Catalog No.
YHD60401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro175-Gly480
Predicted molecular weight
34.81 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P23769
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
GATA2, GATA-binding protein 2, Endothelial transcription factor GATA-2
Bioinformatics analysis of hub genes and oxidative stress-related pathways in odontogenic keratocysts., PMID:40505773
Genome-wide CRISPR screens identify PTGES3 as a novel AR modulator., PMID:40501535
GATA Transcription Factors: A Cross-Road for Erythropoiesis, Neurodevelopment, and Synucleinopathies., PMID:40474753
IFITM1 promotes proliferation, migration and macrophage-like transdifferentiation of vascular smooth muscle cells via c-Src/MAPK/GATA2/E2F2 pathway in atherosclerosis., PMID:40466954
Dual mechanism of inflammation sensing by the hematopoietic progenitor genome., PMID:40435239
A pluripotent stem cell model of Emberger syndrome reveals reduced lymphatic endothelial differentiation., PMID:40434572
Uncovering dendritic cell specific biomarkers for diagnosis and prognosis of cardiomyopathy using single cell RNA sequencing and comprehensive bioinformatics analysis., PMID:40419517
The progression of multiple myeloma is regulated by LILRB1 via the GATA2-SAGE1 pathway., PMID:40415416
Glioneuronal tumors PATZ1-fused: clinico-molecular and DNA methylation signatures for a variety of morphological and radiological profiles., PMID:40413488
The molecular basis of music-induced neuroplasticity in humans: A systematic review., PMID:40412457
The SAMD1 transcription factor coordinates hematopoietic lineage differentiation and H3K4 methylation status., PMID:40402130
Identification of cell specific biomarkers for intellectual disability via single cell RNA sequencing and transcriptomic bioinformatics approaches., PMID:40399537
A searchable atlas of pathogen-sensitive lncRNA networks in human macrophages., PMID:40399309
CT features of genetic mutation-related pulmonary alveolar proteinosis (CCR2 and GATA2 deficiency., PMID:40340131
Peripheral blood GATA2 expression impacts RNF213 mutation penetrance and clinical severity in moyamoya disease., PMID:40268337
m6A-Modified GATA2 Enhances Odontogenic Differentiation in Stem Cells from the Apical Papilla., PMID:40243520
Gene Mutation Characteristics and Prognostic Significance in Acute Myeloid Leukemia Patients From Northeast China., PMID:40226311
Drug survival of omalizumab in atopic asthma: Impact of clinical and genetic variables., PMID:40189906
Exploring bioactive natural products for treating neurodegenerative diseases: a computational network medicine approach targeting the estrogen signaling pathway in amyotrophic lateral sclerosis and Parkinson's disease., PMID:40184012
GATA2 promotes cervical cancer progression under the transcriptional activation of TRIP4., PMID:40180167
PU.1/Spi1 exacerbates ischemia-reperfusion induced acute kidney injury via upregulating Gata2 and promoting fibroblast activation., PMID:40169783
Loss of GATA2 promotes invasion and predicts cancer recurrence and survival in uterine serous carcinoma., PMID:40168074
DOCK2 Deficiency and GATA2 Haploinsufficiency Can Underlie Critical Coronavirus Disease 2019 (COVID-19) Pneumonia., PMID:40153067
Construction and evaluation of a diagnostic model for Alzheimer's disease based on mitophagy-related genes., PMID:40148430
Hematological phenotypes in GATA2 deficiency syndrome arise from aging, maladaptation to proliferation, and somatic events., PMID:40138552
Exploring common genomic biomarkers to disclose common drugs for the treatment of colorectal cancer and hepatocellular carcinoma with type-2 diabetes through transcriptomics analysis., PMID:40127075
FOXL2 drives the differentiation of supporting gonadal cells in early ovarian development., PMID:40102860
Single-nucleus multiomics reveals the gene regulatory networks underlying sex determination of murine primordial germ cells., PMID:40063068
An Attention-Aware Multi-Task Learning Framework Identifies Candidate Targets for Drug Repurposing in Sarcopenia., PMID:40045692
CTCF is selectively required for maintaining chromatin accessibility and gene expression in human erythropoiesis., PMID:40022213
[Relationships between Molecular Genetics and Clinical Features of Children with Acute Myeloid Leukemia]., PMID:40017188
IL-6/GATA2/SERPINE1 pathway is implicated in regulating cellular senescence after acute kidney injury., PMID:40007559
Aggressive Head and Neck Squamous Cell Carcinoma in the Setting of GATA2 Deficiency., PMID:39981594
Bone Marrow CD8 + Abundance Inversely Correlates with Progressive Marrow Fibrosis and Myelodysplastic Evolution in GATA2 Deficiency: Case Report., PMID:39976744
Sequence-structure based prediction of pathogenicity for amino acid substitutions in proteins associated with primary immunodeficiencies., PMID:39975544
CRISPR screening identifies regulators of enhancer-mediated androgen receptor transcription in advanced prostate cancer., PMID:39954255
Comprehensive exploration of programmed cell death landscape in lung adenocarcinoma combining multi-omic analysis and experimental verification., PMID:39948103
Systematic identification and validation of ceRNA-driven regulatory mechanisms in pediatric β-Thalassemia major., PMID:39930261
Integrative bioinformatic approach reveals novel melatonin-related biomarkers for Alzheimer's disease., PMID:39905093
GATA2 mutated allele specific expression is associated with a hyporesponsive state of HSC in GATA2 deficiency syndrome., PMID:39885120
GATA2 links stemness to chemotherapy resistance in acute myeloid leukemia., PMID:39841459
Modeling GATA2 deficiency in mice: the R396Q mutation disrupts normal hematopoiesis., PMID:39774796
GATA2 participates in protection against hypoxia-induced pulmonary vascular remodeling., PMID:39739870
Microcystin-LR Exposure Damages Neurons by Inducing α-Syn Aggregation via MAPK4/GATA2/SNCA and PP2A/GRKs Pathways., PMID:39738876
IRX-related homeobox gene MKX is a novel oncogene in acute myeloid leukemia., PMID:39689089
Deciphering the Role of the SREBF1 Gene in the Transcriptional Regulation of Porcine Adipogenesis Using CRISPR/Cas9 Editing., PMID:39684387
Transcriptional regulation of basophil-specific protease genes by C/EBPα, GATA2, TGF-β signaling, and epigenetic mechanisms., PMID:39660487
KIF20A activated by transcription factor GATA2 promotes cell growth in hepatitis B virus-related hepatocellular carcinoma., PMID:39624268
Rare Case of Germline GATA2-Deficiency With Merkel Cell Carcinoma and Acute Myeloid Leukemia., PMID:39614632
Sox17 and Other SoxF-Family Proteins Play Key Roles in the Hematopoiesis of Mouse Embryos., PMID:39594589
For research use only. Not for human or drug use.
