Catalog No.
YHD67701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Gln68
Predicted molecular weight
33.77 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P25713
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Metallothionein-III, MT-III, MT-3, Growth inhibitory factor, GIFB, MT3, GIF, Metallothionein-3
Gender-Dependent Effect of Progesterone on the Expression of Metallothionein Genes in Rat Inguinal Adipose Tissue., PMID:40362306
Deciphering the molecular mechanisms of oil palm lipid metabolism through combined metabolomics and transcriptomics., PMID:40187314
Identification of a COMT Gene Involved in the Biosynthesis of Melatonin Which Mediates Resistance to Citrus Canker., PMID:40172092
Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor, FG4592, Induces Endogenous Metallothionein3 Expression in Human Neuronal Cell Line, ReNcell CX Cells., PMID:39993744
Metallothionein-1A (MT1A) Gene Variability May Play a Role in Female Frailty: A Preliminary Study., PMID:39858562
Upregulation of p52-ZER6 (ZNF398) increases reactive oxygen species by suppressing metallothionein-3 in neuronal cells., PMID:39809138
Characterization of VldE (Spr1875), a Pneumococcal Two-State l,d-Endopeptidase with a Four-Zinc Cluster in the Active Site., PMID:39722888
Oxidative pathways of apo, partially, and fully Zn(II)- and Cd(II)-metalated human metallothionein-3 are dominated by disulfide bond formation., PMID:39617990
Dietary Zinc Restriction and Chronic Restraint Stress Affect Mice Physiology, Immune Organ Morphology, and Liver Function., PMID:39599720
Proposed receptor-mediated mechanisms of melatonin in nitroglycerin-induced migraine-like hyperalgesic conditions in rats., PMID:39537039
m7G-modified mt-tRF3b-LeuTAA regulates mitophagy and metabolic reprogramming via SUMOylation of SIRT3 in chondrocytes., PMID:39454503
A Novel Manganese Ion Delivery Carrier Promotes Immune Cell Proliferation and Enhances Innate Immune Responses., PMID:39346829
Long Dynamic β1-β2 Loops in M. tb MazF Toxins Affect the Interaction Modes and Strengths of the Toxin-Antitoxin Pairs., PMID:39273577
Unique expression and critical role of metallothionein 3 in the control of osteoclastogenesis and osteoporosis., PMID:39085359
Melatonin induces proline, secondary metabolites, sugars and antioxidants activity to regulate oxidative stress and ROS scavenging in salt stressed sword lily., PMID:38961974
Metallothionein III Decreases the Proliferation of Astrocytes and Enhances Pathological Improvements in a Mouse Model of Alzheimer's Disease., PMID:38926108
Metallothionein 3 Potentiates Pulmonary Artery Smooth Muscle Cell Proliferation by Promoting Zinc-MTF1-ATG5 Axis-mediated Autophagosome Formation., PMID:38904023
Characterization of metallothionein genes from Broussonetia papyrifera: metal binding and heavy metal tolerance mechanisms., PMID:38840042
Biomarker Identification for Gender Specificity of Alzheimer's Disease Based on the Glial Transcriptome Profiles., PMID:38829108
Centenarian hippocampus displays high levels of astrocytic metallothioneins., PMID:38769809
Durlobactam, a Diazabicyclooctane β-Lactamase Inhibitor, Inhibits BlaC and Peptidoglycan Transpeptidases of Mycobacterium tuberculosis., PMID:38619138
Joint forces of mass spectrometric techniques (ICP-MS and MALDI-TOF-MS) and fluorescence spectrometry in the study of platinum-based cytostatic drugs interactions with metallothionein MT2 and MT3., PMID:38574532
Development of a pan-tau multivalent nanobody that binds tau aggregation motifs and recognizes pathological tau aggregates., PMID:38568030
ESI-MS analysis of Cu(I) binding to apo and Zn7 human metallothionein 1A, 2, and 3 identifies the formation of a similar series of metallated species with no individual isoform optimization for Cu(I)., PMID:38503570
Enhancement of Vitamin C's Protective Effect against Thimerosal-Induced Neurotoxicity in the Cerebral Cortex of Wistar Albino Rats: An In Vivo and Computational Study., PMID:38434836
Equilibrium, kinetic, and thermodynamic studies on the biosorption of lead by human metallothionein gene-cloned bacteria as a novel biosorbent., PMID:38385887
Prospective associations of technostress at work, burnout symptoms, hair cortisol, and chronic low-grade inflammation., PMID:38307447
Coexpression network analysis identified MT3 as a hub gene that promotes the chemoresistance of oral cancer by regulating the expression of YAP1., PMID:38041044
Metallothionein 3 promotes osteoclast differentiation and survival by regulating the intracellular Zn2+ concentration and NRF2 pathway., PMID:38040717
Integration of biophysical and biological approaches to validate fragment-like compounds targeting l,d-transpeptidases from Mycobacterium tuberculosis., PMID:37944368
Supermetalation of Cd-MT3 beyond the two-domain model., PMID:37832463
Metallothionein-3 and carbonic anhydrase metalation properties with Zn(II) and Cd(II) change as a result of protein-protein interactions., PMID:37723614
Analysis of a new therapeutic target and construction of a prognostic model for breast cancer based on ferroptosis genes., PMID:37643511
Procyanidin B2 alleviates uterine toxicity induced by cadmium exposure in rats: The effect of oxidative stress, inflammation, and gut microbiota., PMID:37515969
Structural Characterization of Cu(I)/Zn(II)-metallothionein-3 by Ion Mobility Mass Spectrometry and Top-Down Mass Spectrometry., PMID:37440218
Calcium-assisted sortase A cleavage of SUMOylated metallothionein constructs leads to high-yield production of human MT3., PMID:37434134
Metallothioneins, a Part of the Retinal Endogenous Protective System in Various Ocular Diseases., PMID:37371981
Biallelic mutations in RNA-binding protein ADAD2 cause spermiogenic failure and non-obstructive azoospermia in humans., PMID:37325547
Metallothionein-3: 63 Cu(I) binds to human 68 Zn7 -βα MT3 with no preference for Cu4 -β cluster formation., PMID:37165729
Role of TPEN in Amyloid-β25-35-Induced Neuronal Damage Correlating with Recovery of Intracellular Zn2+ and Intracellular Ca2+ Overloading., PMID:37059931
Preharvest melatonin foliar treatments enhance postharvest longevity of cut tuberose via altering physio-biochemical traits., PMID:37035084
Regulation of Aqueous Humor Secretion by Melatonin in Porcine Ciliary Epithelium., PMID:36982863
Effect of Mixing Time on Properties of Whole Wheat Flour-Based Cookie Doughs and Cookies., PMID:36900458
Metallothionein-3 attenuates the effect of Cu2+ ions on actin filaments., PMID:36801620
Anti-drug resistance, anti-inflammation, and anti-proliferation activities mediated by melatonin in doxorubicin-resistant hepatocellular carcinoma: in vitro investigations., PMID:36651944
Apo-metallothionein-3 cooperatively forms tightly compact structures under physiological conditions., PMID:36639030
Polymorphism analysis of the chloroplast and mitochondrial genomes in soybean., PMID:36611140
A novel built-in adjuvant metallothionein-3 aids protein antigens to induce rapid, robust, and durable immune responses., PMID:36426348
Melatonin Binding to Human NQO2 by Isothermal Titration Calorimetry., PMID:36180701
Cloning, Expression, Purification, Crystallization, and X-Ray Structural Determination of the Human NQO2 in Complex with Melatonin., PMID:36180700