Catalog No.
YHD84701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Leu73-Leu418
Predicted molecular weight
41.31 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P29590
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MYL, Promyelocytic leukemia protein, TRIM19, PML, RNF71, RING finger protein 71, Protein PML, PP8675, Tripartite motif-containing protein 19
A comparison of JC virus assay performance provided with originator and biosimilar natalizumab., PMID:40515643
Beyond the switch to the biosimilar of natalizumab: What is the impact of changing the JCV test?, PMID:40515642
CRISPR antiviral inhibits neurotrophic JC polyomavirus in 2D and 3D culture models through dual-gRNA excision by SaCas9., PMID:40510594
Rapid onset of neurological symptoms in an HIV-positive patient with progressive multifocal leukoencephalopathy: a case report., PMID:40486551
Limiting TDP-43 aggregation by induced recruitment to PML-NB., PMID:40480843
DNA2 and FANCM function in two distinctive pathways in disrupting TERRA R-loops and suppressing replication stress at ALT telomeres., PMID:40475582
PML1-Mediated Feedforward Loop Through PI3K and MAPK Axes Drives Endocrine Resistance., PMID:40463196
TSPO PET in multiple sclerosis: Emerging insights into pathophysiology, prognosis, and treatment monitoring., PMID:40450829
Dimethylarsenic acid (DMA) is the material basis for the oral arsenic realgar in treatment of leukemia., PMID:40449168
Harnessing PD-1-overexpressing macrophage membrane for preparation of lenvatinib-loaded vesicles to boost immunotherapy against HCC recurrence after radiofrequency ablation., PMID:40424831
EBNA1., PMID:40399573
YAP/TAZ: An epitome of tumorigenesis., PMID:40381686
Ubiquitin-SUMO tag-team wrestles acute promyelocytic leukemia., PMID:40343456
Mutation in the Unrearranged PML Allele Confers Resistance to Arsenic Trioxide in Acute Promyelocytic Leukemia., PMID:40330660
Examination of the functions and mechanism of KCP in mediating paclitaxel resistance in cervical squamous carcinoma cells., PMID:40297811
Fast pH-Driven Solubilization Method of Realgar (As4S4) to Reduce the Toxicity of Arsenic [As(III)] for Medicinal Purposes., PMID:40271739
Semirational Design of 4-Hydroxyphenylpyruvate Dioxygenase for Efficient and Regioselective Production of 3-Hydroxy-3-methylbutyrate., PMID:40259890
Progressive multifocal leukoencephalopathy during 4 years of Palbociclib for advanced breast cancer with a history of follicular lymphoma patient., PMID:40259166
Immunophenotypic Profiling of Acute Promyelocytic Leukemia: Insights From a Large Cohort., PMID:40251942
Induced proximity to PML protects TDP-43 from aggregation via SUMO-ubiquitin networks., PMID:40246979
Nuclear SUMOylation and Proteotoxic Stress Responses to Metals with Different Ligand Preferences., PMID:40243484
PML mutants from arsenic-resistant patients reveal SUMO1-TOPORS and SUMO2/3-RNF4 degradation pathways., PMID:40239066
Design and development of highly conserved, HLA-promiscuous T cell multiepitope vaccines against human visceral leishmaniasis., PMID:40230841
Conditional Binding of Arsenic Trioxide (ATO) to Cysteine-Rich Zinc Finger Motifs within RBCC Domain of PML Protein., PMID:40219955
HLA-DR positive acute promyelocytic leukaemia (APML) with cryptic PML::RARA fusion., PMID:40214855
Lateral flow assay-based detection of nuclear fusion oncoprotein: implications for screening of acute promyelocytic leukemia., PMID:40162346
Developmental Dynamics of the Rabbit Cerebellum During Fetal Maturation With Insights into the Role of Radial Glia in Neuronal Development., PMID:40156886
Interspecies Differences in Cytomegalovirus Inhibition by Cardiac Glycosides-A Unique Role of the Alpha3 Isoform of the Na+/K+-ATPase Pump., PMID:40143325
Single-cell transcriptomic and functional studies identify glial state changes and a role for inflammatory RIPK1 signaling in ALS pathogenesis., PMID:40132594
Safety and efficacy of long-term gantenerumab treatment in dominantly inherited Alzheimer's disease: an open-label extension of the phase 2/3 multicentre, randomised, double-blind, placebo-controlled platform DIAN-TU trial., PMID:40120616
T-bet+ CXCR3+ B cells drive hyperreactive B-T cell interactions in multiple sclerosis., PMID:40107244
Ferroptosis-Related Genes Are Effective Markers for Diagnostic Targets of Crohn's Disease., PMID:40084946
Using genetics, genomics, and transcriptomics to identify therapeutic targets in juvenile idiopathic arthritis., PMID:40083163
Detecting Telomeric DNA Damage by Immuno-Telo FISH., PMID:40082354
PML Regulated HIF1AN Ubiquitination and Activated PI3K/AKT Pathway to Promote Bone Marrow Mesenchymal Stem Cells Osteogenic Differentiation., PMID:40059075
SERS-Based Assessment of DNA Methylation for the Evaluation of Measurable Residual Disease in Acute Promyelocytic Leukaemia., PMID:40042091
Microbial Transglutaminase-The Food Additive, a Potential Inducing Factor in Primary Biliary Cholangitis., PMID:40005074
A Perspective on Therapeutic Targeting Against Ubiquitin Ligases to Stabilize Tumor Suppressor Proteins., PMID:40002221
Single-cell multiomics reveals a gene regulatory circuit driving leukemia cell differentiation., PMID:39984714
Distinct leukemogenic mechanism of acute promyelocytic leukemia based on genomic structure of PML::RARα., PMID:39979604
Epithelial miR-149-5p up-regulation is associated with immune evasion in progressive bronchial premalignant lesions., PMID:39975222
Prolonged survival in HIV-associated Progressive Multifocal Leukoencephalopathy treated with Pembrolizumab: a case series on treatment and long-term follow-up., PMID:39971875
Locking the gates of immortality: targeting alternative lengthening of telomeres (ALT) pathways., PMID:39964637
Discovery of myeloid zinc finger (MZF) 1 nuclear bodies., PMID:39954358
Correlation-based nanometric localization using lattice SIM2 and dSTORM in PML nuclear bodies validated by calibration spheres., PMID:39954357
Promyelocytic Leukemia Protein (PML) Regulates Stem Cell Pluripotency Through Novel Sumoylation Targets., PMID:39940913
circAFF2 promotes the development of AML by binding to PML mRNA., PMID:39930271
Sintilimab for treating progressive multifocal leukoencephalopathy caused by human polyomavirus 2 virus infection following allogeneic hematopoietic cell transplantation: a case report., PMID:39898889
Telomeric SUMO level influences the choices of APB formation pathways and ALT efficiency., PMID:39896638
Effectiveness of 6-week dosing of Natalizumab versus continued 4-week treatment for Multiple Sclerosis: An observational registry-based study., PMID:39893751
For research use only. Not for human or drug use.
