Catalog No.
YHD89801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Tyr35-Leu357
Predicted molecular weight
40.08 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P30533
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
A2MRAP, Alpha-2-macroglobulin receptor-associated protein, Alpha-2-MRAP, Low density lipoprotein receptor-related protein-associated protein 1, RAP, LRPAP1
TEIPP-vaccination in checkpoint-resistant non-small cell lung cancer: a first-in-human phase I/II dose-escalation study., PMID:40436854
Proteomic analysis reveals LRPAP1 as a key player in the micropapillary pattern metastasis of lung adenocarcinoma., PMID:38226250
LRPAP1 is released from activated microglia and inhibits microglial phagocytosis and amyloid beta aggregation., PMID:38035103
Secreted LRPAP1 binds and triggers IFNAR1 degradation to facilitate virus evasion from cellular innate immunity., PMID:37743411
Peripheral Blood DNA Methylation Signatures and Response to Tofacitinib in Moderate-to-severe Ulcerative Colitis., PMID:37526299
Integrated Analysis of miRNA and mRNA Regulation Network in Hypertension., PMID:37165183
Genome-wide identification of RNA modification-related single nucleotide polymorphisms associated with rheumatoid arthritis., PMID:36973646
The Genetic Confirmation and Clinical Characterization of LOXL3-Associated MYP28: A Common Type of Recessive Extreme High Myopia., PMID:36917121
Lrpap1 (RAP) Inhibits Proximal Tubule Clathrin Mediated and Clathrin Independent Endocytosis, Ameliorating Renal Aminoglycoside Nephrotoxicity., PMID:36848531
Lrpap1 deficiency leads to myopia through TGF-β-induced apoptosis in zebrafish., PMID:36261846
Assessment of endocytic traffic and Ocrl function in the developing zebrafish neuroepithelium., PMID:35979861
Genome-wide identification of copy number variation and association with fat deposition in thin and fat-tailed sheep breeds., PMID:35614300
The relationship of ADAMTSL2 and LRPAP1 gene methylation level with rheumatoid arthritis activity., PMID:34936547
Identification of intracellular glycosaminoglycan-interacting proteins by affinity purification mass spectrometry., PMID:34472763
Generation of a homozygous LRPAP1 knockout human embryonic stem cell line (FDCHDPe009-B) by CRISPR/Cas9 system., PMID:34469777
Cross-presentation of a TAP-independent signal peptide induces CD8 T immunity to escaped cancers but necessitates anchor replacement., PMID:34142235
Genetic testing results of children suspected to have Stickler syndrome type collagenopathy after ocular examination., PMID:33951325
LRPAP1 autoantibodies in mantle cell lymphoma are associated with superior outcome., PMID:33513604
Serum anti-LRPAP1 is a common biomarker for digestive organ cancers and atherosclerotic diseases., PMID:32939876
Rhegmatogenous Retinal Detachment in Nonsyndromic High Myopia Associated with Recessive Mutations in LRPAP1., PMID:31607522
Enzyme replacement therapy with recombinant pro-CTSD (cathepsin D) corrects defective proteolysis and autophagy in neuronal ceroid lipofuscinosis., PMID:31282275
Identification of non-mutated neoantigens presented by TAP-deficient tumors., PMID:30115740
LRPAP1 is a frequent proliferation-inducing antigen of BCRs of mantle cell lymphomas and can be used for specific therapeutic targeting., PMID:29955130
lrpap1 as a specific marker of proximal pronephric kidney tubuli in Xenopus laevis embryos., PMID:29877571
Differential protein expression in chicken macrophages and heterophils in vivo following infection with Salmonella Enteritidis., PMID:28623956
Mutational screening of SLC39A5, LEPREL1 and LRPAP1 in a cohort of 187 high myopia patients., PMID:28442722
Primate-specific miR-603 is implicated in the risk and pathogenesis of Alzheimer's disease., PMID:26856603
Differential Methylation as a Biomarker of Response to Etanercept in Patients With Rheumatoid Arthritis., PMID:26814849
Prenatal exposure to mixtures of xenoestrogens and genome-wide DNA methylation in human placenta., PMID:26679211
Clinical Characterization of LRPAP1-Related Pediatric High Myopia., PMID:26271838
Detection of mutations in LRPAP1, CTSH, LEPREL1, ZNF644, SLC39A5, and SCO2 in 298 families with early-onset high myopia by exome sequencing., PMID:25525168
Imatinib mesylate stimulates low-density lipoprotein receptor-related protein 1-mediated ERK phosphorylation in insulin-producing cells., PMID:24865476
[Expression of lipoprotein related genes in subchondral bone of early experimental osteoarthritis]., PMID:24754147
APOE and LRPAP1 gene polymorphism and risk of Parkinson's disease., PMID:24504617
Mutations in LRPAP1 are associated with severe myopia in humans., PMID:23830514
Pathway analysis of a genome-wide association study in schizophrenia., PMID:23644028
Role of megalin and the soluble form of its ligand RAP in Cd-metallothionein endocytosis and Cd-metallothionein-induced nephrotoxicity in vivo., PMID:22617749
Prenatal lead levels, plasma amyloid β levels, and gene expression in young adulthood., PMID:22313790
Cholesterol metabolism gene polymorphisms and the risk of biliary tract cancers and stones: a population-based case-control study in Shanghai, China., PMID:21062971
Proteomic analysis of the rat ovary following chronic low-dose exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)., PMID:19492234
LRP-associated protein gene (LRPAP1) and susceptibility to degenerative dementia., PMID:18721259
ACE and LRPAP1 insertion-deletion polymorphisms in a northern Ivory Coast population., PMID:18494379
Lipoprotein receptor associated protein (LRPAP1) insertion/deletion polymorphism: association with gallbladder cancer susceptibility., PMID:17987404
Low-density lipoprotein receptor-related protein-associated protein (LRPAP1) gene IVS5 insertion/deletion polymorphism is not a risk factor for gallstone disease in a Polish population., PMID:17913606
Allelic frequencies at the ACE and LRPAP1 loci suggest age-related relationships in a northern Italian population., PMID:17536759
Characterization of the hepatic disposition of lanoteplase, a rationally designed variant of tissue plasminogen activator in rodents., PMID:17178768
Convergence of genes implicated in Alzheimer's disease on the cerebral cholesterol shuttle: APP, cholesterol, lipoproteins, and atherosclerosis., PMID:16973241
Association of lipoprotein receptor, receptor-associated protein, and metabolizing enzyme gene polymorphisms with gallstone disease: A case-control study., PMID:16837242
Association of low density lipoprotein receptor related protein-associated protein (LRPAP1) gene insertion/deletion polymorphism with gallstone disease., PMID:16704534
Low-density lipoprotein receptor-related protein polymorphisms in patients with elevated factor VIII coagulant activity and venous thrombosis., PMID:16175004
For research use only. Not for human or drug use.
