Catalog No.
YHE01401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu858-Ile999
Predicted molecular weight
41.51 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P32926
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Cadherin family member 6, DSG3, Desmoglein-3, 130 kDa pemphigus vulgaris antigen, PVA, CDHF6
Desmoglein-3 autoantibodies in tissues of oral lichen planus patients and its correlation with disease severity: case-control study., PMID:40481453
Factors associated with persistent anti-desmoglein positivity after remission in pemphigus vulgaris: a prospective registry-based cohort study., PMID:40433384
Epac1 contributes to apremilast-mediated rescue of pemphigus autoantibody-induced loss of keratinocyte adhesion., PMID:40299565
Elevated Fab glycosylation of autoantibodies maintained during B cell depletion therapy., PMID:40295683
[CAR-T cells in Dermatology: Mechanisms of action and applications in autoimmune diseases]., PMID:40279442
Epitomic profiling and functional characteristics of pemphigus vulgaris autoantibody binding to keratinocyte M3 muscarinic acetylcholine receptor., PMID:40120680
Clinical Features, Diagnosis and Treatment of Different Types of Paediatric Pemphigus., PMID:40059466
Molecular Markers of Occult Lymph Node Metastasis in Head and Neck Squamous Cell Carcinoma (HNSCC) Patients., PMID:40018925
Prevalence and pathogenic activity of anti-desmocollin-3 antibodies in patients with pemphigus vulgaris and pemphigus foliaceus., PMID:39989391
Optimizing Pemphigus Management With Rituximab and Short-Term Relapse Predictors., PMID:39908046
The impact of signaling pathways on the desmosome ultrastructure in pemphigus., PMID:39882246
Case report: A rollercoaster journey of pemphigus vegetans., PMID:39872528
Pemphigus relapse: Mechanisms, risk factors, and agents associated with disease recurrence., PMID:39460496
Quality-controlled characterization of a monoclonal antibody specific to an EC5-domain of human desmoglein 3 for pemphigus research., PMID:39450179
IgG reactivity to different desmoglein-3 ectodomains in pemphigus vulgaris: novel panels for assessing disease severity., PMID:39416775
Human dental mesenchymal stem cells restorate immune response in sera of pemphigus vulgaris patients., PMID:39352524
Effect of opioid receptor antagonist on mitigating tumor necrosis factor-like weak inducer of apoptosis (TWEAK)-induced apoptolysis in pemphigus pathogenesis., PMID:39276627
Unbiased screening identifies regulators of cell-cell adhesion and treatment options in pemphigus., PMID:39271654
Comparison of serum cytokines and chemokines levels and clinical significance in patients with pemphigus vulgaris-A retrospective study., PMID:39246287
Standardized Production of Anti-Desmoglein 3 Antibody AK23 for Translational Pemphigus Vulgaris Research., PMID:39169810
Pathogenic relevance of antibodies against desmoglein 3 in patients with oral lichen planus., PMID:39152677
Direct immunofluorescence on plucked hair outer root sheath can predict relapse in pemphigus vulgaris., PMID:39086016
Alteration of reactive oxygen species master transcription factor Nrf2 in keratinocytes exposed to monoclonal pathogenic antibody AK23 against desmoglein-3 in pemphigus vulgaris., PMID:39037929
Mutant TP53 promotes invasion of lung cancer cells by regulating desmoglein 3., PMID:38900156
Factors associated with non-pathogenic antibodies against desmoglein-3 in pemphigus foliaceus., PMID:38851894
The emergence of circulating activated autoreactive desmoglein 3-specific follicular regulatory T cells is associated with long-term efficacy of rituximab in patients with pemphigus vulgaris., PMID:38848544
Absence of Epidermal Antibodies in Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Patients but Beware of Single Positive Results., PMID:38803350
A case of bullous pemphigoid complicated by mucosal lesions due to mucosal-dominant pemphigus vulgaris: analyzing the pathogenicity of anti-desmoglein 3 antibodies using a bead aggregation assay., PMID:38741281
Desmosomal Hyper-Adhesion Affects Direct Inhibition of Desmoglein Interactions in Pemphigus., PMID:38677661
EGFR Inhibition by Erlotinib Rescues Desmosome Ultrastructure and Keratin Anchorage and Protects against Pemphigus Vulgaris IgG-Induced Acantholysis in Human Epidermis., PMID:38642796
Clinical and immunological predictors of post-rituximab paradoxical pemphigus flare: A prospective cohort study., PMID:38595008
Differences among Indian and European pemphigus patients based on demographics, clinical parameters and propensity for relapse: results of a prospective bicontinental cohort study., PMID:38465545
Rituximab in the Management of Autoimmune Bullous Diseases: A Treatment-Resistant Case Series from a Single Central European Referral Center., PMID:38399557
ERK/MEK Pathway Regulates Th17 Cell Differentiation in Patients with Pemphigus Vulgaris., PMID:38371571
Aspirin-exacerbated respiratory disease is associated with variants in filaggrin, epithelial integrity, and cellular interactions., PMID:38317805
Sustained Remission Without Corticosteroids Among Patients With Pemphigus Who Had Rituximab as First-Line Therapy: Follow-Up of the Ritux 3 Trial., PMID:38265821
JNK inhibition enhances cell-cell adhesion impaired by desmoglein 3 gene disruption in keratinocytes., PMID:38227055
Novel nanoparticle AuNCs conjugated with Desmoglein-3 antibody for FL/CT dual-mode targeted imaging and precise treatment of lung squamous cell carcinoma., PMID:38224630
A case of anti-laminin γ1 (p200) pemphigoid developed after dipeptidyl peptidase-4 inhibitor administration., PMID:38214494
Pemphigus vulgaris relapsed with serological shift from single-positive desmoglein-3 antibodies to single-positive desmoglein-1 antibodies., PMID:38212901
A case of paraneoplastic pemphigus associated with follicular lymphoma positive only for anti-desmoglein 3 antibody., PMID:38111329
Bioinformatics analysis of human kallikrein 5 (KLK5) expression in metaplastic triple-negative breast cancer., PMID:38090381
Comparative Transcriptome Analysis Identifies Desmoglein-3 as a Potential Oncogene in Oral Cancer Cells., PMID:38067138
Ferroptosis-related genes prognostic signature for pancreatic cancer and immune infiltration: potential biomarkers for predicting overall survival., PMID:38007403
Treatment with a red-laser-based wound therapy device exerts positive effects in models of delayed keratinocyte and fibroblast wound healing., PMID:37957888
Tacrolimus reverses pemphigus vulgaris serum-induced depletion of desmoglein in HaCaT cells via inhibition of heat shock protein 27 phosphorylation., PMID:37940861
Homozygous deletion of the DSG3 terminal exon associated with acantholytic blistering of the oral and laryngeal mucosa., PMID:37850634
Thalidomide Alleviates Apoptosis, Oxidative Damage and Inflammation Induced by Pemphigus Vulgaris IgG in HaCat Cells and Neonatal Mice Through MyD88., PMID:37719363
Type 2 T-Cell Responses against Distinct Epitopes of the Desmoglein 3 Ectodomain in Pemphigus Vulgaris., PMID:37717934
Serologic Biomarkers in Pemphigus Monitoring: C-reactive Protein, Macrophage Migration Inhibitory Factor, and Prolactin Levels Versus Autoantibody Assays., PMID:37524667
For research use only. Not for human or drug use.
