Catalog No.
RHP12301
Species reactivity
Human, Mouse, Rat, Monkey
Host species
Mouse
Isotype
IgG2b
Clonality
Monoclonal
Tested applications
IP: 1:20, WB: 1:500-1:1000
Target
hRAD9, DNA repair exonuclease rad9 homolog A, RAD9A, Cell cycle checkpoint control protein RAD9A
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q99638
Applications
IP, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.5% BSA, 0.05% Sodium Azide and 50% Glycerol.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R4D67
Loss of RAD9B impairs early neural development and contributes to the risk for human spina bifida., PMID:31898828
Identification and characterization of a novel nuclear structure containing members of the homologous recombination and DNA damage response pathways., PMID:30553479
Impact of α-targeted radiation therapy on gene expression in a pre-clinical model for disseminated peritoneal disease when combined with paclitaxel., PMID:25268703
Rad9, Rad17, TopBP1 and claspin play essential roles in heat-induced activation of ATR kinase and heat tolerance., PMID:23383325
The RAD9-RAD1-HUS1 (9.1.1) complex interacts with WRN and is crucial to regulate its response to replication fork stalling., PMID:22002307
Reduced mRNA and protein expression of the genomic caretaker RAD9A in primary fibroblasts of individuals with childhood and independent second cancer., PMID:21991345
Rad9 is required for B cell proliferation and immunoglobulin class switch recombination., PMID:20729201
ATR and Rad17 collaborate in modulating Rad9 localisation at sites of DNA damage., PMID:19020305
DNA damage sensor protein hRad9, a novel molecular target for lung cancer treatment., PMID:18949400
Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin., PMID:11799063
The budding yeast Rad9 checkpoint protein is subjected to Mec1/Tel1-dependent hyperphosphorylation and interacts with Rad53 after DNA damage., PMID:9755168
Identification of a mid-anaphase checkpoint in budding yeast., PMID:9015305