Catalog No.
YHD99701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser32-Leu240
Predicted molecular weight
26.92 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P32297
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NACHRA3, Neuronal acetylcholine receptor subunit alpha-3, CHRNA3
Transforming Properties of E6/E7 Oncogenes from Beta-2 HPV80 in Primary Human Fibroblasts., PMID:40508156
Ursolic acid derivative UA312 ameliorates ionizing radiation-induced cardiotoxicity and neurodevelopmental toxicity in zebrafish via targeting chrna3 and grik5., PMID:40295836
Association of SNPs in nAChRs genes, areca nut chewing and smoking, and their interaction with lung cancer in Hainan, China: a case control study., PMID:40197297
Nicotinic acetylcholine receptors regulate growth hormone in pituitary somatotrophs of tigers., PMID:40164859
Investigating the role of eight SNPs in CHRNA3 for COPD susceptibility in the Chinese elderly population., PMID:40072291
The Cholinergic Receptor Nicotinic α3 Was Reduced in the Hippocampus of Early Cognitively Impaired Adult Male Mice and Upregulated by Nicotine and Cytisine in HT22 Cells., PMID:40072069
Nicotinic Acetylcholine Receptor Expression in Merkel Cell Carcinoma Is Associated With Clinical and Histopathologic Parameters., PMID:39814046
Novel Transgenic Zebrafish Lines to Study the CHRNA3-B4-A5 Gene Cluster., PMID:39686588
CHRNA5-A3-B4, CYP2A6, and DBH Genetic Associations With Smoking Cessation Throughout Adulthood Within Two Longitudinal Studies of Women., PMID:39673390
Cannabinol (CBN) Influences the Ion Channels and Synaptic-Related Genes in NSC-34 Cell Line: A Transcriptomic Study., PMID:39329756
Abundant extrasynaptic expression of α3β4-containing nicotinic acetylcholine receptors in the medial habenula-interpeduncular nucleus pathway in mice., PMID:38902419
Investigating CHRNA5, CHRNA3, and CHRNB4 variants in the genetic landscape of substance use disorder in Jordan., PMID:38862938
Risk Factors of Depression Screened by Two-Sample Mendelian Randomization Analysis: A Systematic Review., PMID:38326723
Novel CHRNA3 variants identified in a patient with bladder dysfunction, dysautonomia, and gastrointestinal dysmotility., PMID:38192228
Sensory innervation of masseter, temporal and lateral pterygoid muscles in common marmosets., PMID:38155190
Are novel treatments for brain disorders hiding in plain sight?, PMID:37422511
Hyperconnectivity of Two Separate Long-Range Cholinergic Systems Contributes to the Reorganization of the Brain Functional Connectivity during Nicotine Withdrawal in Male Mice., PMID:37295945
Recessive CHRM5 variant as a potential cause of neurogenic bladder., PMID:37213061
Disconnected Cardiac Autonomic Nerves in Genetic Ganglionic Acetylcholine Receptor Alpha-3 Subunit Deficiency., PMID:37161764
Reprogramming the Circadian Dynamics of Epileptic Genes in Mouse Temporal Lobe Epilepsy., PMID:37047373
Cell-Free RNA from Plasma in Patients with Neuroblastoma: Exploring the Technical and Clinical Potential., PMID:37046768
Research into the characteristic molecules significantly affecting liver cancer immunotherapy., PMID:36860864
CHRNA5-A3-B4 and DRD2 Genes and Smoking Cessation Throughout Adulthood: A Longitudinal Study of Women., PMID:36794842
Expression of Chrna9 is regulated by Tbx3 in undifferentiated pluripotent stem cells., PMID:36709241
Differential gene expression during recall of behaviorally conditioned immune enhancement in rats: a pilot study., PMID:39834660
Potential Targets and Action Mechanism of Gastrodin in the Treatment of Attention-Deficit/Hyperactivity Disorder: Bioinformatics and Network Pharmacology Analysis., PMID:36133787
Association of Polymorphism CHRNA5 and CHRNA3 Gene in People Addicted to Nicotine., PMID:36078193
Spinal cord injury is associated with changes in synaptic properties of the mouse major pelvic ganglion., PMID:36069457
A systematic review of genetic variation within nicotinic acetylcholine receptor genes and cigarette smoking cessation., PMID:35981468
Impact of single nucleotide polymorphisms and cigarette smoking on cancer risk and survival of patients with head and neck squamous cell carcinoma., PMID:35830713
Integrative RNA profiling of TBEV-infected neurons and astrocytes reveals potential pathogenic effectors., PMID:35685361
Divergent Roles of α5 and β4 Nicotinic Receptor Subunits in Food Reward and Nicotine-induced Weight Loss in Male Mice., PMID:35595472
Common and distinguishing genetic factors for substance use behavior and disorder: an integrated analysis of genomic and transcriptomic studies from both human and animal studies., PMID:35491750
Nicotinic acetylcholine receptors in a songbird brain., PMID:35344610
Several nAChRs gene variants are associated with phenotypes of heroin addiction in Chinese Han population., PMID:35176404
A polygenic approach to the association between smoking and schizophrenia., PMID:34779080
The Cumulative Effect of Gene-Gene Interactions Between GSTM1, CHRNA3, CHRNA5 and SOD3 Gene Polymorphisms Combined with Smoking on COPD Risk., PMID:34707353
Genome-Wide Association Study of Peripheral Artery Disease., PMID:34601942
Association Study of Polymorphisms in Neuronal Nicotinic Acetylcholine Receptor Subunit Genes With Schizophrenia in the Han Chinese Population., PMID:34555889
Five New Cases of Megacystis-Microcolon-Intestinal Hypoperistalsis Syndrome (MMIHS), with One Case Showing a Novel Mutation., PMID:34383618
Application of Bioinformatics Methods to Identify Key Genes and Functions in Chronic Pelvic Pain., PMID:34381521
Chr15q25 Genetic Variant rs16969968 Alters Cell Differentiation in Respiratory Epithelia., PMID:34206324
Genetic Variants in Smoking-Related Genes in Two Smoking Cessation Programs: A Cross-Sectional Study., PMID:34205269
Downregulation of DNMT3a expression by RNAi and its effect on NF-κBs expression of thymic epithelial cells., PMID:34192561
Familial Autonomic Ganglionopathy Caused by Rare CHRNA3 Genetic Variants., PMID:33947782
Genetics of substance use disorders: a review., PMID:33879270
Genetic Factors Associated with COPD Depend on the Ancestral Caucasian/Amerindian Component in the Mexican Population., PMID:33801584
Nicotinic acetylcholine gene cluster CHRNA5-A3-B4 variants influence smoking status in a Bangladeshi population., PMID:33675519
The relationship between CHRNA5/A3/B4 gene cluster polymorphisms and lung cancer risk: An updated meta-analysis and systematic review., PMID:33578531
Colocalization of association signals at nicotinic acetylcholine receptor genes between schizophrenia and smoking traits., PMID:33454625
For research use only. Not for human or drug use.
