Catalog No.
YHD65901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp21-Lys80
Predicted molecular weight
19.32 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P25101
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Endothelin-1 receptor, ETA, ET-A, ETRA, Endothelin receptor type A, EDNRA, hET-AR, ETA-R
Transcriptome and proteome profile analysis of the regulation of chicken ovarian development., PMID:40466268
Myocyte-Specific Enhancer Factor 2A Potentiates Osteoclastic Differentiation in Osteoporosis by Inducing Endothelin Receptor Type A., PMID:40369222
Crosstalk Between Gastric Cancer and Adjacent Mucosa Reveals EDN1-EDNRA-Mediated Regulation of Cancer Stemness and Immunomodulation Networks., PMID:40245183
The Gq/11 family of Gα subunits is necessary and sufficient for lower jaw development., PMID:40171762
Epigenetic alteration of smooth muscle cells regulates endothelin-dependent blood pressure and hypertensive arterial remodeling., PMID:40146226
Large-scale multi-omics identifies drug targets for heart failure with reduced and preserved ejection fraction., PMID:39915329
Association of endothelial nitric oxide synthase (NOS3) rs2070744 variant with advanced retinopathy of prematurity: a case-control study and meta-analysis., PMID:39747280
Twist1 Acts Upstream of the Dlx5-Hand2 Pathway to Pattern the Mammalian Jaw., PMID:39707586
EDNRA regulates the tumour immune environment and predicts the efficacy and prognosis of cancer immunotherapy., PMID:39601333
Right Ventricular Hypertrophy in Spontaneously Hypertensive Rats (SHR/NHsd) Is Associated with Inter-Individual Variations of the Pulmonary Endothelin System., PMID:39452062
EDNRA affects susceptibility to large artery atherosclerosis stroke through potential inflammatory pathway., PMID:39448657
The Gq/11 family of Gα subunits is necessary and sufficient for lower jaw development., PMID:39345358
Gastric cancer fibroblasts affect the effect of immunotherapy and patient prognosis by inducing micro-vascular production., PMID:39040110
Investigation of single nucleotide polymorphisms in differentially expressed genes and proteins reveals the genetic basis of skeletal muscle growth differences between Tibetan and Large White pigs., PMID:38938033
Microarray analysis demonstrates up-regulation of the endothelin-1 gene with compensatory down-regulation of the ETA receptor gene in human portal vein., PMID:38860875
Utilizing genetics and proteomics to assess the role of antihypertensive drugs in human longevity and the underlying pathways: a Mendelian randomization study., PMID:38769606
Investigating gene signatures associated with immunity in colon adenocarcinoma to predict the immunotherapy effectiveness using NFM and WGCNA algorithms., PMID:38742936
Enhanced quality of hESC-derived melanocytes through modified concentration of endothelin-1., PMID:38284190
Identification of EDNRA as the Key Biomarker for Hypercholesterolemia and Colorectal Cancer., PMID:38123303
[Study of the clinical significance of ETAR mRNA expression in high-grade serous ovarian cancer and the inhibitory effect of ETAR derived fusion polypeptide on cancer progression]., PMID:38123199
Assessment of the anti-inflammatory mechanism of quercetin 3,7-dirhamnoside using an integrated pharmacology strategy., PMID:37806949
A homozygous missense variant in the PLCB4 gene causes severe phenotype of auriculocondylar syndrome type 2., PMID:37596802
Identification and validation of shared genes and key pathways in endometriosis and endometriosis-associated ovarian cancer by weighted gene co-expression network analysis and machine learning algorithms., PMID:37340502
Endothelin Receptor Antagonists in Kidney Disease., PMID:36834836
Targeting Immune-Fibroblast Crosstalk in Myocardial Infarction and Cardiac Fibrosis., PMID:36747878
The interaction of β-arrestin1 with talin1 driven by endothelin A receptor as a feature of α5β1 integrin activation in high-grade serous ovarian cancer., PMID:36717550
Mandibulofacial dysostosis with alopecia results from ETAR gain-of-function mutations via allosteric effects on ligand binding., PMID:36637912
Tracing G-Protein-Mediated Contraction and Relaxation in Vascular Smooth Muscle Cell Spheroids., PMID:36611924
Endothelin-3 is epigenetically silenced in endometrioid endometrial cancer., PMID:36542159
Hydroxytyrosol decreases EDNRA expression through epigenetic modification in colorectal cancer cells., PMID:36528246
Whole-genome identification of transposable elements reveals the equine repetitive element insertion polymorphism in Chinese horses., PMID:36464985
The EDN1/EDNRA/β‑arrestin axis promotes colorectal cancer progression by regulating STAT3 phosphorylation., PMID:36453252
Identification of a dysregulated CircRNA-associated gene signature for predicting prognosis, immune landscape, and drug candidates in bladder cancer., PMID:36300085
Network Pharmacology and Molecular Docking-Based Mechanism Study to Reveal Antihypertensive Effect of Gedan Jiangya Decoction., PMID:36046450
MicroRNA-342-3p loaded by human umbilical cord mesenchymal stem cells-derived exosomes attenuates deep vein thrombosis by downregulating EDNRA., PMID:36006542
Effects of Cyclosporine A and Adalimumab on the expression profiles histaminergic system-associated genes and microRNAs regulating these genes in HaCaT cells., PMID:35899934
Multinational Genome-Wide Association Study and Functional Genomics Analysis Implicates Decreased SIRT3 Expression Underlying Intracranial Aneurysm Risk., PMID:35838494
Endothelin system expression in the kidney following cisplatin-induced acute kidney injury in male and female mice., PMID:35704945
Jian Pi Tiao Gan Yin alleviates obesity phenotypes through mTORC1/SREBP1 signaling in vitro and in vivo., PMID:35433951
Whole-Transcriptome Analysis of Serum L1CAM-Captured Extracellular Vesicles Reveals Neural and Glycosylation Changes in Autism Spectrum Disorder., PMID:35412111
Auriculocondylar syndrome 2 results from the dominant-negative action of PLCB4 variants., PMID:35284927
Andrographolide Promotes Interaction Between Endothelin-Dependent EDNRA/EDNRB and Myocardin-SRF to Regulate Pathological Vascular Remodeling., PMID:35127859
Association of polymorphisms in endothelin-1 and endothelin receptor a genes with vasovagal syncope., PMID:35043642
Functionally Active Antibodies to the Angiotensin II Type 1-Receptor Measured by a Luminometric Bioassay Do Not Correlate With Clinical Manifestations in Systemic Sclerosis: A Comparison With Antibodies to Vascular Receptors and Topoisomerase I Detected by ELISA., PMID:34956217
Twenty-Five Novel Loci for Carotid Intima-Media Thickness: A Genome-Wide Association Study in >45 000 Individuals and Meta-Analysis of >100 000 Individuals., PMID:34852643
Anthracycline-induced cardiotoxicity in women without cardiovascular diseases: molecular and genetic predictors., PMID:34783301
Effects and prognostic values of miR-30c-5p target genes in gastric cancer via a comprehensive analysis using bioinformatics., PMID:34663825
[Mechanism of Astragali Radix-Coptis Rhizoma pair in treating type 2 diabetes mellitus based on network pharmacology]., PMID:34581092
Endosomal disentanglement of a transducible artificial transcription factor targeting endothelin receptor A., PMID:34547467
Multi-disciplinary management of patients with benign airway strictures: A review., PMID:34481304
For research use only. Not for human or drug use.
