Catalog No.
YHE05001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Thr261-Cys399
Predicted molecular weight
18.04 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P34820
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
BMP8B, Bone morphogenetic protein 8B, OP-2, BMP8, BMP-8, Osteogenic protein 2, BMP-8B
Bone morphogenetic protein 8B (BMP8B) increases the glucose sensitivity of ventromedial hypothalamus (VMH) glucose-inhibited (GI) neurons in female mice., PMID:40181907
Putative Dual Roles of Bone Morphogenetic Protein 8B (BMP8B) in Disease Progression of Gastric Cancer., PMID:39238632
Osteokines in Nonalcoholic Fatty Liver Disease., PMID:39225951
The prognostic significance and immune characteristics of bone morphogenetic proteins (BMPs) family: A pan-cancer multi-omics analysis., PMID:39031404
Neuregulin4-ErbB4 signalling pathway is driven by electroacupuncture stimulation to remodel brown adipose tissue innervation., PMID:38951947
p200CUX1-regulated BMP8B inhibits the progression of acute myeloid leukemia via the MAPK signaling pathway., PMID:38819709
Cold exposure modulates potential brown adipokines in humans, but only FGF21 is associated with brown adipose tissue volume., PMID:38247441
BMP8B Activates Both SMAD2/3 and NF-κB Signals to Inhibit the Differentiation of 3T3-L1 Preadipocytes into Mature Adipocytes., PMID:38201894
Circulatory bone morphogenetic protein (BMP) 8B is a non-invasive predictive biomarker for the diagnosis of non-alcoholic steatohepatitis (NASH)., PMID:38127951
IL-6 Reduces Spheroid Sizes of Osteophytic Cells Derived from Osteoarthritis Knee Joint via Induction of Apoptosis., PMID:37918800
Coding and noncoding RNA profile of human heterotopic ossifications - Risk factors and biomarkers., PMID:37597797
Integrative multi-omics analyses unravel the immunological implication and prognostic significance of CXCL12 in breast cancer., PMID:37564657
Aberrant expression of bone morphogenetic proteins in the disease progression and metastasis of breast cancer., PMID:37333824
FAM20A mutations and transcriptome analyses of dental pulp tissues of enamel renal syndrome., PMID:37159186
Adipocyte YTH N(6)-methyladenosine RNA-binding protein 1 protects against obesity by promoting white adipose tissue beiging in male mice., PMID:36914671
Disease progression promotes changes in adipose tissue signatures in type 2 diabetic (db/db) mice: The potential pathophysiological role of batokines., PMID:36521548
Unveiling the transcriptomic landscape and the potential antagonist feedback mechanisms of TGF-β superfamily signaling module in bone and osteoporosis., PMID:36443839
The relationship of antipsychotic treatment with reduced brown adipose tissue activity in patients with schizophrenia., PMID:35594830
Bone Morphogenetic Protein-8B Levels at Birth and in the First Year of Life: Relation to Metabolic-Endocrine Variables and Brown Adipose Tissue Activity., PMID:35402348
Obesity induces resistance to central action of BMP8B through a mechanism involving the BBSome., PMID:35218946
Genetics of ovarian insufficiency and defects of folliculogenesis., PMID:34794894
Expression of Cytokine-Coding Genes BMP8B, LEFTY1 and INSL5 Could Distinguish between Ulcerative Colitis and Crohn's Disease., PMID:34680872
BMP8 and activated brown adipose tissue in human newborns., PMID:34489410
A Differential Pattern of Batokine Expression in Perivascular Adipose Tissue Depots From Mice., PMID:34421656
Production of viable chicken by allogeneic transplantation of primordial germ cells induced from somatic cells., PMID:34017000
Stem cell characteristics promote aggressiveness of diffuse large B-cell lymphoma., PMID:33288848
Pathophysiological mechanisms underlying MAFLD., PMID:32998095
Bone morphogenetic protein 8B promotes the progression of non-alcoholic steatohepatitis., PMID:32694734
Transcriptome profiling reveals signaling conditions dictating human spermatogonia fate in vitro., PMID:32661178
Phthalate exposure causes browning-like effects on adipocytes in vitro and in vivo., PMID:32522588
Contralesional Application of Transcranial Direct Current Stimulation on Functional Improvement in Ischemic Stroke Mice., PMID:32521221
Effects of Royal Jelly and Tocotrienol Rich Fraction in obesity treatment of calorie-restricted obese rats: a focus on white fat browning properties and thermogenic capacity., PMID:32508963
Adipose tissue depot differences in adipokines and effects on skeletal and cardiac muscle., PMID:32387807
A gene co-expression network analysis of the candidate genes and molecular pathways associated with feather follicle traits of chicken skin., PMID:32378263
Inner Mongolian Cashmere Goat Secondary Follicle Development Regulation Research Based on mRNA-miRNA Co-analysis., PMID:32161290
Exploring the role of Luman/CREB3 in regulating decidualization of mice endometrial stromal cells by comparative transcriptomics., PMID:32000663
Human BMP8A suppresses luteinization of rat granulosa cells via the SMAD1/5/8 pathway., PMID:31940275
High expression of bone morphogenetic protein (BMP) 6 and BMP7 are associated with higher immune cell infiltration and better survival in estrogen receptor‑positive breast cancer., PMID:31524275
Bone Morphogenetic Protein-8B Expression is Induced in Steatotic Hepatocytes and Promotes Hepatic Steatosis and Inflammation In Vitro., PMID:31096638
Small molecules for fat combustion: targeting obesity., PMID:30976490
Therapeutic effect of adipose-derived mesenchymal stem cells on Cisplatin induced testicular damage in adult male albino rat., PMID:30741078
Beyond the bone: Bone morphogenetic protein signaling in adipose tissue., PMID:30609449
Troglitazone activates TRPV1 and causes deacetylation of PPARγ in 3T3-L1 cells., PMID:30496795
Adipocyte-secreted BMP8b mediates adrenergic-induced remodeling of the neuro-vascular network in adipose tissue., PMID:30478315
Adipocytes spectrum - From homeostasia to obesity and its associated pathology., PMID:30049662
Whole exome sequencing of benign pulmonary metastasizing leiomyoma reveals mutation in the BMP8B gene., PMID:29386003
Involvement of the bone morphogenic protein/SMAD signaling pathway in the etiology of congenital anomalies of the kidney and urinary tract accompanied by cryptorchidism., PMID:29197384
Do estrogens enhance activation of brown and beiging of adipose tissues?, PMID:28988965
BMP8A sustains spermatogenesis by activating both SMAD1/5/8 and SMAD2/3 in spermatogonia., PMID:28465413
TRPV1 activation counters diet-induced obesity through sirtuin-1 activation and PRDM-16 deacetylation in brown adipose tissue., PMID:28104916
For research use only. Not for human or drug use.
