Catalog No.
RHJ65503
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400
Target
CD289, TLR9, Toll-like receptor 9
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9NR96
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3W92
Toll-like receptor 9 (TLR9) expression correlates with cell of origin and predicts clinical outcome in diffuse large B-cell lymphoma., PMID:40437466
Distinct metabolic profiles of circulating plasmacytoid dendritic cells in systemic sclerosis patients stratified by clinical phenotypes., PMID:39972361
CD20 and CD19 promote proliferation driven by the IgM-TLR9-L265P MyD88 complex., PMID:39868594
Serum TLR2 and TLR9 in Prostate Cancer Patients in Relation to EBV Status., PMID:39201739
Essential role of pre-existing humoral immunity in TLR9-mediated type I IFN response to recombinant AAV vectors in human whole blood., PMID:39007143
The Expression of Toll-like Receptors (TLR7 and TLR9) in Class III and Class IV of Recently Diagnosed Lupus Nephritis with 12-Month Follow-Up., PMID:39000140
TLR9 agonism differentially impacts human NK cell-mediated direct killing and antibody-dependent cell-mediated cytotoxicity., PMID:38918496
Tubular expression of Toll-like receptor 9 in lupus and primary membranous nephropathy., PMID:38746965
Cyclical palmitoylation regulates TLR9 signalling and systemic autoimmunity in mice., PMID:38169466
Impact of a TLR9 agonist and broadly neutralizing antibodies on HIV-1 persistence: the randomized phase 2a TITAN trial., PMID:37696935
Disulfide-HMGB1 signals through TLR4 and TLR9 to induce inflammatory macrophages capable of innate-adaptive crosstalk in human liver transplantation., PMID:37567451
Involvement of TLR9 in priming the immune response in oral papillomatosis induced by low-risk HPV., PMID:37518875
MTMR3 risk alleles enhance Toll Like Receptor 9-induced IgA immunity in IgA nephropathy., PMID:37414396
Dual TLR9 and PD-L1 targeting unleashes dendritic cells to induce durable antitumor immunity., PMID:37208130
Sex differences in the percentage of IRF5 positive B cells are associated with higher production of TNF-α in women in response to TLR9 in humans., PMID:36814288
Phase Ib open-label, multicenter study of pixatimod, an activator of TLR9, in combination with nivolumab in subjects with microsatellite-stable metastatic colorectal cancer, metastatic pancreatic ductal adenocarcinoma and other solid tumors., PMID:36634920
Increased macrophage phagocytic activity with TLR9 agonist conjugation of an anti- Borrelia burgdorferi monoclonal antibody., PMID:36396013
The Importance of Toll-like Receptor 9 Expression on Monocytes and Dendritic Cells in the Context of Epstein-Barr Virus Infection in the Immunopathogenesis of Primary Glomerulonephritis., PMID:36233099
A bivalent CMV vaccine formulated with human compatible TLR9 agonist CpG1018 elicits potent cellular and humoral immunity in HLA expressing mice., PMID:35737741
Neoadjuvant Intratumoral Immunotherapy with TLR9 Activation and Anti-OX40 Antibody Eradicates Metastatic Cancer., PMID:35135810
Emerging Concepts in Immune Thrombotic Thrombocytopenic Purpura., PMID:34858410
Overexpression of TLR7 and TLR9 Occurs Before Onset Symptoms In First-Degree Relatives of Rheumatoid Arthritis Patients., PMID:34272096
Association of Herpes simplex virus I&II infections with rs187084 SNP of TLR9 and male infertility., PMID:34216052
A Phase Ib Open-Label, Multicenter Study of Inhaled DV281, a TLR9 Agonist, in Combination with Nivolumab in Patients with Advanced or Metastatic Non-small Cell Lung Cancer., PMID:34108179
Direct and indirect immune effects of CMP-001, a virus-like particle containing a TLR9 agonist., PMID:34083419
Effects of long-term cryopreservation of PBMC on recovery of B cell subpopulations., PMID:34048717
Functional Immunostimulating DNA Materials: The Rising Stars for Cancer Immunotherapy., PMID:33896107
Evaluation of expression of Toll-Like Receptors 7 and 9, proliferation, and cytoskeletal biomarkers in plaque and guttate psoriasis: A pilot morphological study., PMID:33666385
Toll-like receptor signalling in B cells during systemic lupus erythematosus., PMID:33339987
Upregulation of the expression of Toll-like receptor 9 in basophils in patients with allergic rhinitis: An enhanced expression by allergens., PMID:33247440
Activated Human Memory B Lymphocytes Use CR4 (CD11c/CD18) for Adhesion, Migration, and Proliferation., PMID:33133077
Mitochondrial DNA enhance innate immune responses in neuromyelitis optica by monocyte recruitment and activation., PMID:32764561
All-trans retinoic acid increases NF-κB activity in PMA-stimulated THP-1 cells upon unmethylated CpG challenge by enhancing cell surface TLR9 expression., PMID:32638255
The Use of Toll-Like Receptor Agonists in HIV-1 Cure Strategies., PMID:32595636
Elevated EPSTI1 promote B cell hyperactivation through NF-κB signalling in patients with primary Sjögren's syndrome., PMID:32114510
Effect of high mobility group box 1 on Toll-like receptor 9 in B cells in myeloperoxidase-ANCA-associated vasculitis., PMID:31790283
Stimulation of Mononuclear Cells Through Toll-Like Receptor 9 Induces Release of Microvesicles Expressing Double-Stranded DNA and Galectin 3-Binding Protein in an Interferon-α-Dependent Manner., PMID:31681284
Hepatitis B Vaccination and Waning Hepatitis B Immunity in Persons Living with HIV., PMID:31468298
Complement Receptor Type 1 (CR1, CD35), the Inhibitor of BCR-Mediated Human B Cell Activation, Differentially Regulates TLR7, and TLR9 Induced Responses., PMID:31312202
TLR9 agonist MGN1703 enhances B cell differentiation and function in lymph nodes., PMID:31300344
TLR9 signalling in HCV-associated atypical memory B cells triggers Th1 and rheumatoid factor autoantibody responses., PMID:31279905
Plasmacytoid dendritic cells protect against immune-mediated acute liver injury via IL-35., PMID:31264967
A proliferation-inducing ligand (APRIL) induced hyper-production of IgA from tonsillar mononuclear cells in patients with IgA nephropathy., PMID:31088610
Transitional B cells in quiescent SLE: An early checkpoint imprinted by IFN., PMID:31085070
Effects of 24-week Toll-like receptor 9 agonist treatment in HIV type 1+ individuals., PMID:30932955
Activation of T Lymphocytes as a Novel Mechanism in Beta1-Adrenergic Receptor Autoantibody-Induced Cardiac Remodeling-Additional Information About TLR9 Involvement., PMID:30880373
Repository corticotropin injection reverses critical elements of the TLR9/B cell receptor activation response in human B cells in vitro., PMID:30844442
Periodontal sources of citrullinated antigens and TLR agonists related to RA., PMID:30417696
In vivo cancer vaccination: Which dendritic cells to target and how?, PMID:30390423
TACI Isoforms Regulate Ligand Binding and Receptor Function., PMID:30333819
For research use only. Not for human or drug use.
