Catalog No.
YHD66401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ile30-Lys248
Predicted molecular weight
27.07 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P25189
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
MPZ, Myelin protein zero, Myelin protein P0, Myelin peripheral protein, MPP
PATJ regulates cell stress responses and vascular remodeling post-stroke., PMID:40472775
Gene expression profiling of extraocular muscles in primary inferior oblique overaction., PMID:40452936
Transcription Factors and Coregulators in Schwann Cell Differentiation, Myelination, and Remyelination: Implications for Peripheral Neuropathy., PMID:40452391
Identification of Differentially Expressed Genes in Spinal Cord Injury., PMID:40428335
Transcriptome analysis reveals the immune responses of leopard coral grouper to nervous necrosis virus infection., PMID:40118231
A dose escalation and safety study of AAVrh10-mediated Schwann cell-targeted gene therapy for CMT1X., PMID:40055046
Hereditary, non HINT1 related, axonal neuropathy with neuromyotonia., PMID:40009145
Generation of two induced pluripotent stem cell lines from Charcot-Marie-Tooth type 1B patients harboring autosomal dominant mutations in myelin protein zero gene., PMID:39986019
Activation of XBP1s attenuates disease severity in models of proteotoxic Charcot-Marie-Tooth type 1B., PMID:39979221
Genetic landscape of Charcot-Marie-Tooth disease in Vietnam: A prospective multicenter study., PMID:39973457
Mepolizumab efficacy and safety in patients with eosinophilic granulomatosis with polyangiitis in real practice: Data from a Spanish retrospective multicentric register from Rheumatology departments., PMID:39894626
Phosphodiesterase 4D inhibition improves the functional and molecular outcome in a mouse and human model of Charcot Marie Tooth disease 1 A., PMID:39823724
Edaravone Improves Motor Dysfunction Following Brachial Plexus Avulsion Injury in Rats., PMID:39791183
Delineating the genetic landscape of Charcot-Marie-tooth disease in Türkiye: Distinct distribution, rare phenotypes, and novel variants., PMID:39776111
Disrupting the transmembrane domain interface between PMP22 and MPZ causes peripheral neuropathy., PMID:39759075
Genetically confirmed Charcot-Marie-Tooth disease type 2A manifesting with postural tremor: a case report., PMID:39604983
Transcriptome analysis revealed the mechanism of skeletal muscle growth and development in different hybrid sheep., PMID:39483021
Long-term efficacy of mepolizumab in patients with eosinophilic granulomatosis with polyangiitis: a propensity score matching analysis in the multicenter REVEAL cohort study., PMID:39416779
Navigating the Landscape of CMT1B: Understanding Genetic Pathways, Disease Models, and Potential Therapeutic Approaches., PMID:39273178
Three cases of relapsed eosinophilic sinusitis without eosinophilia during mepolizumab maintenance therapy for eosinophilic granulomatosis with polyangiitis., PMID:39249645
Tumor microenvironment (Part I): Tissue integrity in a rat model of peripheral neural cancer., PMID:39050471
Study on Cytochrome P450 Metabolic Profile of Paclitaxel on Rats using QTOF-MS., PMID:39039675
Biological characteristics of tissue engineered-nerve grafts enhancing peripheral nerve regeneration., PMID:39020413
Identification of cellular and noncellular components of mature intact human peripheral nerve., PMID:38973168
EGR3 Inhibits Tumor Progression by Inducing Schwann Cell-Like Differentiation., PMID:38973154
The cytoplasmic tail of myelin protein zero induces morphological changes in lipid membranes., PMID:38971517
Characterization of sciatic nerve myelin sheath during development in C57BL/6 mice., PMID:38951719
Prevention of Chronic Diabetic Neuropathy and Diabetes-Associated Cognitive Impairment Using Medicinal Herbs (Cassia Angustifolia and Nigella Sativa)., PMID:38947105
Phenotypic spectrum of myelin protein zero-related neuropathies: a large cohort study from five mutation clusters across Italy., PMID:38839277
Veno-Occlusive Disease: A Life-saving Novel Approach With Plasma Exchange, IVIG, and Steroid, Without Defibrotide., PMID:38810004
Factors associated with drug retention of mepolizumab in patients with eosinophilic granulomatosis with polyangiitis: A multicentre REVEAL cohort study., PMID:38727536
Influence of Magnesium Degradation on Schwannoma Cell Responses to Nerve Injury Using an In Vitro Injury Model., PMID:38667545
Schwann cell-derived extracellular vesicles promote memory impairment associated with chronic neuropathic pain., PMID:38632655
Bone marrow stromal cell-conditioned medium regenerates injured sciatic nerve by increasing expression of MPZ and NGF and decreasing apoptosis., PMID:38629102
Effects of Idebenone on Rat Schwann Cells with Toxicity Induced by Hydrogen Peroxide: Assessment of Molecular, Apoptosis, and Oxidative Stress Parameters., PMID:38628092
Deciphering the molecular landscape: integrating single-cell transcriptomics to unravel myofibroblast dynamics and therapeutic targets in clear cell renal cell carcinomas., PMID:38562930
Case report: A novel variant (H49N) in Myelin Protein Zero gene is responsible for a patient with Charcot-Marie-Tooth disease., PMID:38481944
Material matters: Degradation products affect regenerating Schwann cells., PMID:38479242
Activation of XBP1s attenuates disease severity in models of proteotoxic Charcot-Marie-Tooth type 1B., PMID:38352425
Charcot-Marie-Tooth Disease with Myelin Protein Zero Mutation Presenting as Painful, Predominant Small-Fiber Neuropathy., PMID:38338934
CRISPR activation to characterize splice-altering variants in easily accessible cells., PMID:38272032
Disrupting the transmembrane domain interface between PMP22 and MPZ causes peripheral neuropathy., PMID:38187781
Proteomic Identification of Seasonally Expressed Proteins Contributing to Heart Function and the Avoidance of Skeletal Muscle Disuse Atrophy in a Hibernating Mammal., PMID:38117800
Clinical Worsening of Charcot-Marie-Tooth Disease Due to Overlapping Acute Inflammatory Polyneuropathy., PMID:38021856
Transcriptomic alterations in the olfactory bulb induced by exposure to air pollution: Identification of potential biomarkers and insights into olfactory system function., PMID:37981204
Hemokinin-1 induces transcriptomic alterations in pain-related signaling processes in rat primary sensory neurons independent of NK1 tachykinin receptor activation., PMID:37965042
Proteomic analysis of peripheral nerve myelin during murine aging., PMID:37964793
Platinum-based chemotherapy induces demyelination of Schwann cells in oral squamous cell carcinoma treatment., PMID:37944569
Bioinformatics Analysis Reveals Novel Differentially Expressed Genes Between Ectopic and Eutopic Endometrium in Women with Endometriosis., PMID:37916013
For research use only. Not for human or drug use.
