Catalog No.
YHD92201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp185-Thr281
Predicted molecular weight
38.18 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P30968
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
GnRH-R, GRHR, GnRH receptor, Gonadotropin-releasing hormone receptor, GNRHR
The effects of GnRH analogues on endometrial receptivity: a comprehensive study., PMID:40347372
Influences of non-nutritive sweeteners on sweet taste receptors and reproductive hormone signaling in guinea pigs., PMID:40334972
Prenatal genistein exposure in rats affects pubertal onset and serum reproductive hormone levels in male offsprings via the hypothalamic-pituitary-gonadal axis., PMID:40320066
Characterization of a direct role of GnRHs in the control of spermiogenesis and steroidogenesis in the small-spotted catshark Scyliorhinus canicula., PMID:40254036
Inducing Targeted, Caspase-Independent Apoptosis with New Chimeric Proteins for Treatment of Solid Cancers., PMID:40227697
Therapeutic potential of GNRHR analogs and SRC/FAK inhibitors to counteract tumor growth and metastasis in breast cancer., PMID:40189112
Chronic intermittent hypoxia modulates corneal fibrotic markers and inflammatory cytokine expression in a sex-dependent manner., PMID:40139640
Modulation of Gonadotropin-Releasing Hormone Receptor Improves Voiding Hyperreflexia and Detrusor Sphincter Dyssynergia in Male Rats With Severe Spinal Cord Injury., PMID:40095413
A Developmental Gene Expression Atlas Reveals Novel Biological Basis of Complex Phenotypes in Sheep., PMID:40037845
GnRHR inhibits the malignant progression of triple-negative breast cancer by upregulating FOS and IFI44L., PMID:39999929
Neuropeptide Y at the crossroads of male reproductive functions in a seasonally breeding reptile, Hemidactylus flaviviridis., PMID:39971152
Impact of copper nanoparticles (CuNPs) on hypothalamic GnRH and pituitary gonadotropins secretions in a male mouse: An immunohistochemical study., PMID:39954793
Reduction in minipubertal gonadotropin levels alters reproductive lifespan and ovarian follicular loss in female mice., PMID:39948193
Innovative Hybrid Nanocarriers of GnRH Peptide-Modified Chitosan-Coated Lipid Nanoparticles as a Targeted Chemotherapy for Reproductive-Related Cancers., PMID:39895038
Ultrasmall Au-GRHa Nanosystem for FL/CT Dual-Mode Imaging-Guided Targeting Photothermal Therapy of Ovarian Cancer., PMID:39825800
Expression of GnRH, Kisspeptin, and Their Specific Receptors in the Ovary and Uterus in Deslorelin-Treated Late-Prepubertal Bitches., PMID:39728931
Gonadotropin-releasing hormone II and its receptor regulate motility, morphology, and kinematics of porcine spermatozoa in vitro., PMID:39667624
Estradiol affects the expression of essential molecular factors involved in luteinizing hormone secretion in the plains vizcacha., PMID:39551248
Novel non-peptide uracil-derived human gonadotropin-releasing hormone receptor antagonists., PMID:39342681
Aberrant hormone receptors regulate a wide spectrum of endocrine tumors., PMID:39326429
Cytotoxic Activity of Novel GnRH Analogs Conjugated with Mitoxantrone in Ovarian Cancer Cells., PMID:39274973
Homozygous mutation of KISS1 receptor (KISS1R) gene identified in a Chinese patient with congenital hypogonadotropic hypogonadism (CHH): case report and literature review., PMID:39262158
Identification of Environmental Compounds That May Trigger Early Female Puberty by Activating Human GnRHR and KISS1R., PMID:39254333
Eicosatrienoic acid inhibits estradiol synthesis through the CD36/FOXO1/CYP19A1 signaling pathway to improve PCOS in mice., PMID:39236935
Identification and Functional Analysis of Adipokinetic Hormone Receptor in Ostrinia furnacalis Guenée Larvae Parasitized by Macrocentrus cingulum., PMID:39190556
Genome sequencing reveals novel causative structural and single nucleotide variants in Pakistani families with congenital hypogonadotropic hypogonadism., PMID:39143522
The role of AdipoQ on proliferation, apoptosis, and hormone Secretion in chicken primary adenohypophysis cells., PMID:39142032
Effect of active immunization with OPN5 on follicular development and egg production in quail under different photoperiods., PMID:39116655
Divergent folding-mediated epistasis among unstable membrane protein variants., PMID:39078397
Genome sequencing projects reveal new insights into the mammalian Gonadotropin-releasing Hormone II system., PMID:39041341
[Regulating effect of Gegen Decoction on hypothalamic-pituitary-ovarian axis in mice with primary dysmenorrhea]., PMID:39041091
Variety of genetic defects in GnRH and hypothalamic-pituitary signaling and development in normosmic patients with IHH., PMID:39010903
Repurposing GnRH-A as a Near-Infrared Fluorescent Probe for Diagnosis and Surgical Navigation of Breast Cancer Tumors and Metastases., PMID:38995618
Does the activation of sea bass GnIH receptor modulate GnRH receptor signaling?, PMID:38969290
Growth hormone increase by luteinizing hormone-releasing hormone reflects gonadotroph-related characteristics in acromegaly., PMID:38954291
[Toxicity of bisphenol S on human normal ovarian epithelial cells mediated by ERβ-MAPK signaling pathway]., PMID:38839586
The corrective role of superparamagnetic iron oxide nanoparticles for the genes controlling hypothalamus-pituitary-testis-axis in male obesity-associated secondary hypogonadism., PMID:38633156
Reproductive and transgenerational toxicity of bisphenol S exposure in pregnant rats: Insights into hormonal imbalance and steroid biosynthesis pathway disruption., PMID:38614345
Diverse genetic causes of amenorrhea in an ethnically homogeneous cohort and an evolving approach to diagnosis., PMID:38521400
Single microcystin exposure impairs the hypothalamic-pituitary-gonadal axis at different levels in female rats., PMID:38490633
Effect of Caffeine on the Inflammatory-Dependent Changes in the GnRH/LH Secretion in a Female Sheep Model., PMID:38473910
Disruption of gonadotropin hormone biosynthesis by parabens: A potential development and reproduction-associated adverse outcome pathway., PMID:38458526
Evaluating conserved domains and motifs of decapod gonadotropin-releasing hormone G protein-coupled receptor superfamily., PMID:38444586
Functional GnRH receptor signaling regulates striatal cholinergic neurons in neonatal but not in adult mice., PMID:38348415
Social isolation and aggression training lead to escalated aggression and hypothalamus-pituitary-gonad axis hyperfunction in mice., PMID:38337026
The effect of gonadotropin-inhibitory hormone on steroidogenesis and spermatogenesis by acting through the hypothalamic-pituitary-testis axis in mice., PMID:38285410
Characterization of reproductive hormones and related gene expression in the hypothalamus and pituitary gland in the egg-laying interval in White King pigeon., PMID:38228063
Isothiazolinone Disrupts Reproductive Endocrinology by Targeting the G-Protein-Coupled Receptor Signaling., PMID:38166396
Identification of a valuable gene network for the diagnosis and treatment of non-obstructive azoospermia: in-silico analyses - experimental research., PMID:38098601
Targeted Imaging of Endometriosis and Image-Guided Resection of Lesions Using Gonadotropin-Releasing Hormone Analogue-Modified Indocyanine Green., PMID:38089464
For research use only. Not for human or drug use.
