Catalog No.
YHD86701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Val5-Trp233
Predicted molecular weight
27.14 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P30048
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
HBC189, AOP1, Antioxidant protein 1, Peroxiredoxin III, AOP-1, Protein MER5 homolog, Prx-III, Peroxiredoxin-3, Thioredoxin-dependent peroxide reductase, mitochondrial, Thioredoxin-dependent peroxiredoxin 3, PRDX3
MiR-383-5p promotes schistosomiasis-induced liver fibrosis by targeting peroxiredoxin-3., PMID:40462224
Local DIO2 Elevation Is an Adaption in Malformed Cerebrovasculature., PMID:40130314
Histone lactylation protects against sevoflurane-induced cognitive impairment by regulating YTHDF3/PRDX3 mediated microglial pyroptosis in neonatal mice., PMID:40022822
Empagliflozin attenuates renal damage in diabetic nephropathy by modulating mitochondrial quality control via Prdx3-PINK1 pathway., PMID:39983849
Silica Nanoparticles Induce SH-SY5Y Cells Death Via PARP and Caspase Signaling Pathways., PMID:39907903
Aminoguanidine hemisulfate improves mitochondrial autophagy, oxidative stress, and muscle force in Duchenne muscular dystrophy via the AKT/FOXO1 pathway in mdx mice., PMID:39806512
Antioxidant PRDX3 gene therapy protects brain cells and prevents neurodegeneration in an animal model of Parkinson's disease., PMID:39736192
Human mitochondrial peroxiredoxin Prdx3 is dually localized in the intermembrane space and matrix subcompartments., PMID:39591905
Expression of Myeloperoxidase in Patient-Derived Endothelial Colony-Forming Cells-Associations with Coronary Artery Disease and Mitochondrial Function., PMID:39456241
A miR-383-5p Signaling Hub Coordinates the Axon Regeneration Response to Inflammation., PMID:39266301
FXN targeting induces cell death in ovarian cancer stem-like cells through PRDX3-Mediated oxidative stress., PMID:39184439
Cadmium causes spleen toxicity in chickens by regulating mitochondrial unfolded protein response and nuclear receptors response., PMID:39180780
Peroxiredoxin 3 Deficiency Exacerbates DSS-Induced Acute Colitis via Exosomal miR-1260b-Mediated Barrier Disruption and Proinflammatory Signaling., PMID:38970422
Multi-omics revealed anti-fatigue property of polyphenol from areca nut., PMID:38964153
YAP1 inhibits the senescence of alveolar epithelial cells by targeting Prdx3 to alleviate pulmonary fibrosis., PMID:38945958
Mapping Novel Frataxin Mitochondrial Networks Through Protein- Protein Interactions., PMID:38746130
Breathing Air and Living Underwater: Molecular Evolution of Genes Related to Antioxidant Response in Cetaceans and Pinnipeds., PMID:38735005
Activation of the FOXM1/ASF1B/PRDX3 axis confers hyperproliferative and antioxidative stress reactivity to gastric cancer., PMID:38537775
Effects of antioxidant vitamins (A, D, E) and trace elements (Cu, Mn, Se, Zn) administration on gene expression, metabolic, antioxidants and immunological profiles during transition period in dromedary camels., PMID:38481237
Peroxiredoxin 3 has a crucial role in the macrophage polarization by regulating mitochondrial homeostasis., PMID:38431661
Mechanism of KAT2A regulation of H3K36ac in manganese-induced oxidative damage to mitochondria in the nervous system and intervention by curcumin., PMID:38417317
Dexmedetomidine alleviates Hypoxia/reoxygenation-induced mitochondrial dysfunction in cardiomyocytes via activation of Sirt3/Prdx3 pathway., PMID:38407745
IC3D Classification of Corneal Dystrophies-Edition 3., PMID:38359414
Effects of limonin on oxidative stress and early apoptosis in oocytes during in vitro maturation., PMID:38290232
