Catalog No.
YHD48301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Glu169-Asp359
Predicted molecular weight
24.38 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P21854
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CD72, Lyb-2, B-cell differentiation antigen CD72
Cell-surface proteomic profiling identifies CD72 as a regulator of microglial tiling., PMID:40501958
DBI as a Novel Immunotherapeutic Candidate in Colorectal Cancer: Dissecting Genetic Risk and the Immune Landscape via GWAS, eQTL, and pQTL., PMID:40426943
Proteomic associations with fluctuation and long-term changes in BMI: A 40-year follow-up study., PMID:40344339
A cohort of highly activated CD99- CD72+ B cells promoting autoimmune progression in juvenile systemic lupus erythematosus., PMID:40090085
Proteomic associations with fluctuation and long-term changes in BMI: A 40-year follow-up study., PMID:39974069
Soluble CD72 concurrently impairs T cell functions while enhances inflammatory response in sepsis., PMID:39793226
Elucidation of mechanisms underlying active oxygen burst in Citrus sinensis after Diaporthe citri infection using transcriptome analysis., PMID:39268534
Characterization of prostate macrophage heterogeneity, foam cell markers, and CXCL17 upregulation in a mouse model of steroid hormone imbalance., PMID:39251671
Novel Immunotherapy Targets for Relapsed/Refractory B-ALL: A Literature Review., PMID:39222522
A Predictive Model for Initial Platinum-Based Chemotherapy Efficacy in Patients with Postoperative Epithelial Ovarian Cancer Using Tissue-Derived Small Extracellular Vesicles., PMID:39104279
Soluble CD72, is a T-cell activator probably via binding to CD6 in homeostasis and autoimmunity., PMID:39026665
Differential Gene Expression Involved in Bone Turnover of Mice Expressing Constitutively Active TGFβ Receptor Type I., PMID:38892016
CD72 is an inhibitory pattern recognition receptor that recognizes ribosomes and suppresses production of anti-ribosome autoantibody., PMID:38754236
Asiaticoside alleviates lipopolysaccharide-induced acute lung injury by blocking Sema4D/CD72 and inhibiting mitochondrial dysfunction in RAW264.7 cell and mice., PMID:38664244
A phase 1/2 study of pepinemab in children, adolescents, or young adults with recurrent or refractory solid tumors: A children's oncology group consortium report (ADVL1614)., PMID:38520670
Physiological regulation of microalgae under cadmium stress and response mechanisms of time-series analysis using metabolomics., PMID:38262539
Framework humanization optimizes potency of anti-CD72 nanobody CAR-T cells for B-cell malignancies., PMID:38007238
CD72, a new immune checkpoint molecule, is a novel prognostic biomarker for kidney renal clear cell carcinoma., PMID:37980541
CD72 is a pan-tumor antigen associated to pediatric acute leukemia., PMID:37876342
Antigen-presenting autoreactive B cells activate regulatory T cells and suppress autoimmune arthritis in mice., PMID:37695523
Activation and pro-inflammatory cytokine production by unswitched memory B cells during SARS-CoV-2 infection., PMID:37638016
Oncolytic attenuated measles virus encoding NY-ESO-1 induces HLA I and II presentation of this tumor antigen by melanoma and dendritic cells., PMID:37466668
Phosphorylation stabilized TET1 acts as an oncoprotein and therapeutic target in B cell acute lymphoblastic leukemia., PMID:36989375
The Differentially Expressed Genes Responsible for the Development of T Helper 9 Cells From T Helper 2 Cells in Various Disease States: Immuno-Interactomics Study., PMID:38935935
Naturally selected CD7 CAR-T therapy without genetic editing demonstrates significant antitumour efficacy against relapsed and refractory acute myeloid leukaemia (R/R-AML)., PMID:36517851
CD72-semaphorin3A axis: A new regulatory pathway in systemic lupus erythematosus., PMID:36470209
Regulation of B cell receptor signalling by Epstein-Barr virus nuclear antigens., PMID:36383217
Blockage of CD72 reduces B cell proliferation in immune thrombocytopenic purpura, involving interleukin 1 and macrophage migration inhibitory factor secretion., PMID:36326455
Locally Secreted Semaphorin 4D Is Engaged in Both Pathogenic Bone Resorption and Retarded Bone Regeneration in a Ligature-Induced Mouse Model of Periodontitis., PMID:35628440
Dual-Function Semaphorin 4D Released by Platelets: Suppression of Osteoblastogenesis and Promotion of Osteoclastogenesis., PMID:35328359
Role of inhibitory B cell co-receptors in B cell self-tolerance to non-protein antigens., PMID:34989000
Aberrant expression of inhibitory receptors on B cells in patients with Graves' disease., PMID:34933777
[Relapsing-remitting multiple sclerosis: clinical and immunological aspects of the pathology on the example of molecules Sema4D and CD72]., PMID:34387451
Dermatan Sulfate Is a Potential Regulator of IgH via Interactions With Pre-BCR, GTF2I, and BiP ER Complex in Pre-B Lymphoblasts., PMID:34113352
Single-cell transcriptomic analyses of cardiac immune cells reveal that Rel-driven CD72-positive macrophages induce cardiomyocyte injury., PMID:34100920
Semaphorin 4D as a guidance molecule in the immune system., PMID:33787446
Surface Proteomics Reveals CD72 as a Target for In Vitro-Evolved Nanobody-Based CAR-T Cells in KMT2A/MLL1-Rearranged B-ALL., PMID:33727310
Myeloid-like γδ T cell subset in the immune response to an experimental Rift Valley fever vaccine in sheep., PMID:33454621
The emerging roles of semaphorin4D/CD100 in immunological diseases., PMID:33258873
Semaphorin 4D Induces an Imbalance of Th17/Treg Cells by Activating the Aryl Hydrocarbon Receptor in Ankylosing Spondylitis., PMID:33013906
Efficient Expansion of Human Granzyme B-Expressing B Cells with Potent Regulatory Properties., PMID:32948686
CD40 and CD72 expression and prognostic values among children with systemic lupus erythematosus: a case-control study., PMID:32700598
Increased levels of inflammatory markers in the subscapularis tendon and joint capsule in patients with subacromial impingement., PMID:32356046
A regulatory role for CD72 expression on B cells and increased soluble CD72 in primary Sjogren's syndrome., PMID:32306893
Insufficient CD100 shedding contributes to suppression of CD8+ T-cell activity in non-small cell lung cancer., PMID:32149403
[Relapsing-remitting multiple sclerosis: clinical and immunological aspects of the pathology on the example Sema4D and CD72]., PMID:31934990
CD22 and CD72 contribute to the development of scleroderma in a murine model., PMID:31883832
Differential expression of immune-related genes in the bursa of Fabricius of two inbred chicken lines following infection with very virulent infectious bursal disease virus., PMID:31837598
Upregulation of IFN-β induced by Sema4D-dependent partial Erk1/2 inhibition promotes NO production in microglia., PMID:31708102
Receptor Functions of Semaphorin 4D., PMID:31693461
For research use only. Not for human or drug use.
