Catalog No.
YHD66901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Val2613-Phe2746
Predicted molecular weight
17.25 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P25391
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Laminin subunit alpha-1, LAMA, S-LAM alpha, S-laminin subunit alpha, Laminin-3 subunit alpha, LAMA1, Laminin A chain, Laminin-1 subunit alpha, laminin 1, laminin 111, EHS laminin, laminin 3, laminin 121, S laminin
A Review of the Ocular Phenotype and Correlation with Genotype in Poretti-Boltshauser Syndrome., PMID:40428839
Aerobic exercise improves clearance of amyloid-β via the glymphatic system in a mouse model of Alzheimer's Disease., PMID:39971255
Astragalus polysaccharide attenuates retinal ischemia reperfusion-induced microglial activation through sortilin-related vacuolar protein sorting 10 domain containing receptor 2/laminin subunit alpha 1 upregulation., PMID:39958884
Gene Variant Spectrum in Probands With Familial Exudative Vitreoretinopathy Using an Expanded Panel., PMID:39918476
Downregulation of Genes for Skeletal Muscle Extracellular Matrix Components by Cisplatin., PMID:39522978
Germline DNA Damage Repair Gene Alterations in Patients with Metachronous Breast and Colorectal Cancer., PMID:39408606
Heterogeneous fibroblasts contribute to fibrotic scar formation after spinal cord injury in mice and monkeys., PMID:39060269
Analysis of serum peptidome profiles of non-metastatic and metastatic feline mammary carcinoma using liquid chromatography-tandem mass spectrometry., PMID:38951817
Lama1 upregulation prolongs the lifespan of the dyH/dyH mouse model of LAMA2-related congenital muscular dystrophy., PMID:38777118
Identification of established and novel extracellular matrix components in glioblastoma as targets for angiogenesis and prognosis., PMID:38775886
Case Report: An Adult Case of Poretti-Boltshauser Syndrome Diagnosed by Medical Checkup., PMID:38421477
European Joint Programme on Rare Diseases workshop: LAMA2-muscular dystrophy: paving the road to therapy March 17-19, 2023, Barcelona, Spain., PMID:38306718
Structural and Molecular Changes of Human Chondrocytes Exposed to the Rotating Wall Vessel Bioreactor., PMID:38254625
A proteomic analysis of atrial fibrillation in a prospective longitudinal cohort (AGES-Reykjavik study)., PMID:37967346
ITGB1 alleviates osteoarthritis by inhibiting cartilage inflammation and apoptosis via activating cAMP pathway., PMID:37941009
A Comprehensive Report of Intrinsically Disordered Regions in Inherited Retinal Diseases., PMID:37628652
lncRNA CLRN1-AS1 reduces adhesion ability of human trophoblasts via CXCL10/CXCL11., PMID:37531749
A perfusion-based three-dimensional cell culture system to model alveolar rhabdomyosarcoma pathological features., PMID:37296184
Bioinformatics analysis of key candidate genes and pathways in Chinese patients with keratoconus., PMID:37116607
Whole transcriptome sequencing reveals core genes related to spermatogenesis in Bactrian camels., PMID:37083698
18p Deletion Syndrome With Concurrent Frizzled-4 Mutation: Surgical Management of Bilateral Stage 5 Traction Retinal Detachment., PMID:37022334
CRISPRa-induced upregulation of human LAMA1 compensates for LAMA2-deficiency in Merosin-deficient congenital muscular dystrophy., PMID:36945402
Diverse logics and grammar encode notochord enhancers., PMID:36729834
A novel risk model based on the correlation between the expression of basement membrane genes and immune infiltration to predict the invasiveness of pituitary adenomas., PMID:36686480
Effects of experimental glaucoma in Lama1nmf223 mutant mice., PMID:36476399
Regulation of neural stem cell proliferation and survival by protein arginine methyltransferase 1., PMID:36440275
Laminin-111 mutant studies reveal a hierarchy within laminin-111 genes in their requirement for basal epithelial tissue folding., PMID:36244504
STAT3 in porcine endometrium during early pregnancy induces changes in extracellular matrix components and promotes angiogenesis†., PMID:35977090
Recessive LAMA5 Variants Associated With Partial Epilepsy and Spasms in Infancy., PMID:35663266
Temporal expression of Laminin-111 in the developing rat larynx., PMID:35483501
RTN4/Nogo-A-S1PR2 negatively regulates angiogenesis and secondary neural repair through enhancing vascular autophagy in the thalamus after cerebral cortical infarction., PMID:35263212
LAMA1 variants were identified Joubert syndrome patient., PMID:35224822
Stage-differentiated ensemble modeling of DNA methylation landscapes uncovers salient biomarkers and prognostic signatures in colorectal cancer progression., PMID:35202405
Therapeutic targeting of ARID1A and PI3K/AKT pathway alterations in cholangiocarcinoma., PMID:35070505
Epididymal embryonic development harbors TLR4/NFKB signaling pathway as a morphogenetic player., PMID:34915277
Antenatal presentation and supratentorial brain abnormalities in a child with Poretti-Boltshauser syndrome., PMID:34666927
Proteomic Response of Rat Pituitary Under Chronic Mild Stress Reveals Insights Into Vulnerability and Resistance to Anxiety or Depression., PMID:34603401
Comprehensive Analysis of the Expression and Prognosis for Laminin Genes in Ovarian Cancer., PMID:34512203
Quantitative Expression of TYR, CD34, and CALD1 Discriminates Between Canine Oral Malignant Melanomas and Soft Tissue Sarcomas., PMID:34422947
SLC39A5 dysfunction impairs extracellular matrix synthesis in high myopia pathogenesis., PMID:34302427
Circular RNA hsa_circ_0000277 sequesters miR-4766-5p to upregulate LAMA1 and promote esophageal carcinoma progression., PMID:34226522
Inhibition of macrophage migration inhibitory factor (MIF) as a therapeutic target in bleomycin-induced pulmonary fibrosis rats., PMID:33881353
Multiscale molecular profiling of pathological bone resolves sexually dimorphic control of extracellular matrix composition., PMID:33563616
Pancreatic progenitor epigenome maps prioritize type 2 diabetes risk genes with roles in development., PMID:33544077
Abnormal promoter DNA hypermethylation of the integrin, nidogen, and dystroglycan genes in breast cancer., PMID:33500458
Multivariate genome wide association and network analysis of subcortical imaging phenotypes in Alzheimer's disease., PMID:33372590
Whole exome sequencing identifies the novel putative gene variants related with type 2 diabetes in Mizo population, northeast India., PMID:33059026
Differential Gene Expression between Limbal Niche Progenitors and Bone Marrow Derived Mesenchymal Stem Cells., PMID:32174786
Omics data-driven analysis identifies laminin-integrin-mediated signaling pathway as a determinant for cell differentiation in oral squamous cell carcinoma., PMID:31611435
For research use only. Not for human or drug use.
