Catalog No.
YHD50401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu3835-Asp4088
Predicted molecular weight
54.59 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P22105
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Hexabrachion-like protein, TNX, TNXB, XB, HXBL, TN-X, TNXB1, TNXB2, Tenascin-X
Proteomic analysis reveals potential biomarker candidates in serous ovarian tumors - a preliminary study., PMID:40330446
Multi-omics reveal the role of nociception-related genes TNXB, CTNND1 and CBL in depression., PMID:40286918
Identification and validation of depression-associated genetic variants in the UK Biobank cohort with transcriptome and DNA methylation analyses in independent cohorts., PMID:39897774
Novel genetic insight for psoriasis: integrative genome-wide analyses in 863 080 individuals and proteome-wide Mendelian randomization., PMID:39883516
High clinical utility of long-read sequencing for precise diagnosis of congenital adrenal hyperplasia in 322 probands., PMID:39810276
Identifying prioritization of therapeutic targets for ankylosing spondylitis: a multi-omics Mendelian randomization study., PMID:39707330
[Detection and characterization of the types of CYP21A1P/CYP21A2 and TNXA/TNXB fused genes by long-read sequencing among children with Steroid 21-hydroxylase deficiency]., PMID:39653346
Long-Read Sequencing Identifying the Genetic Complexity of Congenital Adrenal Hyperplasia in the Pedigree., PMID:39575462
First-Trimester Preeclampsia-Induced Disturbance in Maternal Blood Serum Proteome: A Pilot Study., PMID:39408980
Identifying new biomarkers and potential therapeutic targets for breast cancer through the integration of human plasma proteomics: a Mendelian randomization study and colocalization analysis., PMID:39351539
Whole-genome sequencing analysis reveals new susceptibility loci and structural variants associated with progressive supranuclear palsy., PMID:39152475
Shared genetics and causal association between plasma levels of SARS-CoV-2 entry receptor ACE2 and Alzheimer's disease., PMID:39056224
Long-Read Sequencing Solves Complex Structure of CYP21A2 in a Large 21-Hydroxylase Deficiency Cohort., PMID:39049755
Identification of novel drug targets for multiple sclerosis by integrating plasma genetics and proteomes., PMID:38964432
Loss of Smooth Muscle Tenascin-X Inhibits Vascular Remodeling Through Increased TGF-β Signaling., PMID:38934115
Integrated proteomics and metabolomics analysis of sclerosis-related proteins and femoral head necrosis following internal fixation of femoral neck fractures., PMID:38851808
Genetic associations in ankylosing spondylitis: circulating proteins as drug targets and biomarkers., PMID:38835753
Aberrant methylation and expression of TNXB promote chondrocyte apoptosis and extracullar matrix degradation in hemophilic arthropathy via AKT signaling., PMID:38819423
Secretory Phenotype in Peripheral Blood Mononuclear Cells of Elderly Patients with Rheumatoid Arthritis., PMID:38814828
Epigenetic mechanisms of osteoarthritis risk in human skeletal development., PMID:38766055
Tenascin-X is increased with decreased expression of miR-378a-5p and miR-486-5p in mice fed a methionine-choline-deficient diet that induces hepatic fibrosis., PMID:38556264
Case report: A novel compound heterozygous variant in the TNXB gene causes single kidney agenesis and vesicoureteral reflux., PMID:38370350
Evaluating the efficacy of a long-read sequencing-based approach in the clinical diagnosis of neonatal congenital adrenocortical hyperplasia., PMID:38307397
Whole-Genome Sequencing Analysis Reveals New Susceptibility Loci and Structural Variants Associated with Progressive Supranuclear Palsy., PMID:38234807
Impact of Maternal Mediterranean-Type Diet Adherence on Microbiota Composition and Epigenetic Programming of Offspring., PMID:38201877
Genetic determinants of complement activation in the general population., PMID:38159276
Genetic variants identified in novel candidate genes for anorexia nervosa and analysis of molecular pathways for diagnostic applications., PMID:38112957
Hypersensitivity of myelinated A-fibers via toll-like receptor 5 promotes mechanical allodynia in tenascin-X-deficient mice associated with Ehlers-Danlos syndrome., PMID:37898719
Targeted long-read sequencing for comprehensive detection of CYP21A2 mutations in patients with 21-hydroxylase deficiency., PMID:37815751
A MinION-based Long-Read Sequencing Application With One-Step PCR for the Genetic Diagnosis of 21-Hydroxylase Deficiency., PMID:37804107
Epigenome-wide association study identifies Vogt-Koyanagi-Harada disease-associated DNA methylation loci in Chinese., PMID:37394087
Transcriptome Analysis Identifies Biomarkers for the Diagnosis and Management of Psoriasis Complicated with Depression., PMID:37223217
Impact of high-intensity interval training on tendon related gene expression in rat Achilles tendon., PMID:37030065
Circular RNA PDK1 targets miR-4731-5p to enhance TNXB expression in ligamentum flavum hypertrophy., PMID:37014317
Tenascin-X as a causal gene for classical-like Ehlers-Danlos syndrome., PMID:37007968
Pseudogene TNXA Variants May Interfere with the Genetic Testing of CAH-X., PMID:36833192
A Genome-Wide Association Study Identified Novel Genetic Susceptibility Loci for Oral Cancer in Taiwan., PMID:36769103
Patient-specific identification of genome-wide DNA-methylation differences between intracranial and extracranial melanoma metastases., PMID:36624125
Targeted Methylation Profiling of Single Laser-Capture Microdissected Post-Mortem Brain Cells by Adapted Limiting Dilution Bisulfite Pyrosequencing (LDBSP)., PMID:36555213
Integrated proteome and phosphoproteome analysis of gastric adenocarcinoma reveals molecular signatures capable of stratifying patient outcome., PMID:36520032
Network module function enrichment analysis of lung squamous cell carcinoma and lung adenocarcinoma., PMID:36451444
Bioinformatics Analysis of RNA-seq Data Reveals Genes Related to Cancer Stem Cells in Colorectal Cancerogenesis., PMID:36362041
Salt-wasting congenital adrenal hyperplasia phenotype as a result of the TNXA/TNXB chimera 1 (CAH-X CH-1) and the pathogenic IVS2-13A/C > G in CYP21A2 gene., PMID:36264454
Congenital adrenal hyperplasia with a CYP21A2 deletion overlapping the tenascin-X gene: an atypical presentation., PMID:36259452
Proteomics and liquid biopsy characterization of human EMT-related metastasis in colorectal cancer., PMID:36249004
Single-cell analysis reveals heterogeneity of juvenile idiopathic arthritis fibroblast-like synoviocytes with implications for disease subtype., PMID:36167601
Genome-Wide Placental Gene Methylations in Gestational Diabetes Mellitus, Fetal Growth and Metabolic Health Biomarkers in Cord Blood., PMID:35721735
The AGT epistasis pattern proposed a novel role for ZBED9 in regulating blood pressure: Tehran Cardiometabolic genetic study (TCGS)., PMID:35577038
CAH-X Syndrome: Genetic and Clinical Profile., PMID:35476220
Tenascin-X Mediates Flow-Induced Suppression of EndMT and Atherosclerosis., PMID:35443807
For research use only. Not for human or drug use.
