Anti-CDKN1C Antibody (R3M17)

Catalog No.

RHE73803

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000, IHC: 1:200-1:1000, WB: 1:500-1:2000

Target

Cyclin-dependent kinase inhibitor 1C, KIP2, CDKN1C, Cyclin-dependent kinase inhibitor p57, p57Kip2

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P49918

Applications

ELISA, FCM, IF, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R3M17

Role of p57KIP2 in Stem and Progenitor Leydig Cells of Mouse Testes., PMID:38772531

Machine Learning-Based Single Cell and Integrative Analysis Reveals That Baseline mDC Predisposition Correlates With Hepatitis B Vaccine Antibody Response., PMID:34777332

Pathogenic Germline Variants in Cancer Susceptibility Genes in Children and Young Adults With Rhabdomyosarcoma., PMID:34095712

Long non-coding RNA linc00665 inhibits CDKN1C expression by binding to EZH2 and affects cisplatin sensitivity of NSCLC cells., PMID:33664990

Identification of Chromatin Binding Sites for Long Noncoding RNAs by Chromatin Oligo-Affinity Precipitation (ChOP)., PMID:32681502

p57 in Hydatidiform Moles: Evaluation of Antibodies and Expression in Various Cell Types., PMID:31567274

The hepatic effects in dams that ingested 2-aminoanthracene during gestation and lactation., PMID:31558114

P57-mediated autophagy promotes the efficacy of EGFR inhibitors in hepatocellular carcinoma., PMID:30178471

Crim1 is required for maintenance of the ocular lens epithelium., PMID:29458060

Notch signaling indirectly promotes chondrocyte hypertrophy via regulation of BMP signaling and cell cycle arrest., PMID:27146698

In Vitro Corticogenesis from Embryonic Stem Cells Recapitulates the In Vivo Epigenetic Control of Imprinted Gene Expression., PMID:27095822

Glomerular parietal epithelial cells contribute to adult podocyte regeneration in experimental focal segmental glomerulosclerosis., PMID:25993321

Evidence of an oncogenic role of aberrant TOX activation in cutaneous T-cell lymphoma., PMID:25548321

The expression of cell cycle related proteins PCNA, Ki67, p27 and p57 in normal and preeclamptic human placentas., PMID:24852133

Immunolocalization of cell cycle proteins (p57, p27, cyclin D3, PCNA and Ki67) in intrauterine growth retardation (IUGR) and normal human term placentas., PMID:24252562

[Expression of p57 marker in differential diagnosis of complete and partial mole - correlation with DNA analysis]., PMID:23121032

CDKN1C/P57 is regulated by the Notch target gene Hes1 and induces senescence in human hepatocellular carcinoma., PMID:22705236

Identification of a preneoplastic gene expression profile in tubal epithelium of BRCA1 mutation carriers., PMID:21170264

Transcription factor GATA-3 is essential for lens development., PMID:19623612

Significance of p57(Kip2) down-regulation in oncogenesis of bladder carcinoma: an immunohistochemical study., PMID:18822693

Role of cell and matrix-bound VEGF isoforms in lens development., PMID:18757513

Role of DNA content analysis and immunohistochemistry in the evaluation of the risk of unfavourable outcome in Wilms' tumours., PMID:18507016

Cell cycle genes PEDF and CDKN1C in growing deer antlers., PMID:17610257

The P-glycoprotein (ABCB1) linker domain encodes high-affinity binding sequences to alpha- and beta-tubulins., PMID:17530867

Disappearance of p27(KIP1) and increase in proliferation of the lens cells after extraction of most of the fiber cells of the lens., PMID:16020276

Clinicopathologic and immunohistochemical differences in complete and partial hydatidiform moles in a multiracial Malaysian population., PMID:15968205

Expression of p57KIP2 in infantile hemangioma., PMID:15900410

Immunohistochemical characterization of p57Kip2 expression in tetraploid hydropic placentas., PMID:15270611

Involvement of p27KIP1 in the proliferation of the developing corneal endothelium., PMID:15223790

[Proliferative regulation in the cornea and lens]., PMID:14661541

E-cadherin-dependent intercellular adhesion enhances chemoresistance., PMID:14532995

Refining the diagnosis of hydatidiform mole: image ploidy analysis and p57KIP2 immunohistochemistry., PMID:14511255

The product of the imprinted gene IPL marks human villous cytotrophoblast and is lost in complete hydatidiform mole., PMID:13129680

Immunohistochemical characterization of p57(KIP2) expression in early hydatidiform moles., PMID:12514787

Increased expression of vascular endothelial growth factor in placentas of p57(Kip2) null embryos., PMID:12482580

Inactivation of p57KIP2 by regional promoter hypermethylation and histone deacetylation in human tumors., PMID:11965547

Proliferation in the posterior region of the lens of c-maf-/- mice., PMID:11840349

Identification and functional characterization of an intragenic DNA binding site for the spumaretroviral trans-activator in the human p57Kip2 gene., PMID:11815601

p57(KIP2) expression in normal islet cells and in hyperinsulinism of infancy., PMID:11723059

Discrimination of complete hydatidiform mole from its mimics by immunohistochemistry of the paternally imprinted gene product p57KIP2., PMID:11688455

Dynamic temporal and spatial regulation of the cdk inhibitor p57(kip2) during embryo morphogenesis., PMID:11677056

Spatial and temporal expression patterns of the cyclin-dependent kinase (CDK) inhibitors p27Kip1 and p57Kip2 during mouse development., PMID:11218061

The p57Kip2 cyclin kinase inhibitor is expressed by a restricted set of amacrine cells in the rodent retina., PMID:11135238

Growth and differentiation of human lens epithelial cells in vitro on matrix., PMID:11053292

Differential expression of cyclin-dependent kinase inhibitors in human glomerular disease: role in podocyte proliferation and maturation., PMID:10916090

Induction of cellular genes is mediated by the Bel1 transactivator in foamy virus-infected human cells., PMID:10775579

Basonuclin in murine corneal and lens epithelia correlates with cellular maturation and proliferative ability., PMID:10653358

Functional analysis of the p57KIP2 gene mutation in Beckwith-Wiedemann syndrome., PMID:10323243

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