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Anti-MUC5B Antibody (R3W63)

Catalog #:   RHJ60301 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: ELISA, FCM, IHC
Accession: Q9HC84
Overview

Catalog No.

RHJ60301

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, IHC: 1:200-1:1000

Target

MUC5, High molecular weight salivary mucin MG1, Mucin-5 subtype B, tracheobronchial, Mucin-5B, MUC5B, MUC-5B, Sublingual gland mucin, Cervical mucin

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9HC84

Applications

ELISA, FCM, IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3W63

Data Image
  • Flow Cytometry
    Flow cytometric analysis of HL-60 cells using MUC5B mouse mAb (green) and negative control (red).
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human rectum tissues using MUC5B mouse mAb with DAB staining.
References

The Role of Pulmonary Genetic Variations in the Pathogenesis of Pediatric Postinfectious Bronchiolitis Obliterans., PMID:40196942

Detection of MUC1+/MUC2 and MUC5AC- Membrane-Associated Mucins in the Intraepithelial Surface Mucous Cells of the Developing Rabbit Esophagus., PMID:39396509

RSV infection of humanized lung-only mice induces pathological changes resembling severe bronchiolitis and bronchopneumonia., PMID:39175804

A novel immunofluorescence study of Lingual Salivary Glands in the Egyptian Tortoise (Testudo kleinmanni) and its ecological significance., PMID:39137537

High-throughput proteomic analysis of extracellular vesicles from saliva by chemical probe-based array., PMID:38772652

Down-Regulation of INSR Restores Th17/Treg Immune Balance and Alleviates Airway Hyperviscosity in Asthmatic Mice via Inactivation of STAT3 Pathway., PMID:38409842

Characterization of MdpS: an in-depth analysis of a MUC5B-degrading protease from Streptococcus oralis., PMID:38304711

Patient-level factors predictive of interstitial lung disease in rheumatoid arthritis: a systematic review., PMID:37507209

Genetic regulators of sputum mucin concentration and their associations with COPD phenotypes., PMID:37352370

Characterization of a highly conserved MUC5B-degrading protease, MdpL, from Limosilactobacillus fermentum., PMID:36925480

Exogenous Lipoxin A4 attenuates IL4-induced Mucin Expression in Human Airway Epithelial Cells., PMID:36860679

Identification and Characterization of MUC5B Binding Peptides by Phage Display., PMID:36701953

Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules., PMID:35776514

Novel Biomarkers, Diagnostic and Therapeutic Approach in Rheumatoid Arthritis Interstitial Lung Disease-A Narrative Review., PMID:35740390

Basiliximab Does Not Impair Airway Mucociliary Clearance of Rats., PMID:35715590

Anti-citrullinated protein antibody specificities and pulmonary fibrosis in relation to genetic loci in early rheumatoid arthritis., PMID:35532073

Study Effect of Azithromycin and Doxycycline in Mucus Producing and Inflammatory Signaling Pathways of Allergic Asthma., PMID:35490266

Bronchodilatory effect of higenamine as antiallergic asthma treatment., PMID:35410888

PlexinD1 Deficiency in Lung Interstitial Macrophages Exacerbates House Dust Mite-Induced Allergic Asthma., PMID:35110420

Mucins 5b and 7 and secretory IgA in the oral acquired pellicle of children with caries and caries-free children., PMID:34861462

Assessing predictors of rheumatoid arthritis-associated interstitial lung disease using quantitative lung densitometry., PMID:34747452

Lung macrophages drive mucus production and steroid-resistant inflammation in chronic bronchitis., PMID:34098956

Pregnancy-associated decrease of Siaα2-3Gal-linked glycans on salivary glycoproteins affects their binding ability to avian influenza virus., PMID:34097968

Pulmonary fibrosis in relation to genetic loci in an inception cohort of patients with early rheumatoid arthritis from northern Sweden., PMID:33993221

Association of TERT and DSP variants with microscopic polyangiitis and myeloperoxidase-ANCA positive vasculitis in a Japanese population: a genetic association study., PMID:33076992

Rheumatoid arthritis-associated interstitial lung disease: an overview of epidemiology, pathogenesis and management., PMID:32794076

The Association Between MUC5B Mutations and Clinical Outcome in Patients with Rheumatoid Arthritis-Associated Interstitial Lung Disease: A Retrospective Exploratory Study in China., PMID:32142504

Influence of MUC5B gene on antisynthetase syndrome., PMID:31996780

Involvement of PM2.5-bound protein and metals in PM2.5-induced allergic airway inflammation in mice., PMID:30849251

Association of MUC5B promoter polymorphism with interstitial lung disease in myeloperoxidase-antineutrophil cytoplasmic antibody-associated vasculitis., PMID:30765393

NOTCH3 contributes to rhinovirus-induced goblet cell hyperplasia in COPD airway epithelial cells., PMID:29991510

Characterization of mucoid and serous middle ear effusions from patients with chronic otitis media: implication of different biological mechanisms?, PMID:29915406

Early salivary changes in multiple myeloma patients undergoing autologous HSCT., PMID:29637662

A detection and quantification label-free tool to speed up downstream processing of model mucins., PMID:29315346

SLC3A2, antigen of mAb 3G9, promotes migration and invasion by upregulating of mucins in gastric cancer., PMID:29179459

Biofunctionalized Hybrid Magnetic Gold Nanoparticles as Catalysts for Photothermal Ablation of Colorectal Liver Metastases., PMID:28707960

Early Postnatal Secondhand Smoke Exposure Disrupts Bacterial Clearance and Abolishes Immune Responses in Muco-Obstructive Lung Disease., PMID:28667160

[Mucous cell differentiation and regulation of the gelling mucin Muc5b: a new tool for ex vivo and in vivo preclinical studies]., PMID:28612718

Innate immune defense in the inner ear - mucines are expressed by the human endolymphatic sac., PMID:28106268

Presence of DNA extracellular traps but not MUC5AC and MUC5B mucin in mucoid plugs/casts of infectious laryngotracheitis virus (ILTV) infected tracheas of chickens., PMID:27756631

Astragalus polysaccharide modulates ER stress response in an OVA-LPS induced murine model of severe asthma., PMID:27645929

MUC Expression in Gallbladder Epithelial Tissues in Cholesterol-Associated Gallbladder Disease., PMID:27563024

Detection and quantification of epithelial progenitor cell populations in human healthy and IPF lungs., PMID:27423691

Biosynthesis of the polymeric gel-forming mucin MUC5B., PMID:26993521

Meibomian Gland Absence Related Dry Eye in Ectodysplasin A Mutant Mice., PMID:26626448

Secretory IgA from submucosal glands does not compensate for its airway surface deficiency in chronic obstructive pulmonary disease., PMID:26432569

Interindividual variation, correlations, and sex-related differences in the salivary biochemistry of young healthy adults., PMID:25809904

Salivary mucins induce a Toll-like receptor 4-mediated pro-inflammatory response in human submandibular salivary cells: are mucins involved in Sjögren's syndrome?, PMID:25802401

SIgA binding to mucosal surfaces is mediated by mucin-mucin interactions., PMID:25793390

DNA methylation and childhood asthma in the inner city., PMID:25769910

Datasheet

Document Download

Anti-MUC5B Antibody (R3W63).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-MUC5B Antibody (R3W63) [RHJ60301]
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