Catalog No.
YHD55901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly367-Leu599
Predicted molecular weight
28.84 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P23219
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
COX-1, Prostaglandin-endoperoxide synthase 1, PGH synthase 1, Prostaglandin H2 synthase 1, Cyclooxygenase-1, PHS 1, PTGS1, Prostaglandin G/H synthase 1, COX1, PGHS-1
Puerarin suppresses the oxidative stress and activates the cyclic AMP (cAMP)/cAMP response element binding protein/brain-derived neurotrophic factor signaling pathway in alcohol withdrawal-induced depressive disorder via regulating obesity-associated protein-mediated N6-methyladenosine demethylation., PMID:40470634
Genome-Wide Study of Diabetes Mellitus (Type 2)-Associated Genes in Homo sapiens (Human)., PMID:40462586
Analysis of the Expression and Activity of Cyclooxygenases COX-1 and COX-2 in THP-1 Monocytes and Macrophages Cultured with Xenogenic Collagen Matrices Biofunctionalized with the Injectable Platelet-Rich Fibrin., PMID:40362624
Obesity-related drug-metabolizing enzyme expression alterations in the human liver., PMID:40359692
[Medication rules and mechanisms of treating chronic renal failure by Jinling medical school based on data mining, network pharmacology, and experimental validation]., PMID:40350951
Circadian rhythm and aryl hydrocarbon receptor crosstalk in bone marrow adipose tissue and implications in leukemia., PMID:40350529
Skin mucus proteomic provides insights into the alkaline tolerance of grass carp (Ctenopharyngodon idella)., PMID:40327979
Association between two single nucleotide polymorphisms of the Prostaglandin-Endoperoxide Synthase 1 and 2 genes and cell proliferative prostatic diseases in Lebanon., PMID:40184332
Prostaglandin G/H synthase 1 promotes thrombosis in atrial fibrillation through modulation of platelet activation, macrophage infiltration, inflammation, and autophagy inhibition., PMID:39963884
Granulosa cell expression of Fos is critical for regulating ovulatory gene expressions in the mouse ovary., PMID:39945297
Alteration of COX-1 and TLR4 expression in the mouse brain during chronic social defeat stress revealed by Positron Emission Tomography study., PMID:39929590
Joint exploration of network pharmacology and metabolomics on the effects of traditional Chinese medicine compounds in weaned yaks., PMID:39872609
Beta-sitosterol regulates PTGS1 to inhibit gastric cancer cell proliferation and angiogenesis., PMID:39863019
[Clinical and genetic associations in patients with non-cardioembolic ischemic stroke]., PMID:39831357
[Analysis of Genes Related to Platelet Activation in Essential Thrombocythemia Based on Transcriptomics]., PMID:39743270
Targeting Arachidonic Acid Metabolism Enhances Immunotherapy Efficacy in ARID1A-Deficient Colorectal Cancer., PMID:39652583
Exploration of the Key Pathways and Genes Involved in Osteoarthritis Genesis: Evidence from Multiple Platforms and Real-World Validation., PMID:39649419
The associations of candidate gene polymorphisms with aspirin resistance in patients with ischemic disease: a meta-analysis., PMID:39617913
Spatiotemporal characterization of cyclooxygenase pathway enzymes during vertebrate embryonic development., PMID:39581452
[11C]PS13 Demonstrates Pharmacologically Selective and Substantial Binding to Cyclooxygenase-1 in the Human Brain., PMID:39542698
[Molecular mechanism of high-altitude hypoxia-induced lipid metabolism disorder in mouse spleen tissue]., PMID:39523103
Drug risks associated with sarcopenia: a real-world and GWAS study., PMID:39511635
Integrated Metabolomics and Network Pharmacology Study on the Mechanism of Rehmanniae radix Extract for Treating Thrombosis., PMID:39497835
In organello silencing of mitochondrial gene expression., PMID:39455231
Roburic acid inhibits lung cancer metastasis and triggers autophagy as verified by network pharmacology, molecular docking techniques and experiments., PMID:39450260
