucea javanica in Cervical Cancer Treatment Based on Network Pharmacology and Molecular Docking., PMID:40487864
Cyclooxygenase-2 Overexpression and its Association with Histopathological Features of Human Malignant Melanoma., PMID:40487258
In-silico identification and experimental validation of shared genes and pathways to decipher the molecular links between COPD and MASLD., PMID:40482557
Celastrol protects against cisplatin-induced ovarian toxicity via modulation of PPAR-γ and AMPK., PMID:40481255
Protective effect of Allium hookeri water extract and its main compound, Cycloalliin, on foam cell formation in THP-1-derived macrophages., PMID:40475061
Metabolomics combined with network pharmacology reveals the anti-hepatoma effects of terpenoids from Polygonatum kingianum var. grandifolium and Polygonatum sibiricum Redouté as well as differences in their terpenoid metabolites., PMID:40474061
Development of a two-layer 3D equine endometrial tissue model using genipin-crosslinked collagen scaffolds and 3D printing., PMID:40473768
A double-edged effect of hypoxia on astrocyte-derived exosome releases., PMID:40469772
Rhein Alleviates Cisplatin-Induced Acute Kidney Injury via Downregulation of NOX4-COX2/PGFS Signaling Pathway., PMID:40469629
Huangqi fuling decoction inhibits the invasion and metastasis of gastric cancer via the TNF signaling pathway., PMID:40467576
TBX21 knockdown attenuates neuroinflammation induced by intracerebral hemorrhage via the SIRT1-WDR5-H3K4me3 axis., PMID:40466814
Exploring 5,7-dimethoxyflavone from Piper ornatum as a novel anti-breast cancer candidate: insights from in silico analysis., PMID:40465971
Integrative Network Pharmacology, Molecular Docking, and Dynamics Simulation Guided Discovery of Anethole, Carvacrol, Carnosol, Nicotine, and Paeonol as Potential Therapeutics for Parkinson's Disease., PMID:40465192
Mechanisms of Zanthoxyli Pericarpium-Zingiberis Rhizoma in the Treatment of Gastric Cancer Based on Network Pharmacology and Experimental Validation., PMID:40464032
Probiotics ameliorate H. pylori-associated gastric β-catenin and COX-2 carcinogenesis signaling by regulating miR-185., PMID:40462044
[Integrated multiomics reveal mechanism of Aidi Injection in attenuating doxorubicin-induced cardiotoxicity]., PMID:40461234
Metabolism and Mendelian randomization study on the mechanism of Buyang Huanwu Decoction in regulating iron metabolism and improving cerebral ischemia-reperfusion injury., PMID:40460920
TLR4 and prostaglandin pathways at the crossroads of endotoxemia-induced lipolysis., PMID:40458405
EBV Reactivation-associated gene signature predicts poor prognosis in nasopharyngeal carcinoma., PMID:40457434
Chrysin Mitigates Chromium-Induced Nephrotoxicity Via Modulation of AMPK/SIRT1/NF-κB/p53 Signaling Cascade and PGC-1α Signaling., PMID:40457156
In vivo DMBA induced mouse skin epithelial hypertrophy and associated molecular changes during various intervals within 24-hour of exposure and their prevention by natural agents., PMID:40454912
Korean black ginseng extract alleviates Alzheimer's disease-related cognitive impairment by activating the Nrf2/HO-1 pathway and suppressing the p38 MAPK/NF-κB/STAT3 pathways and NLRP3 inflammasome via TLR2 and TLR4 modulation., PMID:40453349
Alleviation of dextran sulfate sodium (DSS)-induced colitis in mice through the antioxidative effects of muscone via the MyD88/p38 MAPK signalling pathway., PMID:40452925
The mechanisms of Brucea javanica in the treatment of oral squamous cell carcinoma: a network pharmacology, molecular docking, and experimental study., PMID:40452077
Anti-inflammatory Function of Ozonated Ethyl Ester of Unsaturated Fatty Acids., PMID:40451818
MitoQ for vitiligo by mitigating PARP1 translocation aberrations: Network pharmacology and experimental validation., PMID:40451398
New insights into the pharmacological mechanisms of Jinqi Jiangtang Tablets in the treatment of type 2 diabetes mellitus: A multi-omics approach combined with experimental validation., PMID:40449695
6-shogaol, a bioactive component of ginger, alleviates aging-induced ocular inflammation and ER stress in the 25-month-old mice., PMID:40449688
Changes in Gene Transcription in Cumulus Cells from Women of Advanced Maternal Age under the Influence of Extracellular Vesicles from Follicular Fluid of Young Donors., PMID:40448879
Effects of extreme heat exposure on heatstroke and liver injury in mice: The role of PPARα., PMID:40445822
March6 Protects Against Acute Kidney Injury by Suppressing Renal Tubular Epithelial Cell Ferroptosis Through the Destabilization of P53 and ACSL4 Proteins., PMID:40445517
Metabolomics and network pharmacology based study of the potential of Brassica rapa L. extract BREE-Ea for the treatment of Alzheimer's disease., PMID:40445088
Involvement of EGFR-AKT signaling in hemin-induced neurotoxicity., PMID:40444141
Wogonin inhibits the proliferation of prolactinoma through the PI3K/AKT signaling pathway., PMID:40444042
Study of the ameliorative effect of β-Bisabolene on ischemic stroke via COX-2 with the Keap1/Nrf2 and MAPK pathways., PMID:40441590
Environmental protein corona on nanoplastics altered the responses of skin keratinocytes and fibroblast cells to the particles., PMID:40440896
Activation of eIF2α-ATF4 by endoplasmic reticulum-mitochondria coupling stress enhances COX2 expression and MSC-based therapeutic efficacy for rheumatoid arthritis., PMID:40437626
A novel role of celecoxib in the inhibition of calcium-activated chloride channel ANO1., PMID:40436482
Therapeutic role of Crateva religiosa in diabetic nephropathy: Insights into key signaling pathways., PMID:40435181
Dihydroartemisinin Alleviates Ulcerative Colitis via Target Identification and Pathway Modulation: A Cyberpharmacology Approach., PMID:40433891
Dexrazoxane Attenuates Blood-Brain Barrier Injury During Venoarterial Extracorporeal Membrane Oxygenation., PMID:40433882
Antipyretic Mechanism of Bai Hu Tang on LPS-Induced Fever in Rat: A Network Pharmacology and Metabolomics Analysis., PMID:40430430
For research use only. Not for human or drug use.
