Catalog No.
YHD63501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly31-Gly240
Predicted molecular weight
24.56 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P24592
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Insulin-like growth factor-binding protein 6, IBP-6, IBP6, IGFBP-6, IGF-binding protein 6, IGFBP6
The role of IGF-2 and its variants in enhancing endothelial migration and angiogenesis., PMID:40454313
Enhancing Prognostic Signatures in Glioblastoma with Feature Selection and Regularised Cox Regression., PMID:40428295
Distinct Urinary Proteome Changes Across Estimated Glomerular Filtration Rate Stages in a Cohort of Black South Africans., PMID:40004202
A Risk Model Based on Ferroptosis-Related Genes OSMR, G0S2, IGFBP6, IGHG2, and FMOD Predicts Prognosis in Glioblastoma Multiforme., PMID:39815665
Endothelial IGFBP6 suppresses vascular inflammation and atherosclerosis., PMID:39794479
Swimming induces physiological cardioprotection associated with pro-growth versus anti-inflammatory influences in extracardiac organs., PMID:39792091
Insulin-like growth factor binding protein-6 modulates proliferative antagonism in response to progesterone in breast cancer., PMID:39698031
CXCL12 restricts tumor growth by suppressing the Ras, ERK1/2, c-Myc, and the immune checkpoint PD-L1 pathways., PMID:39689179
Unraveling molecular signatures and prognostic biomarkers in glioblastoma: a comprehensive study on treatment resistance and personalized strategies., PMID:39630160
IGFBP6 Modulates Proteostasis by Activating ATF4 Targets and Reducing ER Retrotranslocon Expression., PMID:39480639
Single-cell sequencing analysis and bulk-seq identify IGFBP6 and TNFAIP6 as novel differential diagnosis markers for postburn pathological scarring., PMID:39317554
Deep and unbiased proteomics, pathway enrichment analysis, and protein-protein interaction of biomarker signatures in migraine., PMID:39314676
Prognostic Value of IGFBP6 in Breast Cancer: Focus on Glucometabolism., PMID:39275851
Combination of transcriptomics and proteomics for analyzing potential biomarker and molecular mechanism underlying skeletal muscle atrophy., PMID:39179024
AP collagen peptides (APCPs) promote hair growth by activating the GSK-3β/β-catenin pathway and improve hair condition., PMID:39031460
IGFBP6 regulates extracellular vesicles formation via cholesterol abundance in MDA-MB-231 cells., PMID:38942135
A novel role of IGFBP5 in the migration, invasion and spheroids formation induced by IGF-I and insulin in MCF-7 breast cancer cells., PMID:38896333
[Experimental study of APB-DOCK8 transgenic tomato vaccine for caries prevention]., PMID:38494961
Changes in the Expression of Proteins Associated with Neurodegeneration in the Brains of Mice after Infection with Influenza A Virus with Wild Type and Truncated NS1., PMID:38473707
Prior Exposure to Experimental Preeclampsia Increases Atherosclerotic Plaque Inflammation in Atherogenic Mice-Brief Report., PMID:38450510
Complement system dysregulation in synovial fluid from patients with persistent inflammation following anterior cruciate ligament reconstruction surgery., PMID:38343688
Scaling up polarized RPE cell supernatant production on parylene membrane., PMID:38242423
Integrating single-cell and bulk transcriptomic analyses to develop a cancer-associated fibroblast-derived biomarker for predicting prognosis and therapeutic response in breast cancer., PMID:38235137
Behavioral and transcriptional effects of repeated electroconvulsive seizures in the neonatal MK-801-treated rat model of schizophrenia., PMID:38081977
POLE2 Regulates Apoptosis of Oral Squamous Cell Carcinoma Cells through the PI3K/AKT Signaling Pathway., PMID:38079056
Lysine lactylation (Kla) might be a novel therapeutic target for breast cancer., PMID:37950222
Expressions of Insulin-like Growth Factor System among Different Breeds Impact Piglets' Growth during Weaning., PMID:37835617
Multiplex analysis of inflammatory proteins associated with risk of coronary artery disease in type-1 diabetes patients., PMID:37822049
Single-cell transcriptomic analysis reveals crucial oncogenic signatures and its associative cell types involved in gastric cancer., PMID:37740827
Silencing POLE2 promotes apoptosis and inhibits proliferation of oral squamous cell carcinomas by inhibiting PI3K/AKT signaling pathway., PMID:37733085
Identification and analysis of cellular senescence-associated signatures in diabetic kidney disease by integrated bioinformatics analysis and machine learning., PMID:37396184
Effect of IGFBP6 Knockdown on Proteins Regulating Exosome Synthesis and Secretion in MDA-MB-231 Cell Line., PMID:37336811
Expression characteristics and their functional role of IGFBP gene family in pan-cancer., PMID:37088808
Tectorigenin alleviates the apoptosis and inflammation in spinal cord injury cell model through inhibiting insulin-like growth factor-binding protein 6., PMID:37069938
Evaluation of SNPs from human IGFBP6 associated with gene expression: an in-silico study., PMID:36946206
Comparison of the Cost and Effect of Combined Conditioned Medium and Conventional Medium for Fallopian Tube Organoid Cultures., PMID:36919683
IGFBP-6 Network in Chronic Inflammatory Airway Diseases and Lung Tumor Progression., PMID:36902237
IGFBP-6 Alters Mesenchymal Stromal Cell Phenotype Driving Dasatinib Resistance in Chronic Myeloid Leukemia., PMID:36836615
Circulating Adipokines and Hepatokines Serve as Diagnostic Markers during Obesity Therapy., PMID:36430499
GALNT14-mediated O-glycosylation on PHB2 serine-161 enhances cell growth, migration and drug resistance by activating IGF1R cascade in hepatoma cells., PMID:36376274
Association of serum biomarkers with early neurologic improvement after intravenous thrombolysis in ischemic stroke., PMID:36315566
Plasma human growth cytokines in children with vasovagal syncope., PMID:36312268
Identification of immune cell infiltration and diagnostic biomarkers in unstable atherosclerotic plaques by integrated bioinformatics analysis and machine learning., PMID:36211422
Potential novel biomarkers in small intestine for obesity/obesity resistance revealed by multi-omics analysis., PMID:36209126
Nomogram Models Based on the Gene Expression in Prediction of Breast Cancer Bone Metastasis., PMID:36046013
IGF-binding proteins secreted by cancer-associated fibroblasts induce context-dependent drug sensitization of lung cancer cells., PMID:35973030
Crosstalk between Growth and Osmoregulation of GHRH-SST-GH-IGF Axis in Triploid Rainbow Trout (Oncorhynchus mykiss)., PMID:35955823
Comparative Genomic Characterization of Insulin-Like Growth Factor Binding Proteins in Cattle and Buffalo., PMID:35924270
Insulin-Like Growth Factor Binding Protein (IGFBP-6) as a Novel Regulator of Inflammatory Response in Cystic Fibrosis Airway Cells., PMID:35903151
Comprehensive Analysis of Prognostic Value and Immune Infiltration of IGFBP Family Members in Glioblastoma., PMID:35832140
For research use only. Not for human or drug use.
