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Recombinant Human CD52 Protein, C-Fc

Catalog #:   EHD95101 Specific References (49) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: Mammalian Cells
Accession: P31358
Protein length: Met1-Ser61
Overview

Catalog No.

EHD95101

Expression system

Mammalian Cells

Species

Homo sapiens (Human)

Protein length

Met1-Ser61

Predicted molecular weight

30.17 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

P31358

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

Human epididymis-specific protein 5, CDW52, CAMPATH-1 antigen, Cambridge pathology 1 antigen, He5, HE5, Epididymal secretory protein E5, CD52, CDw52

Data Image
  • SDS-PAGE
    SDS PAGE for recombinant Human CD52
References

Expression of NUF2 and CD52 and Their Correlation With Chemotherapy Resistance and Prognosis in Patients With Non-Small Cell Lung Cancer., PMID:40421783

Epstein-Barr virus induces aberrant B cell migration and diapedesis via FAK-dependent chemotaxis pathways., PMID:40389409

Whole-Blood RNA Sequencing Profiling of Patients With Rheumatoid Arthritis Treated With Tofacitinib., PMID:40388487

Investigation of hub-shared genes and regulatory mechanisms of rheumatoid arthritis and atherosclerosis., PMID:40289029

Development and characterization of the novel MYD88 mutated, 6q deleted BCWM.2 cell line for Waldenström macroglobulinaemia., PMID:40254718

Alemtuzumab for haematological malignancies., PMID:40214729

Single-cell sequencing exposes mast cell-derived CD52's anti-tumor action in breast cancer through the IL-6/JAK/STAT3 axis., PMID:40194575

T-cell prolymphocytic leukemia, a case report and review of the literature., PMID:40109866

Single-cell analysis of CD14+CD16+ monocytes identifies a subpopulation with an enhanced migratory and inflammatory phenotype., PMID:40051633

The molecular basis of immunosuppression by soluble CD52 is defined by interactions of N-linked and O-linked glycans with HMGB1 box B., PMID:40015632

Exploration and Identification of Potential Biomarkers and Immune Cell Infiltration Analysis in Synovial Tissue of Rheumatoid Arthritis., PMID:39953769

Allogeneic Chimeric Antigen Receptor T-Cell Products Cemacabtagene Ansegedleucel/ALLO-501 in Relapsed/Refractory Large B-Cell Lymphoma: Phase I Experience From the ALPHA2/ALPHA Clinical Studies., PMID:39946666

Results of Cancer and Leukemia Group B 10102 (Alliance), a Phase 1/2 Study., PMID:39916320

EDF1 accelerates ganglioside GD3 accumulation to boost CD52-mediated CD8+ T cell dysfunction in neuroblastoma., PMID:39905449

Alemtuzumab and thrombotic thrombocytopenic purpura: Analysis of an international surveillance database and systematic literature review., PMID:39883995

PerC B-Cells Activation via Thermogenetics-Based CXCL12 Generator for Intraperitoneal Immunity Against Metastatic Disseminated Tumor Cells., PMID:39865939

Soluble CD52 mediates immune suppression by human seminal fluid., PMID:39737172

Sarcoidosis after Alemtuzumab therapy: Is Alemtuzumab posing a threat to its patients?, PMID:39655586

The mononuclear phagocyte system obscures the accurate diagnosis of infected joint replacements., PMID:39563367

Multi-omic characteristics of longitudinal immune profiling after breakthrough infections caused by Omicron BA.5 sublineages., PMID:39536392

Isolation of CD63-positive epididymosomes from human semen and its application in improving sperm function., PMID:39417597

Universal CAR cell therapy: Challenges and expanding applications., PMID:39413693

Cis-interaction between CD52 and T cell receptor complex interferes with CD4+ T cell activation in acute decompensation of cirrhosis., PMID:39276679

