Catalog No.
YHD50001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asp264-Thr497
Predicted molecular weight
28.98 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P22083
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Alpha-(1,3)-fucosyltransferase 4, ELAM-1 ligand fucosyltransferase, Fucosyltransferase 4, Fucosyltransferase IV, Galactoside 3-L-fucosyltransferase, Fuc-TIV, FCT3A, FUT4, ELFT, FucT-IV
Usefulness of CD56, BRAF and CD15 in the differential diagnosis of thyroid lesions with nuclear features of papillary carcinoma., PMID:40424929
Unique N-glycosylation signatures in human iPSC derived microglia activated by Aβ oligomer and lipopolysaccharide., PMID:40210651
Fucosylated haptoglobin promotes inflammation via Mincle in sepsis: an observational study., PMID:39904983
Fucosyltransferase 4 upregulates P-gp expression for chemoresistance via NF-κB signaling pathway., PMID:39725242
Avelumab reduces STAT3 expression with effects on IL-17RA and CD15., PMID:39480959
Focusing on tumor and it's microenvironmental immune members for head and neck cancer patients., PMID:39236499
FUT4 promotes the progression of Cholangiocarcinoma by modulating epithelial-mesenchymal transition., PMID:38466946
Silencing FUT4 Inhibits the Progression of Osteosarcoma through Activation of FOXO1., PMID:38343056
Androgen drives melanoma invasiveness and metastatic spread by inducing tumorigenic fucosylation., PMID:38326303
CD15 Is a Risk Predictor and a Novel Target in Clear Cell Renal Cell Carcinoma., PMID:37963432
α1,3-fucosylation of MEST promotes invasion potential of cytotrophoblast cells by activating translation initiation., PMID:37798282
Tiliroside Combined with Anti-MUC1 Monoclonal Antibody as Promising Anti-Cancer Strategy in AGS Cancer Cells., PMID:37685842
ST3GalIV drives SLeX biosynthesis in gastrointestinal cancer cells and associates with cancer cell motility., PMID:37074623
X-ray inhibits FUT4-mediated proliferation in A549 cells by downregulating SP1 expression., PMID:36932748
Sialyl Lewis X mediates interleukin-1 beta-induced trophoblast adhesion to endometrial cells during human embryo implantation., PMID:36648484
p-Coumaric acid, Kaempferol, Astragalin and Tiliroside Influence the Expression of Glycoforms in AGS Gastric Cancer Cells., PMID:35955735
Targeting Aberrantly Elevated Sialyl Lewis A as a Potential Therapy for Impaired Endometrial Selection Ability in Unexplained Recurrent Miscarriage., PMID:35837404
RP11-867G2.8 promotes EMT and chordoma malignant phenotypes by enhancing FUT4 mRNA stability and translation., PMID:35411246
Sesquiterpene Lactones Attenuate Paclitaxel Resistance Via Inhibiting MALAT1/STAT3/ FUT4 Axis and P-Glycoprotein Transporters in Lung Cancer Cells., PMID:35281907
Altered mRNA Expression of Fucosyltransferases and Fucosidase Predicts Prognosis in Human Oral Carcinoma., PMID:34703796
Anti-Cancer Potential of Afzelin towards AGS Gastric Cancer Cells., PMID:34681197
miR-371b-5p-Engineered Exosomes Enhances Tumor Inhibitory Effect., PMID:34671604
Partners in crime: The Lewis Y antigen and fucosyltransferase IV in Helicobacter pylori-induced gastric cancer., PMID:34571111
The possible association of clusterin fucosylation changes with male fertility disorders., PMID:34341430
Long noncoding RNA TUG1 regulates degradation of chondrocyte extracellular matrix via miR-320c/MMP-13 axis in osteoarthritis., PMID:33981845
Anti-cancer effect of combined action of anti-MUC1 and rosmarinic acid in AGS gastric cancer cells., PMID:33930385
MiR-200c/FUT4 axis prevents the proliferation of colon cancer cells by downregulating the Wnt/β-catenin pathway., PMID:33397320
Systematic construction and validation of an epithelial-mesenchymal transition risk model to predict prognosis of lung adenocarcinoma., PMID:33340396
Activation of CXCL12-CXCR4 signalling induces conversion of immortalised embryonic kidney cells into cancer stem-like cells., PMID:33150801
FUT4siRNA augments the chemosensitivity of non-small cell lung cancer to cisplatin through activation of FOXO1-induced apoptosis., PMID:32948132
MMP2 as an independent prognostic stratifier in oral cavity cancers., PMID:32934875
Fucosyltransferase 4 shapes oncogenic glycoproteome to drive metastasis of lung adenocarcinoma., PMID:32629386
Expression of the cancer stem cell marker SSEA1 is associated with poor survival in metastatic high-grade serous carcinoma., PMID:32472195
Identification of co-expressed genes associated with MLL rearrangement in pediatric acute lymphoblastic leukemia., PMID:32347296
SMYD2 facilitates cancer cell malignancy and xenograft tumor development through ERBB2-mediated FUT4 expression in colon cancer., PMID:32342276
Exosomal MALAT1 sponges miR-26a/26b to promote the invasion and metastasis of colorectal cancer via FUT4 enhanced fucosylation and PI3K/Akt pathway., PMID:32209115
Role of fucosyltransferase IV in the migration and invasion of human melanoma cells., PMID:31961483
The potential function of endometrial-secreted factors for endometrium remodeling during the estrous cycle., PMID:31909524
LncRNA HOXB-AS1 promotes cell growth in multiple myeloma via FUT4 mRNA stability by ELAVL1., PMID:31886581
Long noncoding RNA GAS6-AS2 sponges microRNA-493, thereby enhancing the malignant characteristics of breast cancer cells via upregulation of FUT4., PMID:31839366
MyoD1 suppresses cell migration and invasion by inhibiting FUT4 transcription in human gastric cancer cells., PMID:31831855
Carcinoembryonic antigen is a sialyl Lewis x/a carrier and an E‑selectin ligand in non‑small cell lung cancer., PMID:31793656
Long noncoding RNA AC114812.8 promotes the progression of bladder cancer through miR-371b-5p/FUT4 axis., PMID:31706102
Fucosyltransferase 4 and 7 mediates adhesion of non-small cell lung cancer cells to brain-derived endothelial cells and results in modification of the blood-brain-barrier: in vitro investigation of CD15 and CD15s in lung-to-brain metastasis., PMID:31104223
MiR-29b/Sp1/FUT4 axis modulates the malignancy of leukemia stem cells by regulating fucosylation via Wnt/β-catenin pathway in acute myeloid leukemia., PMID:31097000
Effect of miR-200c on the proliferation, migration and invasion of breast cancer cells and relevant mechanisms., PMID:30941952
The challenge of determining the impact of FUT3 tumor-associated polymorphism rs2306969 (-6951 C> T) in invasive breast cancer cells., PMID:30929162
The role of the mobile proton in fucose migration., PMID:30826852
[Expression of Ikaros and FUT4 in Children's Acute Lymphoblastic Leukemia and Their Relationship]., PMID:30738439
Alternative splicing of Ikaros regulates the FUT4/LeX-α5β1 integrin-FAK axis in acute lymphoblastic leukemia., PMID:30683310
For research use only. Not for human or drug use.