A novel specific ferroptosis marker PRDX3: A hero or a villain in clear-cell renal cell carcinoma?, PMID:38220529
The E3 ubiquitin ligase TRIM39 modulates renal fibrosis induced by unilateral ureteral obstruction through regulating proteasomal degradation of PRDX3., PMID:38195664
USP7-mediated ERβ stabilization mitigates ROS accumulation and promotes osimertinib resistance by suppressing PRDX3 SUMOylation in non-small cell lung carcinoma., PMID:38097136
FOLFIRINOX chemotherapy modulates the peripheral immune landscape in pancreatic cancer: Implications for combination therapies and early response prediction., PMID:37988843
Identification of hyperoxidized PRDX3 as a ferroptosis marker reveals ferroptotic damage in chronic liver diseases., PMID:37863053
LRPPRC regulates malignant behaviors, protects mitochondrial homeostasis, mitochondrial function in osteosarcoma and derived cancer stem-like cells., PMID:37789316
Identification of Candidate Biomarkers of Alzheimer's Disease via Multiplex Cerebrospinal Fluid and Serum Proteomics., PMID:37762527
DDAH1 Protects against Cardiotoxin-Induced Muscle Injury and Regeneration., PMID:37760057
α-Lipoic acid improves mitochondrial biogenesis and dynamics by enhancing antioxidant and inhibiting Wnt/Ca2+ pathway to relieve fluoride-induced hepatotoxic injury., PMID:37739047
Exon Skipping Caused by Noncanonical Splicing Mutation in PRDX3-Related Spinocerebellar Ataxia., PMID:37553955
Pure cerebellar ataxia due to bi-allelic PRDX3 variants including recurring p.Asp202Asn., PMID:37553803
Sirtuin 5 Alleviates Liver Ischemia/Reperfusion Injury by Regulating Mitochondrial Succinylation and Oxidative Stress., PMID:37515421
A PPIX-binding probe facilitates discovery of PPIX-induced cell death modulation by peroxiredoxin., PMID:37355765
Mating modifies the expression of crucial oxidative-reductive transcripts in the pig oviductal sperm reservoir: is the female ensuring sperm survival?, PMID:37351104
Knockdown of circSOD2 ameliorates osteoarthritis progression via the miR-224-5p/PRDX3 axis., PMID:37312219
Melatonin alleviates ovarian function damage and oxidative stress induced by dexamethasone in the laying hens through FOXO1 signaling pathway., PMID:37302326
Natural Antioxidant By-Product Mixture Counteracts the Effects of Aflatoxin B1 and Ochratoxin A Exposure of Piglets after Weaning: A Proteomic Survey on Liver Microsomal Fraction., PMID:37104237
Space Omics and Tissue Response in Astronaut Skeletal Muscle after Short and Long Duration Missions., PMID:36835504
Ablation of Shank1 Protects against 6-OHDA-induced Cytotoxicity via PRDX3-mediated Inhibition of ER Stress in SN4741 Cells., PMID:36797610
Immunomodulatory effects of graded levels of docosahexaenoic acid (DHA) in common carp (Cyprinus carpio) - In vitro and in vivo approaches., PMID:36758658
Mitochondrial DNA and inflammatory proteins are higher in extracellular vesicles from frail individuals., PMID:36710345
NEK6 Regulates Redox Balance and DNA Damage Response in DU-145 Prostate Cancer Cells., PMID:36672191
PRDX3 promotes resistance to cisplatin in gastric cancer cells., PMID:36647961
Peroxiredoxin-3 plays a neuroprotective role in early brain injury after experimental subarachnoid hemorrhage in rats., PMID:36566946
Maternal Gliadin Intake Reduces Oocyte Quality with Chromosomal Aberrations and Increases Embryonic Lethality through Oxidative Stress in a Caenorhabditis elegans Model., PMID:36558561
Dihydromyricetin ameliorates social isolation-induced anxiety by modulating mitochondrial function, antioxidant enzymes, and BDNF., PMID:36532369
For research use only. Not for human or drug use.
