Catalog No.
YHD91001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu13-Leu252
Predicted molecular weight
29.56 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P30740
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ELANH2, Peptidase inhibitor 2, Serpin B1, SERPINB1, MNEI, M/NEI, EI, LEI, PI2, Monocyte/neutrophil elastase inhibitor, PI-2, Leukocyte elastase inhibitor
Proteomic Analysis of Transbronchial Biopsies to Discover Novel Biomarkers for Early Identification of Chronic Lung Allograft Dysfunction., PMID:40371053
Identification of exosome-related SERPINB1 as a novel predictor for tumor immune microenvironment and clinical outcomes in ovarian cancer., PMID:40155942
Effects of periodontal disease on the proteomic profile of the periodontal ligament., PMID:39800186
SerpinB1 targeting safeguards against pathological cardiac hypertrophy and remodelling by suppressing cardiomyocyte pyroptosis and inflammation initiation., PMID:39688818
Increased circulating serpinB1 levels in children with overweight/obesity are associated with obesity-related parameters: a cross‑sectional study., PMID:39578813
An Equine Protein Atlas Highlights Synovial Fluid Proteome Dynamics during Experimentally LPS-Induced Arthritis., PMID:39395021
Beta2-Adrenergic Stimulation Induces Resistance Training-Like Adaptations in Human Skeletal Muscle: Potential Role of KLHL41., PMID:39366923
Exogenous serpin B1 restricts immune complex-mediated NET formation via inhibition of a chymotrypsin-like protease and enhances microbial phagocytosis., PMID:38971315
Identification of postnatal development dependent genes and proteins in porcine epididymis., PMID:38049726
Integrative bioinformatics analysis of biomarkers and pathways for exploring the mechanisms and molecular targets associated with pyroptosis in type 2 diabetes mellitus., PMID:38034011
SERPINB1 promotes Senecavirus A replication by degrading IKBKE and regulating the IFN pathway via autophagy., PMID:37811994
Methylation-Regulated Long Non-Coding RNA Expression in Ulcerative Colitis., PMID:37445676
SerpinB1 is required for Rev-erbα-mediated protection against acute lung injury induced by lipopolysaccharide-in mice., PMID:37350044
Systematic druggable genome-wide Mendelian randomisation identifies therapeutic targets for Alzheimer's disease., PMID:37349091
Diagnostic and predictive values of pyroptosis-related genes in sepsis., PMID:36817458
Oxidized mitochondrial DNA induces gasdermin D oligomerization in systemic lupus erythematosus., PMID:36797275
A proteomic analysis of NETosis in trauma: Emergence of serpinB1 as a key player., PMID:36730076
Association between circulating SerpinB1 levels and insulin sensitivity in Japanese with type 2 diabetes: A single-center, cross-sectional, observational study., PMID:36331940
From Bowen disease to cutaneous squamous cell carcinoma: eight markers were verified from transcriptomic and proteomic analyses., PMID:36085041
Expression of Eosinophilic Subtype Markers in Patients with Kawasaki Disease., PMID:36077487
Predictive value of common genetic variants in idiopathic pulmonary fibrosis survival., PMID:35986225
Dietary Inclusion of Dried Chicory Root Affects Cecal Mucosa Proteome of Nursery Pigs., PMID:35804609
Comparative Proteome Profiling of Saliva Between Estrus and Non-Estrus Stages by Employing Label-Free Quantitation (LFQ) and Tandem Mass Tag (TMT)-LC-MS/MS Analysis: An Approach for Estrus Biomarker Identification in Bubalus bubalis., PMID:35754844
Multi-omics analysis of the cervical epithelial integrity of women using depot medroxyprogesterone acetate., PMID:35533147
Generation of resolving memory neutrophils through pharmacological training with 4-PBA or genetic deletion of TRAM., PMID:35418110
Serpin Signatures in Prion and Alzheimer's Diseases., PMID:35416570
SERPINB1 overexpression protects myocardial damage induced by acute myocardial infarction through AMPK/mTOR pathway., PMID:35291946
Proteomic profiling reveals engineered chitosan nanoparticles mediated cellular crosstalk and immunomodulation for therapeutic application in apical periodontitis., PMID:34938914
TWEAK functions with TNF and IL-17 on keratinocytes and is a potential target for psoriasis therapy., PMID:34797693
Serpinb1a suppresses osteoclast formation., PMID:33997318
PMMA-Based Continuous Hemofiltration Modulated Complement Activation and Renal Dysfunction in LPS-Induced Acute Kidney Injury., PMID:33868226
Cathepsin L regulates pathogenicCD4 T cells in experimental autoimmune encephalomyelitis., PMID:33540247
Forkhead box protein O1 (FoxO1) /SERPINB1 ameliorates ROS production in diabetic nephropathy., PMID:33473269
New emerging roles of the novel hepatokine SERPINB1 in type 2 diabetes mellitus: Crosstalk with β-cell dysfunction and dyslipidemia., PMID:33326860
The transcriptomic profiling of SARS-CoV-2 compared to SARS, MERS, EBOV, and H1N1., PMID:33301474
Serpinb1a Is Dispensable for the Development and Cytokine Response of Invariant Natural Killer T Cell Subsets., PMID:33262755
Sunitinib decreases the expression of KRT6A and SERPINB1 in 3D human epidermal models., PMID:33135264
A Novel SERPINB1 Single-Nucleotide Polymorphism Associated With Glycemic Control and β-Cell Function in Egyptian Type 2 Diabetic Patients., PMID:32903749
Integrative mRNA/miRNA expression analysis in healing human gingiva., PMID:32857863
Genetic variants modulate gene expression statin response in human lymphoblastoid cell lines., PMID:32787775
SerpinB1 expression in Th17 cells depends on hypoxia-inducible factor 1-alpha., PMID:32717567
Proteomic analysis reveals the protective effects of emodin on severe acute pancreatitis induced lung injury by inhibiting neutrophil proteases activity., PMID:32244009
Expression and purification of recombinant human serpin B1 yields novel molecules with altered protease inhibitory activities: Functional implications., PMID:32044416
Proteomic Profiling of the ECM of Xenograft Breast Cancer Metastases in Different Organs Reveals Distinct Metastatic Niches., PMID:32019869
Altered platelet proteome in lupus anticoagulant (LA)-positive patients-protein disulfide isomerase and NETosis as new players in LA-related thrombosis., PMID:31956273
piR-39980 promotes cell proliferation, migration and invasion, and inhibits apoptosis via repression of SERPINB1 in human osteosarcoma., PMID:31879982
Neutrophil Elastase Inhibitors Suppress Oxidative Stress in Lung during Liver Transplantation., PMID:31871555
WNT gene polymorphisms and predisposition to apical periodontitis., PMID:31831777
SerpinB1 promotes the proliferation of porcine pancreatic stem cells through the STAT3 signaling pathway., PMID:31785377
SerpinB1 controls encephalitogenic T helper cells in neuroinflammation., PMID:31548399
For research use only. Not for human or drug use.
