Catalog No.
YHD53101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg21-Gly103
Predicted molecular weight
11.60 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P22626
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Heterogeneous nuclear ribonucleoproteins A2/B1, HNRPA2B1, hnRNP A2/B1, HNRNPA2B1
Identify the co-expressed genes of hypertensive nephropathy and diabetic nephropathy., PMID:40461634
Post-transcriptional regulation of H19 by m6A reader proteins: H19 stability versus miR-675 biogenesis., PMID:40447192
Targeting Redox Signaling Through Exosomal MicroRNA: Insights into Tumor Microenvironment and Precision Oncology., PMID:40427384
Myeloid-specific HNRNPA2B1 deficiency disrupts macrophage function and in vivo responses., PMID:40414614
HNRNPA2B1-mediated m6A modification enhances lncRNA NORHA stability to control granulosa cell functions., PMID:40407136
An integrative systems-biology approach defines mechanisms of Alzheimer's disease neurodegeneration., PMID:40393985
hnRNPA2B1 promotes the production of exosomal miR-103-3p from endothelial progenitor cells to alleviate macrophage M1 polarization in acute respiratory distress syndrome., PMID:40381491
Bioinformatics analysis reveals shared molecular pathways for relationship between ulcerative colitis and primary sclerosing cholangitis., PMID:40375266
New IgG and IgA autoantibody specificities against DNA-binding and RNA-binding proteins discriminate systemic lupus erythematosus from health and non-lupus autoimmunity-could anti-LIN28A enhance precision in diagnostics?, PMID:40374430
The potential of MCM8 as a biomarker in esophageal carcinoma: a comprehensive analysis integrating m6a methylation and angiogenesis., PMID:40346692
The m6A methylation system limits hepatitis B virus replication., PMID:40326019
Computational Exploration of the Inhibitory Mechanism of mRNA against the Phase Separation of hnRNPA2 Low Complexity Domains., PMID:40305655
Peptides based on the interface of hnRNPA2B1-transthyretin complex repress retinal angiogenesis in diabetic retinopathy., PMID:40253339
hnRNPA2B1 facilitates ovarian carcinoma metastasis by sorting cargoes into small extracellular vesicles driving myofibroblasts activation., PMID:40186209
Altered tear fluid protein expression in persons with mild Alzheimer's disease in proteins involved in oxidative stress, protein synthesis, and energy metabolism., PMID:40183343
Cytoplasmic accumulation of a splice variant of hnRNPA2/B1 contributes to FUS-associated toxicity in a mouse model of ALS., PMID:40157939
Effective Immobilization of hnRNPA2B1 Protein in a PEI Layer on a QCM Gold Electrode., PMID:40134223
Spliceosome protein alterations differentiate hubs of the default mode connectome during the progression of Alzheimer's disease., PMID:40122679
Small molecule inhibitors of hnRNPA2B1-RNA interactions reveal a predictable sorting of RNA subsets into extracellular vesicles., PMID:40103230
Myopathic aggregation-prone variants in the TDP-43 prion-like domain: genetics paving the way., PMID:40036368
Exosomal lncRNA Mir100hg from lung cancer stem cells activates H3K14 lactylation to enhance metastatic activity in non-stem lung cancer cells., PMID:40022086
HnRNPA2B1 promotes cardiac ferroptosis via m6A-dependent stabilization of PFN2 mRNA in myocardial ischemia-reperfusion injury., PMID:40010516
Novel Insight of N6-Methyladenosine in Cardiovascular System., PMID:40005339
Mechanistic insights into microwave radiation induced cognitive impairments: The role of m6A epigenetic modifications and HNRNPA2B1 in TrkB regulation., PMID:39999628
HnRNPC triggers the degradation of MITA to suppress the interferon-mediated antiviral response., PMID:39994817
Klotho Regulates Club Cell Senescence and Differentiation in Chronic Obstructive Pulmonary Disease., PMID:39930762
miR-448-3p/miR-1264-3p Participates in Intermittent Hypoxic Response in Hippocampus by Regulating Fam76b/hnRNPA2B1., PMID:39912396
Gut microbe-derived betulinic acid alleviates sepsis-induced acute liver injury by inhibiting macrophage NLRP3 inflammasome in mice., PMID:39887250
Targeting HNRNPA2B1 to overcome chemotherapy resistance in gastric cancer stem cells: Mechanisms and therapeutic potential., PMID:39870196
A mitochondria-to-nucleus regulation mediated by the nuclear-translocated mitochondrial lncRNAs., PMID:39869642
Mechanistic insights into HNRNPA2B1: A comprehensive pan-cancer analysis and functional characterization in lung cancer., PMID:39826851
hsa_circ_0001599 promotes odontogenic differentiation of human dental pulp stem cells by increasing ITGA2 expression and stability., PMID:39825107
Nuclear adenine activates hnRNPA2B1 to enhance antibacterial innate immunity., PMID:39814017
hnRNPA2B1 drives colorectal cancer progression via the circCDYL/EIF4A3/PHF8 axis., PMID:39810713
LIN28A-dependent lncRNA NEAT1 aggravates sepsis-induced acute respiratory distress syndrome through destabilizing ACE2 mRNA by RNA methylation., PMID:39762837
Exosome-derived long non-coding RNA AC010789.1 modified by FTO and hnRNPA2B1 accelerates growth of hair follicle stem cells against androgen alopecia by activating S100A8/Wnt/β-catenin signalling., PMID:39748192
Single-cell RNA sequencing reveals the critical role of alternative splicing in cattle testicular spermatagonia., PMID:39726007
Exosome-delivered NR2F1-AS1 and NR2F1 drive phenotypic transition from dormancy to proliferation in treatment-resistant prostate cancer via stabilizing hormonal receptors., PMID:39695778
m6A-related genes ALKBH5 and RBMX as prognostic and progression biomarkers in Chinese oral squamous cell carcinoma patients., PMID:39643954
Exosomal linc00152 intensifies the crosstalk between cholangiocarcinoma cells and cancer-associated fibroblasts., PMID:39615627
Knockdown of RUVBL2 improves hnRNPA2/B1-stress granules dynamics to inhibit perioperative neurocognitive disorders in aged mild cognitive impairment rats., PMID:39610020
hnRNPA2B1 deacetylation by SIRT6 restrains local transcription and safeguards genome stability., PMID:39511404
m6A-modified exosome-derived circHIF1α binding to KH domain of IGF2BP3 mediates DNA damage and arrests G1/S transition phase to resists bacterial infection in bacteremia., PMID:39443946
N6-methyladenosine (m6A) reader HNRNPA2B1 accelerates the cervical cancer cells aerobic glycolysis., PMID:39425888
CEP112 coordinates translational regulation of essential fertility genes during spermiogenesis through phase separation in humans and mice., PMID:39349455
Exosome-related gene identification and diagnostic model construction in hepatic ischemia-reperfusion injury., PMID:39341981
Decellularized adipose-derived matrix from Superficial layers of abdominal adipose tissue exhibits superior capacity of adipogenesis compared to deep layers., PMID:39318374
lncRNA H19 plays a role in multiple myeloma via interacting with hnRNPA2B1 to stabilize BET proteins by targeting osteoclasts and osteoblasts., PMID:39288624
The Potential Impact of HNRNPA2B1 on Human Cancers Prognosis and Immune Microenvironment., PMID:39268079
The RNA binding protein HNRNPA2B1 regulates RNA abundance and motor protein activity in neurites., PMID:39253515
For research use only. Not for human or drug use.
