Catalog No.
YHD81101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn18-Met302
Predicted molecular weight
34.48 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P29017
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CD1c, CD1C, T-cell surface glycoprotein CD1c
In silico evaluation of the immunogenic profile of lung cancers with SMARCA4 genetic alterations., PMID:40404793
Heat Stress Influences Immunity Through DUSP1 and HSPA5 Mediated Antigen Presentation in Chickens., PMID:40281975
Regulation of in vitro human hematopoietic differentiation by dioxin-like compounds., PMID:40187479
Vaginal Prevotella timonensis Bacteria Enhance HIV-1 Uptake and Differentially Affect Transmission by Distinct Primary Dendritic Cell Subsets., PMID:40071689
A novel monoclonal antibody against human thymic stromal lymphopoietin for the treatment of TSLP-mediated diseases., PMID:39726595
Innate Immune Cell Profiling in Peripheral Blood Mononuclear Cells of Patients with Moyamoya Disease., PMID:39671077
Prevalence of hybrid TLR4+M2 monocytes/macrophages in peripheral blood and lung of systemic sclerosis patients with interstitial lung disease., PMID:39635531
Human genital dendritic cell heterogeneity confers differential rapid response to HIV-1 exposure., PMID:39524443
Establishment of CD1b-restricted immunity to lipid antigens in the pulmonary response to Mycobacterium tuberculosis infection., PMID:39494875
Ex vivo-generated human CD1c+ regulatory B cells by a chemically defined system suppress immune responses and alleviate graft-versus-host disease., PMID:39489917
New insights into the immunomodulatory potential of sialic acid on monocyte-derived dendritic cells., PMID:39487861
Insights into the CD1 lipidome., PMID:39238636
Epithelium/imcDC2 axis facilitates the resistance of neoadjuvant anti-PD-1 in human NSCLC., PMID:39134346
Interaction between microglial cells and CD1C+ B dendritic cells leads to CD8+ T cells depletion during the early stages of renal clear cell carcinoma., PMID:39093774
Imbalance of programmed cell death patterns mediated by dendritic cell subsets in systemic lupus erythematosus and lupus nephritis., PMID:38970507
A randomized phase II clinical trial of stereotactic body radiation therapy (SBRT) and systemic pembrolizumab with or without intratumoral avelumab/ipilimumab plus CD1c (BDCA-1)+/CD141 (BDCA-3)+ myeloid dendritic cells in solid tumors., PMID:38954010
A structural perspective of how T cell receptors recognize the CD1 family of lipid antigen-presenting molecules., PMID:38945451
Dendritic Cell-Related Immune Marker CD1C for Predicting Prognosis and Immunotherapy Opportunities of Lung Adenocarcinoma Patients., PMID:38907868
Exosomes multiplex profiling, a promising strategy for early diagnosis of laryngeal cancer., PMID:38902710
Unifying considerations and evidence of macrophage activation mosaicism through human CSF1R and M1/M2 genes., PMID:38870011
Differences in IDO1+ dendritic cells and soluble CTLA-4 are associated with differential clinical responses to methotrexate treatment in rheumatoid arthritis., PMID:38840915
Integrated Analysis of CD1A Immune Infiltration and Competing Endogenous RNA Networks in COAD., PMID:38751492
The Dysregulation of the Monocyte-Dendritic Cell Interplay Is Associated with In-Hospital Mortality in COVID-19 Pneumonia., PMID:38731010
Comparison of Extracellular Vesicles from Induced Pluripotent Stem Cell-Derived Brain Cells., PMID:38612385
Relationship between Phenotypic Changes of Dendritic Cell Subsets and the Onset of Plateau Phase during Intermittent Interferon Therapy in Patients with CHB., PMID:38582994
cDC2 plasticity and acquisition of a DC3-like phenotype mediated by IL-6 and PGE2 in a patient-derived colorectal cancer organoids model., PMID:38509863
ncRNAs-mediated TIMELESS overexpression in lung adenocarcinoma correlates with reduced tumor immune cell infiltration and poor prognosis., PMID:38261568
Inhibition of CSF-1R and IL-6R prevents conversion of cDC2s into immune incompetent tumor-induced DC3s boosting DC-driven therapy potential., PMID:38242119
Intratumoral administration of the immunologic adjuvant AS01B in combination with autologous CD1c (BDCA-1)+/CD141 (BDCA-3)+ myeloid dendritic cells plus ipilimumab and intravenous nivolumab in patients with refractory advanced melanoma., PMID:38212127
Differential Activation of Splenic cDC1 and cDC2 Cell Subsets following Poxvirus Infection of BALB/c and C57BL/6 Mice., PMID:38201217
A distinct human cell type expressing MHCII and RORγt with dual characteristics of dendritic cells and type 3 innate lymphoid cells., PMID:38109523
Identifying CD1c as a potential biomarker by the comprehensive exploration of tumor mutational burden and immune infiltration in diffuse large B cell lymphoma., PMID:38099311
Bona fide dendritic cells are pivotal precursors for osteoclasts., PMID:38071515
Vedolizumab Efficacy Is Associated With Decreased Intracolonic Dendritic Cells, Not Memory T Cells., PMID:37837660
Multi-omics segregate different transcriptomic impacts of anti-IL-17A blockade on type 17 T-cells and regulatory immune cells in psoriasis skin., PMID:37781383
Human IgMhiCD300a+ B Cells Are Circulating Marginal Zone Memory B Cells That Respond to Pneumococcal Polysaccharides and Their Frequency Is Decreased in People Living with HIV., PMID:37762055
Do antigen-presenting CD1a, CD1b, CD1c, and CD1d molecules bind different self-lipids?, PMID:37730500
CD1 lipidomes reveal lipid-binding motifs and size-based antigen-display mechanisms., PMID:37725977
Saponin-based adjuvants enhance antigen cross-presentation in human CD11c+ CD1c+ CD5- CD163+ conventional type 2 dendritic cells., PMID:37612044
Aberrant phenotype of circulating antigen presenting cells in giant cell arteritis and polymyalgia rheumatica., PMID:37600779
Glucose metabolism and its role in the maturation and migration of human CD1c+ dendritic cells following exposure to BCG., PMID:37475964
Establishment of CD1b-restricted immunity to lipid antigens in the pulmonary response to Mycobacterium tuberculosis infection., PMID:37292852
Transcriptome network analysis implicates CX3CR1-positive type 3 dendritic cells in non-infectious uveitis., PMID:37042831
Impaired Antitumor Immune Response in MYCN-amplified Neuroblastoma Is Associated with Lack of CCL2 Secretion and Poor Dendritic Cell Recruitment., PMID:36923280
Monitoring Blood Immune Cells in Patients with Advanced Small Cell Lung Cancer Undergoing a Combined Immune Checkpoint Inhibitor/Chemotherapy., PMID:36830562
Distribution of DC Subtypes: CD83+, DC-LAMP+, CD1a+, CD1c+, CD123+, and DC-SIGN+ in the Tumor Microenvironment of Endometrial Cancers-Correlation with Clinicopathologic Features., PMID:36768258
CD1C is associated with breast cancer prognosis and immune infiltrates., PMID:36755259
High-expression of the innate-immune related gene UNC93B1 predicts inferior outcomes in acute myeloid leukemia., PMID:36741319
GM-CSF, Flt3-L and IL-4 affect viability and function of conventional dendritic cell types 1 and 2., PMID:36713392
Integrated bioinformatics-based identification of potential diagnostic biomarkers associated with atopic dermatitis., PMID:36686015
For research use only. Not for human or drug use.
