Catalog No.
YHD47101
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Arg338-Thr446
Predicted molecular weight
14.11 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P21728
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Dopamine D1 receptor, DRD1, D(1A) dopamine receptor
Directing negative emotional states through parallel genetically-distinct basolateral amygdala pathways to ventral striatum subregions., PMID:40514388
Cocaine-induced gene regulation in D1 and D2 neuronal ensembles of the nucleus accumbens., PMID:40506501
Distinct molecular patterns in R6/2 HD mouse brain: Insights from spatiotemporal transcriptomics., PMID:40482637
Impaired insulin receptor function alters psychiatric behaviors without affecting circadian rhythms in a mouse model of Alzheimer's disease., PMID:40443027
Subregion-specific suppression of dopamine D1 receptor expression prevents L-DOPA-induced dyskinesia in a mouse model of Parkinson's disease., PMID:40425071
Abundance of dopamine and its receptors in the brain and adipose tissue following diet-induced obesity or caloric restriction., PMID:40345434
Intermittent fasting produces antidepressant-like effects by modulating dopamine D1 receptors in the medial prefrontal cortex., PMID:40311880
Pharmacological Characterization of Dopamine Receptor DRD1 Variants and Exploration of Their Allosteric Activation., PMID:40311121
Probiotic Bactolac alleviates depression-like behaviors by modulating BDNF, NLRP3 and MC4R levels, reducing neuroinflammation and promoting neural repair in rat model., PMID:40281288
Unique and overlapping mechanisms of valbenazine, deutetrabenazine, and vitamin E for tardive dyskinesia., PMID:40268947
A New Function of the DRD1 Gene: GnRH Secretion Regulation in Sheep Hypothalamic Neurons., PMID:40149425
PACAP induces increased excitability in D1- and D2-expressing nucleus accumbens medium spiny neurons., PMID:40147707
Punishment-Induced Suppression of Methamphetamine Self-Administration Is Accompanied by the Activation of the CPEB4/GLD2 Polyadenylation Complex of the Translational Machinery., PMID:40141377
Dopamine-driven increase in IL-1β in myeloid cells is mediated by differential dopamine receptor expression and exacerbated by HIV., PMID:40122818
Enhancement of D1 dopaminergic responses in aged LRRK2 G2019S knock-in mice., PMID:40120831
Cerebral Blood Flow Changes and Their Spatial Correlations With GABAa and Dopamine-D1 Receptor Explaining Individual Differences in Chronic Insomnia and the Therapeutic Effects of Acupuncture., PMID:40022556
Promising Antidepressant Potential: The Role of Lactobacillus rhamnosus GG in Mental Health and Stress Response., PMID:39962033
Estrogen-related receptor gamma is a regulator of mitochondrial, autophagy, and immediate-early gene programs in spiny projection neurons: Relevance for transcriptional changes in Huntington disease., PMID:39884587
Nitrous oxide exerts rewarding effect via regulating D1 receptor and BDNF pathway in ventral tegmental area-nucleus accumbens dopamine circuit., PMID:39875366
Access to high-fat diet results in increased sensitivity to the psychostimulant effects of MDPV in mice., PMID:39869285
The effects of social loss and isolation on partner odor investigation and dopamine and oxytocin receptor expression in female prairie voles., PMID:39778625
Correlation of repetitive behaviors in deer mice with striatal mRNA expression of endogenous opioids and mu, delta, kappa, and dopamine receptors: A preliminary report., PMID:39756610
Generation and validation of a D1 dopamine receptor Flpo knock-in mouse., PMID:39701542
Prenatal exposure to valproic acid induces sex-specific alterations in rat cortical and hippocampal neuronal structure and function in vitro., PMID:39701172
Developmental and Adult Striatal Patterning of Nociceptin Ligand Marks Striosomal Population With Direct Dopamine Projections., PMID:39656141
Dopamine D1-Like Receptor Stimulation Induces CREB, Arc, and BDNF Dynamic Changes in Differentiated SH-SY5Y Cells., PMID:39601897
The role of the dopamine D1 receptor in anticipatory pleasure and social play., PMID:39566573
Optogenetic Control of Dopamine Receptor 2 Reveals a Novel Aspect of Dopaminergic Neurotransmission in Motor Function., PMID:39562043
Exploring the potential pharmacological mechanism of aripiprazole against hyperprolactinemia based on network pharmacology and molecular docking., PMID:39511179
Behavioral changes and transcriptional regulation of mesolimbic dopaminergic genes in a mouse model of binge eating disorder by diet intermittent access., PMID:39426552
Neurochemical Characterization of Dopaminoceptive Cells in Song Control Nuclei of Canaries and Their Activation During Song Production: A Multiplex Fluorescent In Situ Hybridization Study., PMID:39387367
YAP/TAZ Signaling in the Pathobiology of Pulmonary Fibrosis., PMID:39329703
Network pharmacology and experimental validation reveal the mechanisms of sniffing essential oil of Acori Tatarinowii rhizoma in treating olfactory dysfunction., PMID:39326811
Dopamine receptor autoantibody signaling in infectious sequelae differentiates movement versus neuropsychiatric disorders., PMID:39325550
Dopamine transmission at D1 and D2 receptors in the nucleus accumbens contributes to the expression of incubation of cocaine craving., PMID:39300272
Region-Specific Gene Expression Changes Associated with Oleoylethanolamide-Induced Attenuation of Alcohol Self-Administration., PMID:39201687
Single-cell RNA-seq Reveals the Inhibitory Effect of Methamphetamine on Liver Immunity with the Involvement of Dopamine Receptor D1., PMID:39196711
An RdDM-independent function of Pol V transcripts in gene regulation and plant defence., PMID:39187700
The dopamine analogue CA140 alleviates AD pathology, neuroinflammation, and rescues synaptic/cognitive functions by modulating DRD1 signaling or directly binding to Abeta., PMID:39129007
Contractile effects of stimulation of D1-dopamine receptors in the isolated human atrium., PMID:39102031
Adolescent exposure to bisphenol-a antagonizes androgen regulation of social behavior in male mice., PMID:39097242
Structural basis of psychedelic LSD recognition at dopamine D1 receptor., PMID:39094559
Modulating amacrine cell-derived dopamine signaling promotes optic nerve regeneration and preserves visual function., PMID:39093964
Computational Assessment of the Phytochemicals of Panax ginseng C.A. Meyer Against Dopamine Receptor D1 for Early Huntington's Disease Prophylactics., PMID:39046621
Integrating Molecular Biology and Network Pharmacology to Analyze the Antidepressant Mechanism of Glycyrrhizaglabra., PMID:39041272
Long Mu Qing Xin mixture improves behavioral performance in spontaneously hypertensive rats (SHR/NCrl) by upregulating catecholamine neurotransmitters in prefrontal cortex and striatum via DRD1/cAMP/PKA-CREB signaling pathway., PMID:39027341
Sex differences in sensitivity to fentanyl effects in mice: Behavioral and molecular findings during late adolescence., PMID:39013536
Conditional deletion of the AMPA-GluA1 and NMDA-GluN1 receptor subunit genes in midbrain D1 neurons does not alter cocaine reward in mice., PMID:39002853
Involvement of D1 dopamine receptor in the nucleus of the solitary tract of rats in stress-induced hypertension and exercise., PMID:38973449
Sex and Age Differences in Ontogeny of Alloparenting: A Relation to Forebrain DRD1, DRD2, and HTR2A mRNA Expression?, PMID:38973227
For research use only. Not for human or drug use.
