Catalog No.
YHD42201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Pro22-Leu199
Predicted molecular weight
21.42 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P20809
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Adipogenesis inhibitory factor, AGIF, IL11, IL-11, Interleukin-11, Oprelvekin
Combined Oral Contraceptives Modulate Apoptosis via IL-11/PI3K/AKT Pathway in Rat With Premature Ovarian Insufficiency., PMID:40485524
Genetic Insights Into Craniosynostosis: Identification of Novel IL11RA Variants in Chinese Pediatric Patients., PMID:40353334
Shenge powder inhibits myocardial fibrosis in rats with post-myocardial infarction heart failure through LOXL2/TGF-β1/IL-11 signaling pathway., PMID:40342293
"Maladaptive stress-coping behavior in CX3CR1-deficient mice: Impact of adolescent stress and alcohol exposure on neuroimmune responses and inflammation"., PMID:40339639
Inhalable myofibroblast targeting nanoparticles for synergistic treatment of pulmonary fibrosis., PMID:40305619
COVID-19 mRNA-1273 vaccination induced mast cell activation with strongly elevated Th2 cytokines in a systemic mastocytosis patient., PMID:40299000
Therapeutic effect of nintedanib in orbital fibroblasts in patients with Graves' orbitopathy., PMID:40289264
Toxic effects and transcriptome analysis of the early life stages of Larimichthys crocea exposed to the bloom-forming dinoflagellate Alexandrium tamarense., PMID:40252594
Development of a Long-Acting Interleukin-11 Antagonist for the Treatment of Renal Fibrosis., PMID:40198895
Sodium propionate protects against bronchopulmonary dysplasia by inhibiting IL-17-mediated apoptosis of alveolar epithelial cells., PMID:40188136
The signature based on interleukin family and receptors identified IL19 and IL20RA in promoting nephroblastoma progression through STAT3 pathway., PMID:40185911
Biomarkers of the Complement System in Cancer., PMID:40152065
IL-11 promotes Ang II-induced autophagy inhibition and mitochondrial dysfunction in atrial fibroblasts., PMID:40092733
Interleukin-11 expressed in the polyp-enriched fibroblast subset is a potential therapeutic target in Peutz-Jeghers syndrome., PMID:40070038
Exploring immunological and molecular mechanisms involved in obsessive-compulsive disorder with comorbid neurodevelopmental disorders., PMID:40036942
PDK2-enhanced glycolysis aggravates fibrosis via IL11 signaling pathway in Graves' orbitopathy., PMID:40018034
Biofunctionalization of Collagen Barrier Membranes with Bone-Conditioned Medium, as a Natural Source of Growth Factors, Enhances Osteoblastic Cell Behavior., PMID:40004074
IL-11 regulates the biosynthesis of PGE2 through JAK1/STAT3 signaling pathway in bovine granulosa cells., PMID:39986217
Spatial proteomics identifies a CRTC-dependent viral signaling pathway that stimulates production of interleukin-11., PMID:39921859
Comparative analysis of salivary cytokine profiles and oral microbial composition in caries-active and caries-free children., PMID:39921084
Site-specific immunoglobulin G N-glycosylation is associated with gastric cancer progression., PMID:39920693
Edaravone dexborneol alleviates pericyte-mediated fibrosis depositing extracellular matrix through TGF-β1/IL-11 in cerebral small vessel disease., PMID:39910578
TME-responsive nanocomposite hydrogel with targeted capacity for enhanced synergistic chemoimmunotherapy of MYC-amplified osteosarcoma., PMID:39897587
Potential benefits of ketone therapy as a novel immunometabolic treatment for schizophrenia., PMID:39892306
Transforming growth factor beta induces interleukin-11 expression in osteoarthritis., PMID:39879889
Exploring the therapeutic effect of human recombinant IL11 on lesioned OA human osteochondral explants., PMID:39856704
Long-term increase in soluble interleukin-6 receptor levels in convalescents after mild COVID-19 infection., PMID:39835136
Role of Adenosine A1 Receptor in Sleep Deprivation-Induced Neuroinflammation: Insights on Rapid Eye Movement Sleep and Fear Extinction Memory Recall in Rats., PMID:39830563
Sinensetin attenuates LPS-induced acute pulmonary inflammation in mice and RAW264.7 cells by modulating NF-κB p65-mediated immune resistance and STAT3-mediated tissue resilience., PMID:39827664
Decreased expression of LEF1 caused defective decidualization by inhibiting IL-11 expression in patients with adenomyosis., PMID:39794729
Inhalable siRNA Targeting IL-11 Nanoparticles Significantly Inhibit Bleomycin-Induced Pulmonary Fibrosis., PMID:39791575
Pharmacokinetic and Metabolomic Studies with BBT-059 in Nonhuman Primates Exposed to Total-Body Gamma Radiation., PMID:39786949
Bone Marrow Mesenchymal Stem Cells Ameliorate Diabetes and Diabetic Renal Fibrosis by Modulating the Inflammatory Factor IL-11., PMID:39757600
Single cell and spatial analysis of immune-hot and immune-cold tumours identifies fibroblast subtypes associated with distinct immunological niches and positive immunotherapy response., PMID:39757146
De novo discovery of cyclic peptide inhibitors of IL-11 signaling., PMID:39756345
Didecyldimethylammonium chloride-induced lung fibrosis may be associated with phospholipidosis., PMID:39710153
Potential Biomarkers in Myocardial Fibrosis: A Bioinformatic Analysis., PMID:39699450
Higher Intraocular Levels of Inflammatory Factors are Related to Retinal Vascular and Neurodegeneration in Myopic Retinopathy., PMID:39677296
More and more pleiotropy within the IL-6 family of cytokines., PMID:39673075
Study of Neuroinflammation in the Rat Hippocampus during Ethanol Exposure and Pharmacological Correction with Azithromycin: New Data and Future Perspectives., PMID:39647820
Prevent and Reverse Metabolic Dysfunction-Associated Steatohepatitis and Hepatic Fibrosis via mRNA-Mediated Liver-Specific Antibody Therapy., PMID:39639502
Breast cancer stem cell-derived exosomal lnc-PDGFD induces fibroblast-niche formation and promotes lung metastasis., PMID:39633064
The dichotomic role of cytokines in aging., PMID:39621124
Integrated Transcriptome Profiling and Pan-Cancer Analyses Reveal Oncogenic Networks and Tumor-Immune Modulatory Roles for FABP7 in Brain Cancers., PMID:39596296
Ershen Zhenwu Decoction suppresses myocardial fibrosis of chronic heart failure with heart-kidney Yang deficiency by down-regulating the Ras Homolog Gene Family Member A/Rho-Associated Coiled-Coil Kinases signaling pathway., PMID:39580131
Expression profiling of antimicrobial peptides and immune-related genes in Nile tilapia following Pseudomonas putida infection and nano-titanium dioxide gel exposure., PMID:39577786
Effects of intranasal administration with a symbiotic strain of Bacillus velezensis NSV2 on nasal cavity mucosal barrier in lambs., PMID:39565462
Interleukin-11 signaling plays limited roles for liver fibrosis in a mouse model of metabolic dysfunction-associated steatohepatitis., PMID:39536410
The m6A and immune regulatory gene signature predicts the prognosis and correlates with immune infiltration of head and neck squamous cell carcinoma., PMID:39524706
Single-cell landscape identified SERPINB9 as a key player contributing to stemness and metastasis in non-seminomas., PMID:39528470
For research use only. Not for human or drug use.
