Catalog No.
YHD96501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Ala480
Predicted molecular weight
58.00 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P31749
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
RAC-alpha serine/threonine-protein kinase, RAC, RAC-PK-alpha, PKB alpha, Proto-oncogene c-Akt, Protein kinase B alpha, Protein kinase B, AKT1, PKB
Radiosynthesis of [131I]I-Hesperidin: Optimization, physicochemical profiling, and computational insights for targeted radiopharmaceuticals., PMID:40516338
Anticancer activity prediction of Curcuma longa and Phyllanthus urinaria through computational analysis., PMID:40510894
Molecular targets and mechanisms of cortex mori for lung cancer treatment: a network pharmacology study, molecular docking and in vitro and in vivo experimental validation., PMID:40510163
Network Pharmacology and Molecular Docking-Based Approach to Explore Potential Bioactive Compounds from Kaempferia parviflora on Chemokine Signaling Pathways in the Treatment of Psoriasis Disease., PMID:40508056
MSTN Regulates Bovine Skeletal Muscle Satellite Cell Differentiation via PSMA6-Mediated AKT Signaling Pathway., PMID:40507774
Wuda Granule Alleviates DSS-Induced Colitis in Mice by Inhibiting Inflammation, Protecting Intestinal Barrier and Reducing Oxidative Stress Through Nrf2/Keap1/HO-1 Pathway., PMID:40503489
[AKT1 E17K mutation of mucinous adenocarcinoma of the upper lip: report of a case]., PMID:40494773
Intranasal delivery of platelet cell membrane-cloaked Astragaloside IV loaded biomimetic nanoparticles for enhanced therapeutics in acute lung injury mice., PMID:40494449
Cornus officinalis loganin attenuates acute lung injury in mice via regulating the PI3K/AKT/NLRP3 axis., PMID:40490233
Network pharmacology and molecular docking-based characterization of the mechanisms through which Astragali Radix-Atractylodes macrocephala Koidz herb pair can treat membranous nephropathy., PMID:40489804
Integrative analysis reveals human endogenous retroviruses-linked immune signatures in schizophrenia., PMID:40488982
Mechanisms Underlying the Therapeutic Effects of Brucea javanica in Cervical Cancer Treatment Based on Network Pharmacology and Molecular Docking., PMID:40487864
Genome rearrangements induced by the stimulation of end-joining of DNA double strand breaks through multiple phosphorylation of MRE11 by the kinase PKB/AKT1., PMID:40479710
Unveiling the mechanisms of Tianjihuang in hepatocellular carcinoma: a network pharmacology and molecular docking study., PMID:40478357
Goat milk oligosaccharides improve growth and gut microbiota composition in stunted mice., PMID:40467228
Antithrombotic Effect of Ginkgo Biloba Extract: A Study Based on Network Pharmacological Analysis and In vivo Experiments., PMID:40462336
[Network pharmacology and molecular docking explore mechanism of Croci Stigma in treating immune checkpoint inhibitor-associated myocarditis]., PMID:40461207
Paridis Rhizoma Saponins ameliorate CCl4-induced liver fibrosis via modulation of the Nrf2-HO-1/NQO-1 and TGF-β1/Smads signaling pathways., PMID:40458200
A Unique Morpho-Physiological, Metabolomics, and Transcriptional Shift Under Combined Drought and Salinity Stress in Stevia rebaudiana Bertoni., PMID:40457779
The role of long non-coding ribonucleic acid HOXA11-AS in endometriosis therapy., PMID:40457415
The mechanisms of Brucea javanica in the treatment of oral squamous cell carcinoma: a network pharmacology, molecular docking, and experimental study., PMID:40452077
Exploring the mechanism by which BXSD decoction treats cervical cancer through the combination of network pharmacology and molecular docking analysis: Molecular mechanism of AKT1 and CASP3 protein., PMID:40451357
Network pharmacology and experimental validation of inflammation inhibition by ChuanKeZhi Injection in treating asthma., PMID:40450983
Multi-omics analysis of outer membrane vesicles from P. goldsteinii in a psoriasis mouse model., PMID:40449877
The interaction of HT-2 toxin and Akt1 on gene expression regulation in Kashin-Beck disease pathogenesis., PMID:40449756
New insights into the pharmacological mechanisms of Jinqi Jiangtang Tablets in the treatment of type 2 diabetes mellitus: A multi-omics approach combined with experimental validation., PMID:40449695
Computer-aided unveiling molecular mechanisms of Xylocarpus granatum against colorectal cancer: therapeutic intervention targeting P13K-AKT signaling pathway., PMID:40446548
Study on the Chemical Composition, Biological Activity, and Mechanism of Intervention in Erectile Dysfunction of Healthy Snow Lotus Wine., PMID:40443781
Uncovering the molecular mechanisms of tonifying kidney and activating blood Decoction against myocardial fibrosis using network Pharmacology and experimental validation., PMID:40442166
Integrating network pharmacology, quantitative transcriptomic analysis, and experimental validation revealed the mechanism of cordycepin in the treatment of obesity., PMID:40438591
Mutational analysis and protein expression of PI3K/AKT pathway in four mucinous cystadenocarcinoma of the breast., PMID:40437613
Therapeutic role of Crateva religiosa in diabetic nephropathy: Insights into key signaling pathways., PMID:40435181
Exploring the Epidemiology and Molecular Mechanisms of Riboflavin Against Chronic Kidney Disease Based on Data Mining, Single-Cell RNA Sequencing and Molecular Docking., PMID:40435123
Investigating the Mechanisms of Lycii fructus in Treating Nonalcoholic Fatty Liver Disease and Diabetes Comorbidity Through Network Pharmacology and Molecular Dynamics., PMID:40433113
Dietary Insulinogenic Amino Acid Restriction Improves Glucose Metabolism in a Neonatal Piglet Model., PMID:40431415
Pericarpium Trichosanthis Injection Protects Isoproterenol-Induced Acute Myocardial Ischemia via Suppressing Inflammatory Damage and Apoptosis Pathways., PMID:40427511
Integrative in silico and in vivo Drosophila model studies reveal the anti-inflammatory, antioxidant, and anticancer properties of red radish microgreen extract., PMID:40425671
Shared molecular mechanisms of bisphenol A and phthalates in endometriosis: A bioinformatics and molecular docking study., PMID:40424730
Computational Modeling of Network Topology and Molecular Dynamics for the Assessment of Therapeutic Potential of the Astragalus Membranaceus-Salvia Miltiorrhiza Drug Pair in the Treatment of Chronic Kidney and Heart Failure., PMID:40424487
Yangke powder alleviates OVA-induced allergic asthma by inhibiting the PI3K/AKT/NF-κB signaling pathway., PMID:40420184
AI-Driven Multiscale Study on the Mechanism of Polygonati Rhizoma in Regulating Immune Function in STAD., PMID:40415801
Mechanism of Rhizoma Polygonati in the treatment of Alzheimer's disease based on network pharmacology and molecular docking., PMID:40412586
Helium governs nitric oxide signaling to improve alfalfa salinity tolerance by reestablishing redox and ion homeostasis., PMID:40412226
Eleutheroside A inhibits PI3K/AKT1/mTOR-mediated glycolysis in MDSCs to alleviate their immunosuppressive function in gastric cancer., PMID:40409102
Investigation of Fructus sophorae extract's therapeutic mechanism in atrophic vaginitis based on network pharmacology and experimental validation., PMID:40406491
Zhi-Zi-Chi decoction ameliorates depression-like behavior in chronic unpredictable mild stress-induced mice via the PI3K/AKT/mTOR signaling pathway., PMID:40403895
TP53 Mutations and Phosphatidylinositol 3-Kinase/AKT Pathway Alterations Are Key Determinants of Breast Cancer Outcome Independent of Subtype and Stage., PMID:40403210
Genetic predictors of longevity and survival in cellular homeostasis genes: A case-control study., PMID:40398646
Investigation of the material basis and mechanism of Qingfei Paidu granules in treating LPS-induced acute pneumonia using UPLC-Q-TOF-MS/MS, network pharmacology, molecular docking and experimental verification., PMID:40398242
Honokiol in the treatment of triple-negative breast cancer: a network pharmacology approach and experimental validation., PMID:40398092