Catalog No.
YHD87901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Leu289
Predicted molecular weight
35.38 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P30279
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
G1/S-specific cyclin-D2, CCND2
The interaction of HT-2 toxin and Akt1 on gene expression regulation in Kashin-Beck disease pathogenesis., PMID:40449756
The m5C reader Ybx1 regulates embryonic cortical neurogenesis by promoting progenitor cell cycle progression., PMID:40435287
miR-370-3p Inhibited the Proliferation of Sheep Dermal Papilla Cells by Inhibiting the Expression of SMAD4., PMID:40422217
TCF3::ZNF384 induces steroid resistance in B-cell precursor acute lymphoblastic leukemia cells., PMID:40391410
miRNA Differential Expression Profile Analysis and Identification of Potential Key Genes in Active Tuberculosis., PMID:40387517
Optical genome mapping reveals diverse mechanisms of cyclin activation in mantle cell lymphomas lacking IGH::CCND1., PMID:40381701
CD47 expression in classic follicular lymphoma is associated with event-free survival., PMID:40374148
miR-2400 promotes proliferation of bovine skeletal muscle-derived satellite cells by regulating MAGED1 genes expression., PMID:40338441
Daxx Variation as a Potential Predictive Marker of the Therapeutic Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer., PMID:40130316
miR-192-2 Regulates the Proliferation and Apoptosis of Ovarian Granulosa Cells by Targeting IGFBP2 in Zhedong White Geese., PMID:40075946
Comparative analysis of the Mexico City Prospective Study and the UK Biobank identifies ancestry-specific effects on clonal hematopoiesis., PMID:39948438
RNF6 Inhibits Lung Adenocarcinoma Cell Proliferation by Promoting Cyclin D2 Degradation., PMID:39918413
Targeted therapeutic strategy for oral squamous carcinoma using celecoxib-loaded GABA/wheat gluten-alginate nanocarrier hydrogel with glutathione down-regulation and enhanced CCND2-mediated apoptosis., PMID:39909279
The PRC2.1 subcomplex opposes G1 progression through regulation of CCND1 and CCND2., PMID:39903505
Recent Insights Into Wnt-Related tRNA-Derived Fragments (tRFs) in Human Diseases., PMID:39835731
Viral oncogene EBNALP regulates YY1 DNA binding and alters host 3D genome organization., PMID:39747661
[Effect of overexpression of aldehyde dehydrogenase family member A2 on hypertrophic growth and proliferation of cardiomyocytes]., PMID:39722524
Follistatin From hiPSC-Cardiomyocytes Promotes Myocyte Proliferation in Pigs With Postinfarction LV Remodeling., PMID:39692006
Integrative functional screen of genomic loci uncovers CCND2 and its genetic regulatory mechanism in colorectal cancer development., PMID:39680067
Cyclin D1-negative mantle cell lymphoma., PMID:39571691
Cone-rod homeobox transcriptionally activates TCF7 to promote the proliferation of retinal pigment epithelial and retinoblastoma cells in vitro., PMID:39559312
Integrated analysis of transcriptome and proteome reveals a core set of genes involved in osteoblast under oxidative stress., PMID:39522232
Upregulated let-7 expression in the follicular fluid of patients with endometriomas leads to dysfunction of granulosa cells through targeting of IGF1R., PMID:39521729
Association of Genetic Variants at the CDKN1B and CCND2 Loci Encoding p27Kip1 and Cyclin D2 Cell Cycle Regulators with Susceptibility and Clinical Course of Chronic Lymphocytic Leukemia., PMID:39519258
A Necessary Role for Cyclin D2 Induction During Colon Cancer Progression Mediated by L1., PMID:39513917
Effects of PPARG on the proliferation, apoptosis, and estrogen secretion in goat granulosa cells., PMID:39413539
Rare CCND2 (p.Thr280Ile) Variant Associated With Infantile Spasms in a Patient With Megalencephaly-Polymicrogyria-Polydactyly-Hydrocephalus Syndrome., PMID:39395260
Palbociclib in Solid Tumor Patients With Genomic Alterations in the cyclinD-cdk4/6-INK4a-Rb Pathway: Results From National Cancer Institute-Children's Oncology Group Pediatric Molecular Analysis for Therapy Choice Trial Arm I (APEC1621I)., PMID:39298716
Methylation of KSHV vCyclin by PRMT5 contributes to cell cycle progression and cell proliferation., PMID:39255317
Role and Regulatory Mechanism of circRNA_14820 in the Proliferation and Differentiation of Goat Skeletal Muscle Satellite Cells., PMID:39201586
Doxycycline-Mediated Control of Cyclin D2 Overexpression in Human-Induced Pluripotent Stem Cells., PMID:39201401
Chromothripsis-Mediated Small Cell Lung Carcinoma., PMID:39185963
Tet1-mediated 5hmC regulates hippocampal neuroinflammation via wnt signaling as a novel mechanism in obstructive sleep apnoea leads to cognitive deficit., PMID:39169375
Xihuang pills targeting the Warburg effect through inhibition of the Wnt/β-catenin pathway in prostate cancer., PMID:38994113
SLPI overexpression in hMSCs could be implicated in the HSC gene expression profile in AML., PMID:38969699
ErbB3 is required for hyperaminoacidemia-induced pancreatic α cell hyperplasia., PMID:38944125
Trans-Activation of the Coactivator-Associated Arginine Methyltransferase 1 (Carm1) Gene by the Oncogene Product Tax of Human T-Cell Leukemia Virus Type 1., PMID:38927636
KMT2A and chronic inflammation as potential drivers of sporadic parathyroid adenoma., PMID:38888967
LncRNA OIP5-AS1 Upregulates the Cyclin D2 Levels to Promote Metastasis of Breast Cancer by Targeting miR-150-5p., PMID:38888699
[Bioinformatic analysis of CCND2 expression in papillary thyroid carcinoma and its impact on immune infiltration]., PMID:38862457
lncRNA Biomarkers of Glioblastoma Multiforme., PMID:38790894
Circ_0002331 Interacts with ELAVL1 to Improve ox-LDL-Induced Vascular Endothelial Cell Dysfunction via Regulating CCND2 mRNA Stability., PMID:38743320
A de novo Mutation (p.Gln277X) of Cyclin D2 is Responsible for a Child with Megalencephaly-Polymicrogyria-Polydactyly-Hydrocephalus Syndrome., PMID:38700464
DROSHA Regulates Mesenchymal Gene Expression in Wilms Tumor., PMID:38647377
Cellular and Transcriptional Response of Human Astrocytes to Hybrid Protein Materials., PMID:38632900
The PRC2.1 Subcomplex Opposes G1 Progression through Regulation of CCND1 and CCND2., PMID:38562687
Oligo-PROTAC strategy for cell-selective and targeted degradation of activated STAT3., PMID:38384444
Up-regulation of lncRNA WT1-AS ameliorates Aβ-stimulated neuronal injury through modulation of miR-186-5p/CCND2 axis in Alzheimer's disease., PMID:38372094
Identification and verification of feature biomarkers associated with immune cells in recurrent pregnancy loss., PMID:38305600
miR‑146a‑5p and miR‑191‑5p as novel diagnostic marker candidates for ovarian clear cell carcinoma., PMID:38264014