Catalog No.
YHD53701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp22-Glu258
Predicted molecular weight
28.28 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P22692
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
IGF-binding protein 4, IBP-4, Insulin-like growth factor-binding protein 4, IGFBP-4, IGFBP4, IBP4
Human placenta mesenchymal stromal cells alleviate intestinal inflammation and repair intestinal barrier function by activating AMPK-FXR pathway., PMID:40447793
Plasma proteomics identify novel biomarkers and dynamic patterns of biological aging., PMID:40328427
The special phenotypic characteristics of Dummerstorf superfertile mouse lines could depend on the expression levels of IGF-axis genes., PMID:40158446
DNA methylation-predicted plasma protein levels and breast cancer risk., PMID:40140843
Causal Effects From Kidney Function to Plasma Proteome: Integrated Observational and Mendelian Randomization Analysis With >50,000 UK Biobank Participants., PMID:40014632
Establishment of an alternative splicing prognostic risk model and identification of FN1 as a potential biomarker in glioblastoma multiforme., PMID:40000711
IGFBP2 and IGFBP4 interact to activate complement pathway in diabetic kidney disease., PMID:39806768
Temporal RAGE Over-Expression Disrupts Lung Development by Modulating Apoptotic Signaling., PMID:39727995
Large-Scale Plasma Proteomics Profiles for Predicting Ischemic Stroke Risk in the General Population., PMID:39704077
MYBBP1A‑mediated IGFBP4 promoter methylation promotes epithelial‑mesenchymal transition and metastasis through activation of NOTCH pathway in liver cancer., PMID:39611481
A Proteomics-Based Approach for Prediction of Different Cardiovascular Diseases and Dementia., PMID:39540306
Developmental and Molecular Effects of C-Type Natriuretic Peptide Supplementation in In Vitro Culture of Bovine Embryos., PMID:39456721
IGF2/IGFBP4 reduces apoptosis and increases free cholesterol of chicken granulosa cells in vitro., PMID:39432993
The pro-atherogenic enzyme PAPP-A is active in eluates from human carotid and femoral atherosclerotic plaques., PMID:39308741
Specific cleavage of IGFBP-4 by papp-a in nervous tissue., PMID:39244846
Association between IGF-1 and IGFBPs in Blood and Follicular Fluid in Dairy Cows Under Field Conditions., PMID:39199904
Dynamic changes in insulin-like growth factor binding protein expression occur between embryonic and early post-hatch development in broiler chickens., PMID:39197338
Immunomodulatory effects of the induced pluripotent stem cells through expressing IGF-related factors and IL-10 in vitro., PMID:39162714
The effects of the feeding duration of propylene glycol on major meat quality parameters and substantial proteins in the muscle of Akkaraman lambs., PMID:39084122
Unveiling the functions of five recently characterized lncRNAs in cancer progression., PMID:39066874
Blackcurrants shape gut microbiota profile and reduce risk of postmenopausal osteoporosis via the gut-bone axis: Evidence from a pilot randomized controlled trial., PMID:39019119
Integrin-Linked Kinase in the Development of Gastric Tumors Induced by Helicobacter pylori: Regulation and Prevention Potential., PMID:38951739
Deciphering smooth muscle cell heterogeneity in atherosclerotic plaques and constructing model: a multi-omics approach with focus on KLF15/IGFBP4 axis., PMID:38760675
STING-deficiency in lung resident mesenchymal stromal cells contributes to the alleviation of LPS-induced lung injury., PMID:38657444
White adipose tissue, a novel antirheumatic target: Clues from its secretory capability and adipectomy-based therapy., PMID:38644540
Validating the ratio of insulin like growth factor binding protein 4 to sex hormone binding globulin as a prognostic predictor of preterm birth in Viet Nam: a case-cohort study., PMID:38584143
Effect of IGFBP-4 during In Vitro Maturation on Developmental Competence of Bovine Cumulus Oocyte Complexes., PMID:38473060
Multiplex Proteomics in the Identification of Potential Biomarkers of Very Severe Sinusoidal Obstruction Syndrome/Veno-Occlusive Disease in Allogeneic Hematopoietic Cell Transplant Patients Treated with Defibrotide., PMID:38330921
Scaling up polarized RPE cell supernatant production on parylene membrane., PMID:38242423
The direct impact of pegvisomant on osteoblast functions and bone development., PMID:38159174
Increased IGFBP Proteolysis, IGF-I Bioavailability, and Pappalysin Levels in Children With Prader-Willi Syndrome., PMID:38141219
Reduction in Pappalysin-2 Levels and Lower IGF-I Bioavailability in Female Adolescents With Anorexia Nervosa., PMID:38066647
Proteomics Analysis of Serum Reveals Potential Biomarkers for Heart Failure Patients with Phlegm-Blood Stasis Syndrome., PMID:38048169
Pomegranate Peel Extract Differently Modulates Gene Expression in Gingiva-Derived Mesenchymal Stromal Cells under Physiological and Inflammatory Conditions., PMID:37895087
Expressions of Insulin-like Growth Factor System among Different Breeds Impact Piglets' Growth during Weaning., PMID:37835617
Integrative analysis of cuproptosis-associated genes for predicting immunotherapy response in single-cell and multi-cohort studies., PMID:37776237
Increased Levels of Circulating IGFBP4 and ANGPTL8 with a Prospective Role in Diabetic Nephropathy., PMID:37762544
IGF-1 axis changes with ADT and docetaxel in metastatic prostate cancer., PMID:37671811
AKAP12 and IGFBP4 Are Prognostic Factors for Chronic Lymphocytic Leukemia., PMID:37605556
Stanniocalcin-2 inhibits skeletal muscle growth and is upregulated in functional overload-induced hypertrophy., PMID:37568262
Circulating miR-4739 and IGFBP-4 Levels in Postmenopausal Women with Osteoporosis and Osteoporotic Vertebral Fracture., PMID:37471661
The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4., PMID:37433992
Runx1 regulates critical factors that control uterine angiogenesis and trophoblast differentiation during placental development., PMID:37416873
FERMT2 upregulation in CAFs enhances EMT of OSCC and M2 macrophage polarization., PMID:37357349
Activation of IGFBP4 via unconventional mechanism of miRNA attenuates metastasis of intrahepatic cholangiocarcinoma., PMID:37349627
The Pregnancy-Associated Plasma Protein-A (PAPP-A) Story., PMID:37267421
Further Evidence that an Episode of Premature Labor Is a Pathologic State: Involvement of the Insulin-Like Growth Factor System., PMID:37231893
PAPP-A-Specific IGFBP-4 Proteolysis in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes., PMID:37176126
Insulin-like growth factor binding Protein-4: A novel indicator of pulmonary arterial hypertension severity and survival., PMID:37152104
Single-Cell RNA Sequencing Reveals Unique Alterations in the Immune Panorama and Treg Subpopulations in Mice during the Late Stages of Echinococcus granulosus Infection., PMID:37039643
For research use only. Not for human or drug use.
