Catalog No.
YHD91301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg18-Ser517
Predicted molecular weight
57.59 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P30837
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Aldehyde dehydrogenase family 1 member B1, Aldehyde dehydrogenase X, mitochondrial, ALDH5, ALDH1B1, ALDHX, Aldehyde dehydrogenase 5
The role of mitochondrial dysfunction in the pathogenesis of atherosclerosis: A new exploration from bioinformatics analysis., PMID:40441253
Comparative analysis of translatomics and transcriptomics in the longissimus dorsi muscle of Luchuan and Duroc pigs., PMID:40100799
Spatial Metabolomics and Transcriptomics Reveal Metabolic Reprogramming and Cellular Interactions in Nasopharyngeal Carcinoma with High PD-1 Expression and Therapeutic Response., PMID:40083932
Transcriptomic alterations in APP/PS1 mice astrocytes lead to early postnatal axon initial segment structural changes., PMID:39485512
Protective Effect and Mechanism of L-Theanine on Acute Alcoholic Liver Injury in Mice., PMID:39468986
Hepatocyte-specific NR5A2 deficiency induces pyroptosis and exacerbates non-alcoholic steatohepatitis by downregulating ALDH1B1 expression., PMID:39438459
Exploring the Role and Pathophysiological Significance of Aldehyde Dehydrogenase 1B1 (ALDH1B1) in Human Lung Adenocarcinoma., PMID:39408636
Modeling alcohol-associated liver disease in humans using adipose stromal or stem cell-derived organoids., PMID:38749443
A novel prognostic signature based on cancer stemness and metabolism-related genes for cervical squamous cell carcinoma and endocervical adenocarcinoma., PMID:38656879
Genetic architecture of alcohol consumption identified by a genotype-stratified GWAS and impact on esophageal cancer risk in Japanese people., PMID:38277453
The aldehyde dehydrogenase ALDH1B1 exerts antiviral effects through the aggregation of the adaptor MAVS., PMID:38194477
The impact of dietary Laminaria digitata and alginate lyase supplementation on the weaned piglet liver: A comprehensive proteomics and metabolomics approach., PMID:38151157
Impaired bone morphogenetic protein signaling pathways disrupt decidualization in endometriosis., PMID:37790548
Multi-omics profiling reveals cellular pathways and functions regulated by ALDH1B1 in colon cancer cells., PMID:37716420
Acetaldehyde and defective mismatch repair increase colonic tumours in a Lynch syndrome model with Aldh1b1 inactivation., PMID:37395714
Associations of alcohol intake with subclinical carotid atherosclerosis in 22,000 Chinese adults., PMID:37392542
An integrative analysis of the tumor suppressors and oncogenes from sexual dimorphism and gene expression alteration features in thyroid cancer., PMID:37355885
Genomic variants and inferred biological processes in multiplex families with Tourette syndrome., PMID:37208127
Tibetan medicine Liuwei Muxiang pills (LWMX pills) effectively protects mice from chronic non-atrophic gastritis., PMID:37167846
Brain-wide transcriptome-based metabolic alterations in Parkinson's disease: human inter-region and human-experimental model correlations., PMID:36928892
Proteomic analysis of spinal cord tissue in a rat model of cancer-induced bone pain., PMID:36545122
A noncanonical function of EIF4E limits ALDH1B1 activity and increases susceptibility to ferroptosis., PMID:36274088
Natural shikonin and acetyl-shikonin improve intestinal microbial and protein composition to alleviate colitis-associated colorectal cancer., PMID:35952517
Targeting ALDH1B1 in colorectal cancer., PMID:35879559
Aldehyde Dehydrogenase 1B1 Is Implicated in DNA Damage Response in Human Colorectal Adenocarcinoma., PMID:35805102
Targeting colorectal cancer with small-molecule inhibitors of ALDH1B1., PMID:35788181
Transcriptomic and Proteomic Analysis of CRISPR/Cas9-Mediated ARC-Knockout HEK293 Cells., PMID:35562887
Effect of different types of muscle activity on the gene and protein expression of ALDH family members in C57BL/6J mouse skeletal muscle., PMID:35439425
AMBRA1 Negatively Regulates the Function of ALDH1B1, a Cancer Stem Cell Marker, by Controlling Its Ubiquitination., PMID:34769507
Investigation of Association of Rare, Functional Genetic Variants With Heavy Drinking and Problem Drinking in Exome Sequenced UK Biobank Participants., PMID:33893496
Aldehyde dehydrogenase 1B1 is a potential marker of colorectal tumors., PMID:33438176
Aldehyde Dehydrogenase 1B1 Is Associated with Altered Cell Morphology, Proliferation, Migration and Chemosensitivity in Human Colorectal Adenocarcinoma Cells., PMID:33419031
MicroRNA-761 suppresses tumor progression in osteosarcoma via negatively regulating ALDH1B1., PMID:33035586
Interplay between APC and ALDH1B1 in a newly developed mouse model of colorectal cancer., PMID:33007288
Proteomic analysis of liver in diet-induced Hyperlipidemic mice under Fructus Rosa roxburghii action., PMID:32927110
Identification and Validation of Novel Serum Autoantibody Biomarkers for Early Detection of Colorectal Cancer and Advanced Adenoma., PMID:32793472
TMT-labeled quantitative proteomic analyses on the longissimus dorsi to identify the proteins underlying intramuscular fat content in pigs., PMID:31881348
Aldh1b1 expression defines progenitor cells in the adult pancreas and is required for Kras-induced pancreatic cancer., PMID:31548432
Protein Methyltransferase Inhibition Decreases Endocrine Specification Through the Upregulation of Aldh1b1 Expression., PMID:30681750
Different morphological structures of breast tumors demonstrate individual drug resistance gene expression profiles., PMID:30285010
The murine hepatic sequelae of long-term ethanol consumption are sex-specific and exacerbated by Aldh1b1 loss., PMID:29859945
Alcohol Metabolism in the Progression of Human Nonalcoholic Steatohepatitis., PMID:29718361
Influence of maternal and own genotype at tanning dependence-related SNPs on sun exposure in childhood., PMID:29649967
Integrative Pathway Analysis of Genes and Metabolites Reveals Metabolism Abnormal Subpathway Regions and Modules in Esophageal Squamous Cell Carcinoma., PMID:28937628
Aldehyde dehydrogenase 1B1: a novel immunohistological marker for colorectal cancer., PMID:28881356
Aldehyde dehydrogenase 1 (ALDH1) isoform expression and potential clinical implications in hepatocellular carcinoma., PMID:28792511
Genetic variants in ALDH1B1 and alcohol dependence risk in a British and Irish population: A bioinformatic and genetic study., PMID:28594837
Taxotere-induced elevated expression of IL8 in carcinoma-associated fibroblasts of breast invasive ductal cancer., PMID:28454334
Neuroserpin polymers cause oxidative stress in a neuronal model of the dementia FENIB., PMID:28363799
Metabolomic mechanisms of gypenoside against liver fibrosis in rats: An integrative analysis of proteomics and metabolomics data., PMID:28291813