Eicosanoid biosynthesizing enzymes in Prototheria., PMID:39389415
Spatiotemporally distinct roles of cyclooxygenase-1 and cyclooxygenase-2 at fetomaternal interface in mice., PMID:39377223
Antioxidant Effect of Naringin Demonstrated Through a Bayes' Theorem Driven Multidisciplinary Approach Reveals its Prophylactic Potential as a Dietary Supplement for Ischemic Stroke., PMID:39352635
Paternal undernutrition and overnutrition modify semen composition and preimplantation embryo developmental kinetics in mice., PMID:39278917
Prenatal Fish Oil Supplementation, Maternal COX1 Genotype, and Childhood Atopic Dermatitis: A Secondary Analysis of a Randomized Clinical Trial., PMID:39196551
Defective mitochondrial COX1 translation due to loss of COX14 function triggers ROS-induced inflammation in mouse liver., PMID:39134548
Identification of key genes and long non‑coding RNA expression profiles in osteoporosis with rheumatoid arthritis based on bioinformatics analysis., PMID:39118036
Exploring the therapeutic effect of core components in Xuanshen Yishen mixture on hypertension through network pharmacology., PMID:39114699
Prostaglandin-related genes are differentially expressed in equine endometrium with different biopsy grade, degrees of inflammation, and fibrosis., PMID:39089078
Magnoflorine alleviates dextran sulfate sodium-induced ulcerative colitis via inhibiting JAK2/STAT3 signaling pathway., PMID:39079890
The human mitochondrial translation factor TACO1 alleviates mitoribosome stalling at polyproline stretches., PMID:39036954
Integrated approach of network pharmacology, molecular docking, and clinical observations in evaluating the efficacy and safety of Bufei Huoxue capsules for pulmonary hypertension associated with chronic obstructive pulmonary disease., PMID:39035784
Network Pharmacology Combined with Bioinformatics Analysis to Texplore the Potential Mechanism of Phellodendri Chinensis Cortex Against Bladder Cancer., PMID:39023680
Clinical and pharmacogenetic features of patients with upper gastrointestinal lesions at a multidisciplinary hospital: the role of nonsteroidal anti-inflammatory drugs., PMID:38996813
Molecular based identification and phylogenetic relationship of the leech Hirudinaria manillensis from India by using mitochondrial cytochrome c oxidase subunit I gene., PMID:38970720
Mechanisms underlying the therapeutic effects of Semen cuscutae in treating recurrent spontaneous abortion based on network pharmacology and molecular docking., PMID:38872917
Integrated Serum Pharmacochemistry, Network Pharmacology, and Molecular Docking to Study the Mechanism of Rhubarb against Atherosclerosis., PMID:38847162
Mechanisms of Tripterygium wilfordii Hook F on treating rheumatoid arthritis explored by network pharmacology analysis and molecular docking., PMID:38841174
Study on the Mechanism of Action of the Traditional Chinese Medical Prescription Gushukang in Treating Osteoporosis Based on Network Pharmacology and Experimental Verification., PMID:38808725
Norcantharidin Enhances the Antitumor Effect of 5-Fluorouracil by Inducing Apoptosis of Cervical Cancer Cells: Network Pharmacology, Molecular Docking, and Experimental Validation., PMID:38785510
Effect of PEAR1, PTGS1 gene polymorphisms on the recurrence of aspirin-treated patients with ischemic stroke in the Han population of China: A 4-year follow-up study., PMID:38728491
ACOX2 Serves as a Favorable Indicator Related to Lipid Metabolism and Oxidative Stress for Biochemical Recurrence in Prostate Cancer., PMID:38706909
Anti-inflammatory and anti-diabetic properties of indanone derivative isolated from Fernandoa adenophylla in vitro and in silico studies., PMID:38671030
Differential Impact In Vivo of Pf4-ΔCre-Mediated and Gp1ba-ΔCre-Mediated Depletion of Cyclooxygenase-1 in Platelets in Mice., PMID:38660804
Antagonistic effects of a COX1/2 inhibitor drug in human HepG2 cells exposed to an environmental carcinogen., PMID:38642625
For research use only. Not for human or drug use.
