Catalog No.
YHD56901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly220-Ala426
Predicted molecular weight
25.40 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P23368
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ME2, NAD-dependent malic enzyme, mitochondrial, Malic enzyme 2, NAD-ME
Transcriptome Analysis Reveals Co-Expression Regulation of Sugar Transport and Signaling Networks in Initiating Stolon-to-Tuber Transition in Potato., PMID:40508086
Protein interaction network drive more group integrated analytic larynx hub protein markers: LYVE1/FBLN5/INMT/DCN/ZFY/RSPO3 protein macromolecule collaborative diagnosis of a new era., PMID:40419046
2-Methoxyestradiol attenuates lung injury induced by chronic intermittent hypoxia via inhibiting the HIF1-α/SLC7A11 pathway., PMID:40399397
LSD1 induces H3 K9 demethylation to promote adipogenesis in thyroid-associated ophthalmopathy., PMID:40340927
[Protein C activator derived from snake venom protects human umbilical vein endothelial cells against hypoxia-reoxygenation injury by suppressing ROS via upregulating HIF-1α and BNIP3]., PMID:40159976
Comprehensive molecular characteristics of hepatocellular carcinoma based on multi-omics analysis., PMID:40159482
ACAT1-Mediated ME2 Acetylation Drives Chemoresistance in Ovarian Cancer by Linking Glutaminolysis to Lactate Production., PMID:39951294
The difference between young and older ducks: Amino acid, free fatty acid, nucleotide compositions and breast muscle proteome., PMID:39810946
A mutant ASXL1-EHMT complex contributes to heterochromatin dysfunction in clonal hematopoiesis and chronic monomyelocytic leukemia., PMID:39803572
Characterization of mint virus C, a new member of the genus Carlavirus., PMID:39792272
A mutant ASXL1-BAP1-EHMT complex contributes to heterochromatin dysfunction in clonal hematopoiesis and chronic monomyelocytic leukemia., PMID:39752521
Facile preparation of sulfonium peptide and protein probes for selective crosslinking of methyllysine readers., PMID:39720136
ANGPTL4 mediated mesothelial-mesenchymal transition in pulmonary fibrosis: a potential therapeutic target., PMID:39707362
Selective photo crosslinking to methylarginine readers by sulfonium peptides., PMID:39642578
A Targeted Octahedral DNA Nanostructure Co-delivers siME3 and Doxorubicin to Enhance Collateral Lethality in ME2-Deficient Pancreatic Cancer., PMID:39602246
PRMT1-mediated methylation of ME2 promotes hepatocellular carcinoma growth by inhibiting ubiquitination., PMID:39528487
Novel pharmacologic inhibition of lysine-specific demethylase 1 as a potential therapeutic for glioblastoma., PMID:39501082
Metabolic dysfunction-associated steatotic liver disease-associated fibrosis and cardiac dysfunction in patients with type 2 diabetes., PMID:39492975
Evaluation of Retinal Structure and Visual Function in Blue Cone Monochromacy to Develop Clinical Endpoints for L-opsin Gene Therapy., PMID:39408969
ME2 Deficiency Is Associated With Recessive Neurodevelopmental Disorder., PMID:39401966
Regulatory network of the late-recruited primary decarboxylase C4NADP-ME in sugarcane., PMID:39276364
Malic enzyme 2 maintains metabolic state and anti-tumor immunity of CD8+ T cells., PMID:39151423
Combining RNAscope, Immunohistochemistry (IHC) and Digital Image Analysis to Assess Podoplanin (PDPN) Protein and PDPN_mRNA Expression on Formalin-Fixed Paraffin-Embedded Normal Human Placenta Tissues., PMID:38920982
Histone demethylase KDM4A mediating macrophage polarization: A potential mechanism of trichloroethylene induced liver injury., PMID:38800986
