Catalog No.
YHD92901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Val274
Predicted molecular weight
33.40 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P31150
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Oligophrenin-2, Rab GDP dissociation inhibitor alpha, XAP4, Guanosine diphosphate dissociation inhibitor 1, GDIL, GDI1, RABGDIA, Rab GDI alpha, Protein XAP-4, OPHN2, GDI-1
The phosphomimetic Rab10 T73D mutation in mice leads to postnatal lethality and aberrations in neuronal development., PMID:40203954
Gastrodin Mitigates Ketamine-Induced Inhibition of F-Actin Remodeling and Cell Migration by Regulating the Rho Signaling Pathway., PMID:40149625
[Characterization of a Rho GDP dissociation inhibitor gene OsRhoGDI1 from rice]., PMID:39467748
Novel insights into whey protein among Yak, Yellow Cattle, and Cattle-Yak milk., PMID:38681228
Comparative proteomics reveals different protein expression in platelets in patients with alcoholic liver cirrhosis., PMID:38279183
ECM1-associated miR-1260b promotes osteogenic differentiation by targeting GDI1., PMID:38266317
GDP dissociation inhibitor 1 (GDI1) attenuates β-amyloid-induced neurotoxicity in Alzheimer's diseases., PMID:38013121
Molecular dynamics simulations reveal the inhibition mechanism of Cdc42 by RhoGDI1., PMID:37286854
Renal FGF23 signaling depends on redox protein Memo1 and promotes orthovanadate-sensitive protein phosphotyrosyl phosphatase activity., PMID:36434320
RNF115 Inhibits the Post-ER Trafficking of TLRs and TLRs-Mediated Immune Responses by Catalyzing K11-Linked Ubiquitination of RAB1A and RAB13., PMID:35343654
The Pseudo-Natural Product Rhonin Targets RHOGDI., PMID:35170181
Differential Association of 4E-BP2-Interacting Proteins Is Related to Selective Delayed Neuronal Death after Ischemia., PMID:34638676
Overexpression of GDP dissociation inhibitor 1 gene associates with the invasiveness and poor outcomes of colorectal cancer., PMID:34515625
Downregulation of miR‑483‑5p inhibits TGF‑β1‑induced EMT by targeting RhoGDI1 in pulmonary fibrosis., PMID:34080651
High-altitude pulmonary edema is aggravated by risk loci and associated transcription factors in HIF-prolyl hydroxylases., PMID:34007987
Utilizing an Animal Model to Identify Brain Neurodegeneration-Related Biomarkers in Aging., PMID:33807010
Inhibiting glycolysis rescues memory impairment in an intellectual disability Gdi1-null mouse., PMID:33309713
Allelic variants between mouse substrains BALB/cJ and BALB/cByJ influence mononuclear cardiomyocyte composition and cardiomyocyte nuclear ploidy., PMID:32371981
A toxic palmitoylation of Cdc42 enhances NF-κB signaling and drives a severe autoinflammatory syndrome., PMID:32283203
A helitron-induced RabGDIα variant causes quantitative recessive resistance to maize rough dwarf disease., PMID:31980630
Computational design of chemogenetic and optogenetic split proteins., PMID:30279442
Moderate-Intensity Exercise Induces Neurogenesis and Improves Cognition in Old Mice by Upregulating Hippocampal Hippocalcin, Otub1, and Spectrin-α., PMID:30091036
The phosphomimetic mutation of syndecan-4 binds and inhibits Tiam1 modulating Rac1 activity in PDZ interaction-dependent manner., PMID:29121646
Regulation of NOTCH signaling by RAB7 and RAB8 requires carboxyl methylation by ICMT., PMID:29051265
Monitoring the response of urothelial precancerous lesions to Bacillus Calmette-Guerin at the proteome level in an in vivo rat model., PMID:28916862
Exome sequencing identifies a novel mutation of the GDI1 gene in a Chinese non-syndromic X-linked intellectual disability family., PMID:28863211
Involvement of SchRabGDI1 from Solanum chilense in endocytic trafficking and tolerance to salt stress., PMID:28818364
Altered fronto-striatal functions in the Gdi1-null mouse model of X-linked Intellectual Disability., PMID:28057534
Innate immunity kinase TAK1 phosphorylates Rab1 on a hotspot for posttranslational modifications by host and pathogen., PMID:27482120
Antipsychotic drugs induce cell cytoskeleton reorganization in glial and neuronal cells via Rho/Cdc42 signal pathway., PMID:27302765
Rab13 Traffics on Vesicles Independent of Prenylation., PMID:26969162
Calsyntenin 1-mediated trafficking of axon guidance receptors regulates the switch in axonal responsiveness at a choice point., PMID:26839361
A Sensitized Screen for Genes Promoting Invadopodia Function In Vivo: CDC-42 and Rab GDI-1 Direct Distinct Aspects of Invadopodia Formation., PMID:26765257
MERTK signaling in the retinal pigment epithelium regulates the tyrosine phosphorylation of GDP dissociation inhibitor alpha from the GDI/CHM family of RAB GTPase effectors., PMID:26283020
RabGDIα is a negative regulator of interferon-γ-inducible GTPase-dependent cell-autonomous immunity to Toxoplasma gondii., PMID:26240314
Identification of novel phosphatidic acid-binding proteins in the rat brain., PMID:25863174
Global cellular responses to β-methyl-amino-L-alanine (BMAA) by olfactory ensheathing glial cells (OEC)., PMID:25797319
Tumor-specific mutations in low-frequency genes affect their functional properties., PMID:25694352
Protein tyrosine phosphatase-PEST and β8 integrin regulate spatiotemporal patterns of RhoGDI1 activation in migrating cells., PMID:25666508
Bioinformatics analysis of Rab GDP dissociation inhibitor beta and its expression in non-small cell lung cancer., PMID:25367783
Identification of the novel autoantigen candidate Rab GDP dissociation inhibitor alpha in isolated adrenocorticotropin deficiency., PMID:25346144
[Effects of extracts of Prunella Vulgaris L. on proteome of human lung adenocarcinoma cell line A549]., PMID:25331476
Levels of the Rab GDP dissociation inhibitor (GDI) are altered in the prenatal restrain stress mouse model of schizophrenia and are differentially regulated by the mGlu2/3 receptor agonists, LY379268 and LY354740., PMID:25063582
Liposome reconstitution and modulation of recombinant prenylated human Rac1 by GEFs, GDI1 and Pak1., PMID:25014207
Comparative proteomic analysis of anti-cancer mechanism by periplocin treatment in lung cancer cells., PMID:24685647
Clinical impacts of genomic copy number gains at Xq28., PMID:27081496
Screening and identification of dynamin-1 interacting proteins in rat brain synaptosomes., PMID:24211660
Membrane extraction of Rab proteins by GDP dissociation inhibitor characterized using attenuated total reflection infrared spectroscopy., PMID:23898197
Alteration of proteomic profiles in PBMC isolated from patients with Fabry disease: preliminary findings., PMID:23385635
αvβ8 integrin interacts with RhoGDI1 to regulate Rac1 and Cdc42 activation and drive glioblastoma cell invasion., PMID:23283986
For research use only. Not for human or drug use.
