Catalog No.
YHD52801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser33-Arg219
Predicted molecular weight
22.71 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P22570
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ADXR, Adrenodoxin reductase, NADPH:adrenodoxin oxidoreductase, mitochondrial, Ferredoxin reductase, Ferredoxin--NADP(+) reductase, FDXR, AR
A molecular basis of Ferredoxin Reductase (FdxR) mutations that result in mitochondriopathies., PMID:40479788
Biallelic FDXR mutations induce ferroptosis in a rare mitochondrial disease with ataxia., PMID:39954867
Disordered Electron Transfer: New Forms of Defective Steroidogenesis and Mitochondriopathy., PMID:39574227
Unraveling the molecular determinants of a rare human mitochondrial disorder caused by the P144L mutation of FDX2., PMID:39467201
Clinical and genetic landscape of optic atrophy in 826 families: insights from 50 nuclear genes., PMID:39423307
Validation of a blood biomarker panel for machine learning-based radiation biodosimetry in juvenile and adult C57BL/6 mice., PMID:39396080
Identification of BBC3 as a novel indicator for predicting prostate cancer development and olaparib resistance., PMID:39331229
Unique features of KGN granulosa-like tumour cells in the regulation of steroidogenic and antioxidant genes., PMID:39110703
Identification of chemoresistance targets in doxorubicin-resistant lung adenocarcinoma cells using LC-MS/MS-based proteomics., PMID:39101797
Biomarkers for Radiation Biodosimetry and Correlation with Hematopoietic Injury in a Humanized Mouse Model., PMID:39034036
Investigation of copper-induced intestinal damage and proteome alterations in Takifugu rubripes: Potential health risks and environmental toxicology detection., PMID:39024957
Expression levels of the selenium-uptake receptor LRP8, the antioxidant selenoprotein GPX1 and steroidogenic enzymes correlate in granulosa cells., PMID:38990713
FDXR variants cause adrenal insufficiency and atypical sexual development., PMID:38885337
Ferredoxin 1 is essential for embryonic development and lipid homeostasis., PMID:38251655
CXCL10 upregulation in radiation-exposed human peripheral blood mononuclear cells as a candidate biomarker for rapid triage after radiation exposure., PMID:38227479
UCHL1 deficiency upon HCMV infection induces vascular endothelial inflammatory injury mediated by mitochondrial iron overload., PMID:38081437
Single-Cell RNA-Seq Identifies Pathways and Genes Contributing to the Hyperandrogenemia Associated with Polycystic Ovary Syndrome., PMID:37445796
The DNA damage response to radiological imaging: from ROS and γH2AX foci induction to gene expression responses in vivo., PMID:37335333
Candidate Gene Expression in Regional Population and Its Relevance for Radiation Triage., PMID:37253332
FDXR-associated disease: a challenging differential diagnosis with inflammatory peripheral neuropathy., PMID:37046037
Effects of Neutron and Gamma Rays Combined Irradiation on the Transcriptional Profile of Human Peripheral Blood., PMID:37014889
Machine learning approach for quantitative biodosimetry of partial-body or total-body radiation exposures by combining radiation-responsive biomarkers., PMID:36653416
Four Genes Predictive for the Severity of Hematological Damage Reveal a Similar Response after X Irradiation and Chemotherapy., PMID:36480042
The top 10 most frequently involved genes in hereditary optic neuropathies in 2186 probands., PMID:36317462
FDXR Gene Expression after in Vivo Radiation Exposure of Pediatric Patients Undergoing Interventional Cardiology Procedures., PMID:36224003
Therapeutic Targeting of Ovarian Cancer Stem Cells Using Estrogen Receptor Beta Agonist., PMID:35806169
Reduced serum high-density lipoprotein cholesterol levels and aberrantly expressed cholesterol metabolism genes in colorectal cancer., PMID:35663062
Ferredoxin reductase and p53 are necessary for lipid homeostasis and tumor suppression through the ABCA1-SREBP pathway., PMID:35121827
Proteomic profiling of cisplatin-resistant and cisplatin-sensitive germ cell tumour cell lines using quantitative mass spectrometry., PMID:35084545
A 4-Gene Signature of CDKN1, FDXR, SESN1 and PCNA Radiation Biomarkers for Prediction of Patient Radiosensitivity., PMID:34638945
Gene expression changes and DNA damage after ex vivo exposure of peripheral blood cells to various CT photon spectra., PMID:34103547
Ferredoxin reductase regulates proliferation, differentiation, cell cycle and lipogenesis but not apoptosis in SZ95 sebocytes., PMID:34090862
Biological dosimetry and modern (-omic) methods., PMID:33445934
Exposure of patients to low doses of X-radiation during neuro-interventional imaging and procedures: Dose estimation and analysis of γ-H2AX foci and gene expression in blood lymphocytes., PMID:32928370
Mitochondrial [4Fe-4S] protein assembly involves reductive [2Fe-2S] cluster fusion on ISCA1-ISCA2 by electron flow from ferredoxin FDX2., PMID:32817474
Integrated analysis of the molecular pathogenesis of FDXR-associated disease., PMID:32499495
PHA stimulation may be useful for FDXR gene expression-based biodosimetry., PMID:32489559
FDXR regulates TP73 tumor suppressor via IRP2 to modulate aging and tumor suppression., PMID:32304229
Transcriptomic analysis of female and male gonads in juvenile snakeskin gourami (Trichopodus pectoralis)., PMID:32251302
CT Irradiation-induced Changes of Gene Expression within Peripheral Blood Cells., PMID:32167501
Omics-based integrated analysis identified ATRX as a biomarker associated with glioma diagnosis and prognosis., PMID:31908895
Generation of a Transcriptional Radiation Exposure Signature in Human Blood Using Long-Read Nanopore Sequencing., PMID:31829904
The hunt for radiation biomarkers: current situation., PMID:31829779
Iron regulatory protein 2 is a suppressor of mutant p53 in tumorigenesis., PMID:31332290
DNA damage and gene expression changes in patients exposed to low-dose X-radiation during neuro-interventional radiology procedures., PMID:31326035
RAPID GENE EXPRESSION BASED DOSE ESTIMATION FOR RADIOLOGICAL EMERGENCIES., PMID:31137037
Fhit-Fdxr interaction in the mitochondria: modulation of reactive oxygen species generation and apoptosis in cancer cells., PMID:30770797
Measurement of γ-H2AX foci, miRNA-101, and gene expression as a means to quantify radiation-absorbed dose in cancer patients who had undergone radiotherapy., PMID:30467642
Biallelic mutations in FDXR cause neurodegeneration associated with inflammation., PMID:30250212
Gene expression changes in human iPSC-derived cardiomyocytes after X-ray irradiation., PMID:30247079
For research use only. Not for human or drug use.