A spatiotemporal comparative analysis on tumor immune microenvironment characteristics between neoadjuvant chemotherapy and preoperative immunotherapy for ESCC., PMID:39256364

T-cell dysfunction in CLL is mediated through expression of Siglec-10 ligands CD24 and CD52 on CLL cells., PMID:39042920

Umbilical cord blood T cells can be isolated and enriched by CD62L selection for use in 'off the shelf' chimeric antigen receptor T-cell therapies to widen transplant options., PMID:38988258

Optimizing drug combinations for T-PLL: restoring DNA damage and P53-mediated apoptotic responses., PMID:38941598

CD52/FLAG and CD52/HA Fusion Proteins as Novel Magnetic Cell Selection Markers., PMID:38928060

Integrated Analysis of Single-Cell and Bulk RNA Sequencing Data Reveals Memory-like NK Cell Subset Associated with Mycobacterium tuberculosis Latency., PMID:38391906

Evaluation of the paired-Cas9 nickase and RNA-guided FokI genome editing tools in precise integration of an anti-CD52 bicistronic monoclonal antibody expression construct at Chinese hamster ovary cells 18S rDNA locus., PMID:38342386

Neoadjuvant chemotherapy-induced remodeling of human hormonal receptor-positive breast cancer revealed by single-cell RNA sequencing., PMID:38266804

Surface CD52, CD84, and PTGER2 mark mature PMN-MDSCs from cancer patients and G-CSF-treated donors., PMID:38242120

Neutropenia following immune-depletion, notably CD20 targeting, therapies in multiple sclerosis., PMID:38181696

Alemtuzumab-induced immune-mediated thrombotic thrombocytopenic purpura: A newly described drug-related autoimmune disease., PMID:38112161

CD52 mRNA expression predicts prognosis and response to immune checkpoint blockade in melanoma., PMID:37975535

Novel miRNA-based drug CD5-2 reduces liver tumor growth in diethylnitrosamine-treated mice by normalizing tumor vasculature and altering immune infiltrate., PMID:37795103

Mining of clinical and prognosis related genes in the tumor microenvironment of endometrial cancer: A field synopsis of observational study., PMID:37352078

Base-Edited CAR7 T Cells for Relapsed T-Cell Acute Lymphoblastic Leukemia., PMID:37314354

Overexpression of SIRT6 alleviates apoptosis and enhances cell viability and monoclonal antibody expression in CHO-K1 cells., PMID:37286776

Identification of potential diagnostic biomarkers of atherosclerosis based on bioinformatics strategy., PMID:37173673

Molecular and neuroimmune pharmacology of S1P receptor modulators and other disease-modifying therapies for multiple sclerosis., PMID:37149155

Single-cell RNA sequencing uncovers heterogeneous transcriptional signatures in tumor-infiltrated dendritic cells in prostate cancer., PMID:37144199

Targeted Large-Volume Lymphocyte Removal Using Magnetic Nanoparticles in Blood Samples of Patients with Chronic Lymphocytic Leukemia: A Proof-of-Concept Study., PMID:37108680

An unforeseen reality: Hemophagocytic lymphohistiocytosis following alemtuzumab treatment for a multiple sclerosis., PMID:36965418

T-Cell Prolymphocytic Leukemia With t(X;14)(q28;q11.2): A Clinicopathologic Study of 15 Cases., PMID:36883805

Heterogeneity of B cell lymphopoiesis in patients with premalignant and active myeloma., PMID:36752202

Enhancing progestin therapy via HDAC inhibitors in endometrial cancer., PMID:36504895

Identification of susceptibility modules and hub genes of osteoarthritis by WGCNA analysis., PMID:36468029

Establishment and characterization of the immortalized porcine lung-derived mononuclear phagocyte cell line., PMID:36467652

Datasheet
$ 480
Product specifications
100 μg 480 1 mg 2880

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For research use only. Not for human or drug use.

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Recombinant Human CD52 Protein, C-Fc [EHD95101]
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