Catalog No.
YHD43601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser3905-Tyr4031
Predicted molecular weight
16.33 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P20930
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
FLG, Filaggrin
Rab7 inhibitor enhances stem cell differentiation into keratinocyte-like cells with anti-inflammatory properties., PMID:40491919
Revitalising Brewers' Spent Grains and Enriching With Biogenic Compounds Through the Fermentation of Fructophilic Lactic Acid Bacteria and Yeasts., PMID:40491241
Polynucleotides Enhance Skin Barrier Function and Reduce Inflammation in a 2,4-Dinitrochlorobenzene-Induced Mouse Model of Atopic Dermatitis., PMID:40484710
LncRNA FLG-AS1 inhibits esophageal squamous cell carcinoma by regulating the miR-23a-3p/HOXD10 axis., PMID:40462237
A Novel Antiviral Therapeutic Platform: Anchoring IFN-β to the Surface of Infectious Virions Equips Interferon-Evasive Virions with Potent Antiviral Activity., PMID:40431708
Glycine soja Leaf and Stem Extract Ameliorates Atopic Dermatitis-like Skin Inflammation by Inhibiting JAK/STAT Signaling., PMID:40429704
FGF-21 fusion proteins ameliorate atopic dermatitis by inhibiting the TLR/TSLP signaling pathway: Anti-inflammatory and skin barrier repair effects., PMID:40424659
The alleviating effect of Bai-Ju essence on atopic dermatitis through anti-inflammatory and skin barrier repair mechanisms., PMID:40394445
Anti-inflammatory and barrier repair mechanisms of active components in Daemonorops draco Bl. for UVB-induced skin damage., PMID:40382359
Synergistic Enhancement of Compromised Skin Radiance: A Clinical Investigation of Prinsepia utilis Royle Polysaccharides and Nonapeptide Co-Application., PMID:40367144
Blocking of IL-4/IL-13 Signalling With Dupilumab Results in Restoration of Serum and Cutaneous Abnormalities in Netherton Syndrome., PMID:40344324
Analysis of Rare Coding Variants in 470,000 UK Biobank Participants Reveals Genetic Associations With Childhood Asthma Predisposition., PMID:40342259
An in silico approach deciphering the commensal dynamics in the cutaneous milieu., PMID:40335508
Synergistic effects of oral milk ceramide-collagen peptides mixtures in preventing UV-induced inflammation and photoaging through TGF-β and NF-κB/MAPK signaling pathways in UV-exposed hairless mice., PMID:40319715
Assessment of aqueous graphene as a cancer therapeutics delivery system., PMID:40316695
Identification and Biological Characteristics of Rare Pathogen Comamonas kerstersii in the First Case of Gallbladder Puncture Fluid., PMID:40314779
HSPA2 influences the differentiation and production of immunomodulatory mediators in human immortalized epidermal keratinocyte lines., PMID:40287440
Novel Filaggrin Variants Are Associated with Ichthyosis Vulgaris in Mexicans., PMID:40282340
Study on Moisturizing Effect of Dendrobium officinale, Sparassis crispa, and Their Compound Extracts., PMID:40247751
Skin Protection Effects of Lactobacillus paragasseri HN910 Lysate and the Role of Alanine., PMID:40244537
Investigating the Therapeutic Potential of Sericin Nanofibers and Rice-Encapsulated Nanosericin for Psoriasis: Mechanistic Insights from a 3D Skin Model., PMID:40225220
ART26.12, an FABP5 Inhibitor, Shows Efficacy in Preclinical Psoriasis Models., PMID:40210114
Tirzepatide did not impact metabolic adaptation in people with obesity, but increased fat oxidation., PMID:40203836
Atopic March in a Case of Filaggrin Gene Mutation., PMID:40197870
Effects of a Moisturizer Containing Colloidal Oatmeal and Filaggrin Technology on Staphylococcus Species In Vitro., PMID:40196947
Role of DNA Methylation in the Pathogenesis of Skin Disorders: Mechanisms, Inhibitors of Methylation-Related Enzyme, and Molecular Docking Studies., PMID:40182929
The role of LINC00114 in atopic dermatitis: modulating inflammation and epidermal barrier dysfunction., PMID:40167775
Determination via an Integration Strategy of the Potential Dermal ECM Reconstruction Mechanism by Which the WAW Formula Alleviates Skin Aging., PMID:40160145
Defining the Blood Cytokine Profile in Asthma to Understand Asthma Heterogeneity., PMID:40105091
[Joss-stick moxibustion reduces inflammatory response of acute eczema by inhibiting IL-6/STAT3 signaling, and balancing Th17/Treg to normalize filaggrin and Caspase-14 levels in rats]., PMID:40103381
Time-of-day dependent promotion of keratinocyte differentiation by Cinnamomum cassia bark extract through the p38 MAPK Pathway., PMID:40100929
Regulation of keratinocyte proliferation and differentiation by secoiridoid oleacein in monoculture and fibroblast co-culture models., PMID:40088777
Effects of natural killer cell‑conditioned medium on UVB‑induced photoaging in human keratinocytes and a human reconstructed skin model., PMID:40084708
Ameliorative Effects of Escin on Inflammation via Glucocorticoid Receptor (GR) in Atopic Dermatitis (AD) Mouse Model., PMID:40081901
Comparing UV and Diesel Cutaneous Damage and Evaluating the Protective Role of a Topical Antioxidant Mixture Containing Vitamin C, E and Ferulic Acid., PMID:40062421
Anti photoaging mechanism of a novel recombinant human fibronectin peptide (rhFNP) derived from the extracellular matrix., PMID:40061928
Efficacy of [68Ga]Ga-FAPI-PET as a non-invasive evaluation method of liver fibrosis., PMID:40048016
Effects on the Skin Microbiome by a Moisturizer Formulated for Eczema-Prone and Sensitive Skin., PMID:40043265
A Deep Dive Into the Potential Antiaging Effects of Colla Corii Asini on the Skin: A Comparative Study., PMID:40012471
A role for Arginase in skin epithelial differentiation and anti-microbial peptide production., PMID:39950979
Poly-γ-Glutamic Acid from a Novel Bacillus subtilis Strain: Strengthening the Skin Barrier and Improving Moisture Retention in Keratinocytes and a Reconstructed Skin Model., PMID:39940752
Effect of low humidity on the barrier functions of keratinocytes in a reconstructed human epidermal model., PMID:39935117
Filaggrinopathies-FLG/FLG2: Diagnostic Complexities and Immunotherapy., PMID:39927906
Myricetin enhances keratinocytes differentiation via TRPV4 channel activation in mouse primary keratinocytes., PMID:39907058
Computational network analysis of two popular skin cancers provides insights into the molecular mechanisms and reveals common therapeutic targets., PMID:39866430
Restorative effects of camellia oil on the skin-barrier function in a model of DNCB-induced atopic dermatitis., PMID:39836107
Highly accurate, noninvasive early identification of infants with a filaggrin loss-of-function mutation by in vivo Raman spectroscopy, followed from birth to 12 months., PMID:39826898
Differential Expression of Proteins Involved in Skin Barrier Maintenance and Vitamin D Metabolism in Atopic Dermatitis: A Cross-Sectional, Exploratory Study., PMID:39796069
Do continuous glucose monitoring (CGM) metrics predict macrovascular and microvascular complications in diabetes? The FACULTY protocol of a retrospective real-world cohort study., PMID:39779259
Aging Skin: A Dermatitis To Which All Flesh Is Heir?, PMID:39777799
For research use only. Not for human or drug use.
