Catalog No.
EHD95101
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Met1-Ser61
Predicted molecular weight
30.17 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P31358
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Human epididymis-specific protein 5, CDW52, CAMPATH-1 antigen, Cambridge pathology 1 antigen, He5, HE5, Epididymal secretory protein E5, CD52, CDw52
Expression of NUF2 and CD52 and Their Correlation With Chemotherapy Resistance and Prognosis in Patients With Non-Small Cell Lung Cancer., PMID:40421783
Epstein-Barr virus induces aberrant B cell migration and diapedesis via FAK-dependent chemotaxis pathways., PMID:40389409
Whole-Blood RNA Sequencing Profiling of Patients With Rheumatoid Arthritis Treated With Tofacitinib., PMID:40388487
Investigation of hub-shared genes and regulatory mechanisms of rheumatoid arthritis and atherosclerosis., PMID:40289029
Development and characterization of the novel MYD88 mutated, 6q deleted BCWM.2 cell line for Waldenström macroglobulinaemia., PMID:40254718
Alemtuzumab for haematological malignancies., PMID:40214729
Single-cell sequencing exposes mast cell-derived CD52's anti-tumor action in breast cancer through the IL-6/JAK/STAT3 axis., PMID:40194575
T-cell prolymphocytic leukemia, a case report and review of the literature., PMID:40109866
Single-cell analysis of CD14+CD16+ monocytes identifies a subpopulation with an enhanced migratory and inflammatory phenotype., PMID:40051633
The molecular basis of immunosuppression by soluble CD52 is defined by interactions of N-linked and O-linked glycans with HMGB1 box B., PMID:40015632
Exploration and Identification of Potential Biomarkers and Immune Cell Infiltration Analysis in Synovial Tissue of Rheumatoid Arthritis., PMID:39953769
Allogeneic Chimeric Antigen Receptor T-Cell Products Cemacabtagene Ansegedleucel/ALLO-501 in Relapsed/Refractory Large B-Cell Lymphoma: Phase I Experience From the ALPHA2/ALPHA Clinical Studies., PMID:39946666
Results of Cancer and Leukemia Group B 10102 (Alliance), a Phase 1/2 Study., PMID:39916320
EDF1 accelerates ganglioside GD3 accumulation to boost CD52-mediated CD8+ T cell dysfunction in neuroblastoma., PMID:39905449
Alemtuzumab and thrombotic thrombocytopenic purpura: Analysis of an international surveillance database and systematic literature review., PMID:39883995
PerC B-Cells Activation via Thermogenetics-Based CXCL12 Generator for Intraperitoneal Immunity Against Metastatic Disseminated Tumor Cells., PMID:39865939
Soluble CD52 mediates immune suppression by human seminal fluid., PMID:39737172
Sarcoidosis after Alemtuzumab therapy: Is Alemtuzumab posing a threat to its patients?, PMID:39655586
The mononuclear phagocyte system obscures the accurate diagnosis of infected joint replacements., PMID:39563367
Multi-omic characteristics of longitudinal immune profiling after breakthrough infections caused by Omicron BA.5 sublineages., PMID:39536392
Isolation of CD63-positive epididymosomes from human semen and its application in improving sperm function., PMID:39417597
Universal CAR cell therapy: Challenges and expanding applications., PMID:39413693
Cis-interaction between CD52 and T cell receptor complex interferes with CD4+ T cell activation in acute decompensation of cirrhosis., PMID:39276679
A spatiotemporal comparative analysis on tumor immune microenvironment characteristics between neoadjuvant chemotherapy and preoperative immunotherapy for ESCC., PMID:39256364
T-cell dysfunction in CLL is mediated through expression of Siglec-10 ligands CD24 and CD52 on CLL cells., PMID:39042920
Umbilical cord blood T cells can be isolated and enriched by CD62L selection for use in 'off the shelf' chimeric antigen receptor T-cell therapies to widen transplant options., PMID:38988258
Optimizing drug combinations for T-PLL: restoring DNA damage and P53-mediated apoptotic responses., PMID:38941598
CD52/FLAG and CD52/HA Fusion Proteins as Novel Magnetic Cell Selection Markers., PMID:38928060
Integrated Analysis of Single-Cell and Bulk RNA Sequencing Data Reveals Memory-like NK Cell Subset Associated with Mycobacterium tuberculosis Latency., PMID:38391906
Evaluation of the paired-Cas9 nickase and RNA-guided FokI genome editing tools in precise integration of an anti-CD52 bicistronic monoclonal antibody expression construct at Chinese hamster ovary cells 18S rDNA locus., PMID:38342386
Neoadjuvant chemotherapy-induced remodeling of human hormonal receptor-positive breast cancer revealed by single-cell RNA sequencing., PMID:38266804
Surface CD52, CD84, and PTGER2 mark mature PMN-MDSCs from cancer patients and G-CSF-treated donors., PMID:38242120
Neutropenia following immune-depletion, notably CD20 targeting, therapies in multiple sclerosis., PMID:38181696
Alemtuzumab-induced immune-mediated thrombotic thrombocytopenic purpura: A newly described drug-related autoimmune disease., PMID:38112161
CD52 mRNA expression predicts prognosis and response to immune checkpoint blockade in melanoma., PMID:37975535
Novel miRNA-based drug CD5-2 reduces liver tumor growth in diethylnitrosamine-treated mice by normalizing tumor vasculature and altering immune infiltrate., PMID:37795103
Mining of clinical and prognosis related genes in the tumor microenvironment of endometrial cancer: A field synopsis of observational study., PMID:37352078
Base-Edited CAR7 T Cells for Relapsed T-Cell Acute Lymphoblastic Leukemia., PMID:37314354
Overexpression of SIRT6 alleviates apoptosis and enhances cell viability and monoclonal antibody expression in CHO-K1 cells., PMID:37286776
Identification of potential diagnostic biomarkers of atherosclerosis based on bioinformatics strategy., PMID:37173673
Molecular and neuroimmune pharmacology of S1P receptor modulators and other disease-modifying therapies for multiple sclerosis., PMID:37149155
Single-cell RNA sequencing uncovers heterogeneous transcriptional signatures in tumor-infiltrated dendritic cells in prostate cancer., PMID:37144199
Targeted Large-Volume Lymphocyte Removal Using Magnetic Nanoparticles in Blood Samples of Patients with Chronic Lymphocytic Leukemia: A Proof-of-Concept Study., PMID:37108680
An unforeseen reality: Hemophagocytic lymphohistiocytosis following alemtuzumab treatment for a multiple sclerosis., PMID:36965418
T-Cell Prolymphocytic Leukemia With t(X;14)(q28;q11.2): A Clinicopathologic Study of 15 Cases., PMID:36883805
Heterogeneity of B cell lymphopoiesis in patients with premalignant and active myeloma., PMID:36752202
Enhancing progestin therapy via HDAC inhibitors in endometrial cancer., PMID:36504895
Identification of susceptibility modules and hub genes of osteoarthritis by WGCNA analysis., PMID:36468029
Establishment and characterization of the immortalized porcine lung-derived mononuclear phagocyte cell line., PMID:36467652