Catalog No.
YHD36401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Phe41-Gln117
Predicted molecular weight
10.46 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P19957
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
PI3, Elastase-specific inhibitor, WAP3, Elafin, Protease inhibitor WAP3, Peptidase inhibitor 3, PI-3, Skin-derived antileukoproteinase, SKALP, ESI, WFDC14, WAP four-disulfide core domain protein 14
In Silico Exploration of Ayurvedic Extract for Targeting Diabetes Mellitus and Non-alcoholic Fatty Liver Disease Via GPR120 and GPR40., PMID:40511827
Knockdown of MACC1 expression attenuates colorectal cancer cell glucose metabolism by suppressing GLUT4 membrane translocation., PMID:40501119
Noninvasive markers for warning premature ovarian insufficiency: a Mendelian randomisation study., PMID:40495196
TSPAN31 Activates EMT Through the PI3 K/AKT Signaling Pathway to Promote Glioma Progression., PMID:40488790
S100 A16 promotes the progression of osteosarcoma by activating the PI3 K/AKT signaling pathway through ANXA2., PMID:40481236
PIKI-1, a class II phosphatidylinositol 3-kinase, functions in endocytic trafficking., PMID:40475523
Integrated multi-omics analysis identifies TLR4-mediated mechanisms in ATBC-induced ovarian dysfunction and female infertility: A network toxicology, transcriptomic, and Mendelian randomization study., PMID:40462131
Phosphoinositides: Nanoscale Effects on Neuronal Membranes., PMID:40437879
Screening of Leptin-LepR modulators using molecular docking and binding assay., PMID:40400663
Study on the molecular mechanism of UBA52 and BARD1 regulating hepatocellular carcinoma through the PI3 K/AKT signaling pathway., PMID:40397202
Galvanotactic directionality of cell groups depends on group size., PMID:40392857
Case Report: Activated PI3-kinase-δ syndrome and ovarian malignancies: a case series from the European ESID-APDS registry., PMID:40370432
Novel application of CHUANG BI FU biologic protein sponge in promoting peripheral nerve injury repair by regulating vascular regeneration., PMID:40369654
PI3-kinase has multiple functions in asexual blood stages of Plasmodium falciparum., PMID:40369090
Circ_0081343 promotes autophagy and alleviates pyroptosis via PI3 K/AKT/HIF-1α axis in hypoxia-induced fetal growth restriction of mice., PMID:40353255
Age-linked DNA methylation and gene expression patterns in parameningeal head and neck alveolar rhabdomyosarcoma reveal CDK9 as a promising therapeutic target., PMID:40350107
Extracellular regucalcin reveals anti-cancer activity by suppressing cell growth and metastatic activity by blocking EGF signaling pathway in human glioblastoma cells in vitro., PMID:40318797
Double Swords in One: Novel Selective PI3K/110β PROTAC Degraders for the Treatment of Multidrug-Resistant Cancer by Activating ERS and Inhibiting P-gp., PMID:40294240
Pharmacological inhibition of PLC and PKC triggers epileptiform activity in hippocampal neurons., PMID:40288030
Isoleucine Side Chains as Reporters of Conformational Freedom in Protein Folding Studied by DNP-Enhanced NMR., PMID:40285725
Dissecting the genetic association between abnormal sperm parameters and depression: a transcriptome-wide analysis of 157 participants., PMID:40263245
Discovery of novel PI3KC2γ inhibitors with high potency, selectivity, and favorable pharmacokinetics for glycogen metabolism regulation., PMID:40262302
Emerging oral Treponema membrane proteins disorder neutrophil phosphoinositide signaling via phosphatidylinositol-4-phosphate 5-kinase., PMID:40248422
Study on the regulatory mechanism of luteolin inhibiting WDR72 on the proliferation and metastasis of non small cell lung cancer., PMID:40216870
LINC01559: roles, mechanisms, and clinical implications in human cancers., PMID:40205068
TPCs: FROM PLANT TO HUMAN., PMID:40197126
In vivo validation of the palmitoylation cycle as a therapeutic target in NRAS-mutant cancer., PMID:40166265
Dual Targeting of Pim and PI3 Kinases in Mature T-Cell Lymphoma., PMID:40165380
PIP2-mediated oligomerization of the endosomal sodium/proton exchanger NHE9., PMID:40155618
An advanced toolset to manipulate and monitor subcellular phosphatidylinositol 3,5-bisphosphate., PMID:40138452
Sorting nexin 10 regulates lysosomal ionic homeostasis via ClC-7 by controlling PI(3,5)P2., PMID:40138451
PI3Kβ functions as a protein kinase to promote cellular protein O-GlcNAcylation and acetyl-CoA production for tumor growth., PMID:40132583
Lysosomal PIP3 revealed by genetically encoded lipid biosensors., PMID:40127277
PI(3,4,5)P3-mediated Cdc42 activation regulates macrophage podosome assembly., PMID:40126693
miR-335-5p Inhibits EMT and PI3K/AKT Pathways via MARCH8., PMID:40123623
Membrane composition and curvature in SNX9-mediated actin polymerization., PMID:40105919
Exploring the bioactive properties and mechanism of Aegle marmelos in the treatment of inflammatory bowel disease through network pharmacology and a molecular docking approach., PMID:40092097
Akt inhibition is effective against PTEN-deleted, chemoirradiation-resistant glioblastoma stem cells., PMID:40078116
Leptin as a potential neuroprotective target in Parkinson's Disease: Exploring its role in Neuroinflammation, oxidative Stress, and dopaminergic neurodegeneration., PMID:40064367
L1CAM mimetic compound duloxetine improves cognitive impairment in 5xFAD mice and protects Aβ1-42-damaged HT22 cells., PMID:40057157
IFITM2 Modulates Endocytosis Maintaining Neural Stem Cells in Developing Neocortex., PMID:40052215
Network pharmacology exploring the mechanistic role of indirubin phytoconstituent from Indigo naturalis targeting GSK-3β in Alzheimer's disease., PMID:40035614
Uncovering the potential mechanism and bioactive compounds of Salviae Miltiorrhizae Radix et Rhizoma in attenuating diabetic retinopathy., PMID:39986223
Class I PI3Ks activate stretch-induced autophagy in trabecular meshwork cells., PMID:39985671
In silico characterization of the gating and selectivity mechanism of the human TPC2 cation channel., PMID:39982432
Individual mHLA-DR trajectories in the ICU as predictors of early infections following liver transplantation: a prospective observational study., PMID:39966934
Transcriptional Regulation of NUPR1 by MYH11 Activates PI3 K/AKT and Promotes Bladder Cancer Progression Through Ferroptosis and M2 Polarization of Macrophages., PMID:39962891
Identification of novel biomarkers associated with immune infiltration in major depression disorder and atopic dermatitis., PMID:39953304
Targeting Runx1 in Pathological Retinal Angiogenesis: A Potential Therapeutic Approach., PMID:39946136
Single-molecule lipid biosensors mitigate inhibition of endogenous effector proteins., PMID:39932556
For research use only. Not for human or drug use.