The Unique Role of the Second Coordination Sphere to Unlock and Control Catalysis in Nonheme Fe(II)/2-Oxoglutarate Histone Demethylase KDM2A., PMID:38781256
Validation of Human Bone Marrow-derived Mesenchymal Stem Cells and MCF-7 Breast Cancer Cells Co-culture Using a 3D Perfused Biomimetic Microfluidic Platform., PMID:38537998
Two DOT1 enzymes cooperatively mediate efficient ubiquitin-independent histone H3 lysine 76 tri-methylation in kinetoplastids., PMID:38503750
Epigenetic insights into Familial Mediterranean Fever: Increased RGS10 expression and histone modifications accompanies inflammation in familial Mediterranean fever disease., PMID:38331118
AKT1 phosphorylation of cytoplasmic ME2 induces a metabolic switch to glycolysis for tumorigenesis., PMID:38263319
The Interplay Between HIF-1α and EZH2 in Lung Cancer and Dual-Targeted Drug Therapy., PMID:38072662
M2 macrophage-derived exosomes induce angiogenesis and increase skin flap survival through HIF1AN/HIF-1α/VEGFA control., PMID:38030054
SIRT5-mediated ME2 desuccinylation promotes cancer growth by enhancing mitochondrial respiration., PMID:38007551
Identification of key biomarkers in RF-negative polyarticular and oligoarticular juvenile idiopathic arthritis by bioinformatic analysis., PMID:38001449
DOT1L interaction partner AF10 controls patterning of H3K79 methylation and RNA polymerase II to maintain cell identity., PMID:37995701
Slc11 Synapomorphy: A Conserved 3D Framework Articulating Carrier Conformation Switch., PMID:37894758
Nitrite and Nitric Oxide Interconversion at Mononuclear Copper(II): Insight into the Role of the Red Copper Site in Denitrification., PMID:37800603
Depletion of G9A attenuates imiquimod-induced psoriatic dermatitis via targeting EDAR-NF-κB signaling in keratinocyte., PMID:37739945
Intermittent hypoxia induces myofibroblast differentiation and extracellular matrix production of MRC5s via HIF-1α-TGF-β/Smad pathway., PMID:37698738
Age, Sex, Metabolic and Pharmacologic Factors May Predict Nonresponse Status to Rheumatoid Arthritis Therapies., PMID:37652478
Mitochondria-Related Gene MAOB is a Key Biomarker of Osteoarthritis and Inhibition of Its Expression Reduces LPS-induced Chondrocyte Damage., PMID:37651071
2-Methoxyestradiol and Hydrogen Peroxide as Promising Biomarkers in Parkinson's Disease., PMID:37589832
αKG-driven RNA polymerase II transcription of cyclin D1 licenses malic enzyme 2 to promote cell-cycle progression., PMID:37422761
Dynamic de novo heterochromatin assembly and disassembly at replication forks ensures fork stability., PMID:37414849
NADP-Dependent Malic Enzyme Genes in Sweet Pepper Fruits: Involvement in Ripening and Modulation by Nitric Oxide (NO)., PMID:37375977
Controlled Decompression Alleviates Motor Dysfunction by Regulating Microglial Polarization via the HIF-1α Signaling Pathway in Intracranial Hypertension., PMID:37328678
Cellular redox homeostasis maintained by malic enzyme 2 is essential for MYC-driven T cell lymphomagenesis., PMID:37253016
Reversible binding of divalent cations to Ductin protein assemblies-A putative new regulatory mechanism of membrane traffic processes., PMID:37228584
Mucosal immunization with lactiplantibacillus plantarum-displaying recombinant SARS-CoV-2 epitopes on the surface induces humoral and mucosal immune responses in mice., PMID:37161468
Genome-wide identification and expression profile analysis of metal tolerance protein gene family in Eucalyptus grandis under metal stresses., PMID:37149585
ME2 Promotes Hepatocellular Carcinoma Cell Migration through Pyruvate., PMID:37110198
For research use only. Not for human or drug use.
