Catalog No.
YHD56501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Tyr47-Glu216
Predicted molecular weight
21.16 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P23284
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Cyclophilin B, S-cyclophilin, Rotamase B, PPIase B, CYP-S1, Peptidyl-prolyl cis-trans isomerase B, PPIB, SCYLP, CYPB
Engineering Pt Single-Atom Doped SeS2/Ti3CNTx MXene with Molecularly Imprinted Polymer for Precision Pancreatic Cancer Diagnostics: DFT and Molecular Dynamics Perspectives., PMID:40420649
Optimization of Cyclophilin B-Targeted Tri-vector Inhibitors for Novel MASH Treatments., PMID:40074291
The structural basis for the collagen processing by human P3H1/CRTAP/PPIB ternary complex., PMID:39245686
Sanglifehrin A mitigates multiorgan fibrosis by targeting the collagen chaperone cyclophilin B., PMID:38900587
(2S,4S)-5-Fluoroleucine, (2S,4R)-5-Fluoroleucine, and 5,5'-Difluoroleucine in Escherichia coli PpiB: Protein Production, 19F NMR, and Ligand Sensing Enhanced by the γ-Gauche Effect., PMID:38753308
Optimized expression of Peptidyl-prolyl cis/transisomerase cyclophilinB with prokaryotic toxicity from Sporothrix globosa., PMID:38730558
Repair of CRISPR-guided RNA breaks enables site-specific RNA excision in human cells., PMID:38662916
PPIB/Cyclophilin B expression associates with tumor progression and unfavorable survival in patients with pulmonary adenocarcinoma., PMID:38455410
Mice lacking cyclophilin B, but not cyclophilin A, are protected from the development of NASH in a diet and chemical-induced model., PMID:38427624
Endoplasmic Reticulum Stress and Its Impact on Adipogenesis: Molecular Mechanisms Implicated., PMID:38140341
Autophagy activates EGR1 via MAPK/ERK to induce FGF2 in renal tubular cells for fibroblast activation and fibrosis during maladaptive kidney repair., PMID:37978868
Cyclophilin B serum levels present variations across the menstrual cycle., PMID:37349369
Sanglifehrin A mitigates multi-organ fibrosis in vivo by inducing secretion of the collagen chaperone cyclophilin B., PMID:36945535
Association of cyclophilins and cardiovascular risk factors in coronary artery disease., PMID:36935755
Cyclophilin B, a molecule chaperone, promotes adipogenesis in 3T3‑L1 preadipocytes via AKT/mTOR pathway., PMID:36484370
Extracellular cyclophilins A and C induce dysfunction of pancreatic microendothelial cells., PMID:36277217
High-fat diet induced cyclophilin B enhances STAT3/lncRNA-PVT1 feedforward loop and promotes growth and metastasis in colorectal cancer., PMID:36266267
Accelerated Aging in Cyclophilin B-Deficient Mice Downstream of p21-Cip1/Waf1., PMID:36248275
Human Cyclophilin B Nuclease Activity Revealed via Nucleic Acid-Based Electrochemical Sensors., PMID:35999181
Tubular cells produce FGF2 via autophagy after acute kidney injury leading to fibroblast activation and renal fibrosis., PMID:35491858
FK506-Binding Protein 11 Is a Novel Plasma Cell-Specific Antibody Folding Catalyst with Increased Expression in Idiopathic Pulmonary Fibrosis., PMID:35456020
CircTCF25 serves as a sponge for miR-206 to support proliferation, migration, and invasion of glioma via the Jak2/p-Stat3/CypB axis., PMID:35384084
Cyclophilin B is really a major growth factor in breast milk., PMID:35032767
Cathepsin B is a potential therapeutic target for coronavirus disease 2019 patients with lung adenocarcinoma., PMID:35007526
Connective Tissue Disorders in Domestic Animals., PMID:34807427
Atrial natriuretic peptide promotes uterine decidualization and a TRAIL-dependent mechanism in spiral artery remodeling., PMID:34473650
Identification of a Novel Epithelial-Mesenchymal Transition Gene Signature Predicting Survival in Patients With HNSCC., PMID:34257533
CypB promotes cell proliferation and metastasis in endometrial carcinoma., PMID:34187415
Host factor cyclophilin B affects Orf virus replication by interacting with viral ORF058 protein., PMID:33984791
Honokiol inhibits hepatoma carcinoma cell migration through downregulated Cyclophilin B expression., PMID:33743348
Gene diversity explains variation in biological features of insect killing fungus, Beauveria bassiana., PMID:33420123
fISHing with immunohistochemistry for housekeeping gene changes in Alzheimer's disease using an automated quantitative analysis workflow., PMID:33368239
CypB-CD147 Signaling Is Involved in Crosstalk between Cartilage and FLS in Collagen-Induced Arthritis., PMID:32908452
The combination of hprt and gapdh is the best compound reference genes in the fetal rat hippocampus., PMID:32875725
Amide-Modified RNA: Using Protein Backbone to Modulate Function of Short Interfering RNAs., PMID:32658452
System-wide analyses of the fission yeast poly(A)+ RNA interactome reveal insights into organization and function of RNA-protein complexes., PMID:32554781
Cyclophilin B overexpression predicts a poor prognosis and activates metastatic pathways in colon cancer., PMID:35117721
Crtap and p3h1 knock out zebrafish support defective collagen chaperoning as the cause of their osteogenesis imperfecta phenotype., PMID:32173581
Identification of Salmonella Typhimurium Peptidyl-prolyl cis-trans Isomerase B (PPIase B) and Assessment of their Role in the Protein Folding., PMID:32096737
Inorganic polyphosphate controls cyclophilin B-mediated collagen folding in osteoblast-like cells., PMID:32056376
In-Cell Trityl-Trityl Distance Measurements on Proteins., PMID:31951412
Binding and Internalization in Receptor-Targeted Carriers: The Complex Role of CD44 in the Uptake of Hyaluronic Acid-Based Nanoparticles (siRNA Delivery)., PMID:31738017
Influences of cyclosporin A and non-immunosuppressive derivatives on cellular cyclophilins and viral nucleocapsid protein during human coronavirus 229E replication., PMID:31634494
Genetic manipulation of cell line derived reticulocytes enables dissection of host malaria invasion requirements., PMID:31444345
High Serum Cyclophilin C levels as a risk factor marker for Coronary Artery Disease., PMID:31332225
Peptidyl-Prolyl Isomerase ppiB Is Essential for Proteome Homeostasis and Virulence in Burkholderia pseudomallei., PMID:31331957
Selection of Reference Genes for Normalization of Gene Expression Data in Blood of Machado-Joseph Disease/Spinocerebellar Ataxia Type 3 (MJD/SCA3) Subjects., PMID:31286408
Cyclophilin B control of lysine post-translational modifications of skin type I collagen., PMID:31173582
Cellular stress due to impairment of collagen prolyl hydroxylation complex is rescued by the chaperone 4-phenylbutyrate., PMID:31171565
Plant-Mediated Silencing of the Whitefly Bemisia tabaci Cyclophilin B and Heat Shock Protein 70 Impairs Insect Development and Virus Transmission., PMID:31133883
For research use only. Not for human or drug use.
