Catalog No.
RHD13601
Species reactivity
Human
Host species
Mouse
Isotype
IgG2b
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400
Target
TCF-4, SL3-3 enhancer factor 2, Immunoglobulin transcription factor 2, ITF2, SEF-2, SEF2, bHLHb19, ITF-2, TCF4, Transcription factor 4, BHLHB19, Class B basic helix-loop-helix protein 19
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P15884
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R3E16
Neurogranin facilitates maintaining the immunosuppressive state of hepatocellular carcinoma by promoting TGF-β1 secretion., PMID:40316076
KIF26B promotes bladder cancer progression via activating Wnt/β-catenin signaling in a TRAF2-dependent pathway., PMID:40253697
DNAJB1-PKAc Kinase Is Expressed in Young Patients with Pediatric Liver Cancers and Enhances Carcinogenic Pathways., PMID:39796711
CD84 as a therapeutic target for breaking immune tolerance in triple-negative breast cancer., PMID:39466774
Genomic determinants of antibody response to a typhoid vaccine in Indian recipients., PMID:38444027
In vitro study of miRNA-369-3p targeting TCF4 regulating the malignant biological behavior of colon cancer cells., PMID:37969834
Blastic Plasmacytoid Dendritic Cell Neoplasm., PMID:37156483
The chromatin remodeler CHD6 promotes colorectal cancer development by regulating TMEM65-mediated mitochondrial dynamics via EGF and Wnt signaling., PMID:36473865
A p38α-BLIMP1 signalling pathway is essential for plasma cell differentiation., PMID:36443297
Interaction of lncRNA MIR100HG with hnRNPA2B1 facilitates m6A-dependent stabilization of TCF7L2 mRNA and colorectal cancer progression., PMID:35279145
NOX4 stimulates ANF secretion via activation of the Sirt1/Nrf2/ATF3/4 axis in hypoxic beating rat atria., PMID:35029280
Anti-SARS-CoV-2 and Autoantibody Profiles in the Cerebrospinal Fluid of 3 Teenaged Patients With COVID-19 and Subacute Neuropsychiatric Symptoms., PMID:34694339
Ginsenoside Rb1 Lessens Gastric Precancerous Lesions by Interfering With β-Catenin/TCF4 Interaction., PMID:34594214
RANKL immunisation inhibits prostate cancer metastasis by modulating EMT through a RANKL-dependent pathway., PMID:34108600
TSPAN1 promotes autophagy flux and mediates cooperation between WNT-CTNNB1 signaling and autophagy via the MIR454-FAM83A-TSPAN1 axis in pancreatic cancer., PMID:32972302
Dendritic cells' characteristics in patients with treated systemic lupus erythematosus., PMID:32730703
Hepcidin deficiency causes bone loss through interfering with the canonical Wnt/β-catenin pathway via Forkhead box O3a., PMID:32514392
The Wnt3a/β-catenin/TCF7L2 signaling axis reduces the sensitivity of HER2-positive epithelial ovarian cancer to trastuzumab., PMID:32248976
Assessment of anti-cancer effects of koenimbine on colon cancer cells., PMID:32116245
The let-7 family of microRNAs suppresses immune evasion in head and neck squamous cell carcinoma by promoting PD-L1 degradation., PMID:31881947
Wnt/β-Catenin Pathway-Regulated Fibromodulin Expression Is Crucial for Breast Cancer Metastasis and Inhibited by Aspirin., PMID:31824307
SOX21 Ensures Rostral Forebrain Identity by Suppression of WNT8B during Neural Regionalization of Human Embryonic Stem Cells., PMID:31761677
Quantitative Studies of Muscleblind Proteins and Their Interaction With TCF4 RNA Foci Support Involvement in the Mechanism of Fuchs' Dystrophy., PMID:31560764
Immunohistochemistry Innovations for Diagnosis and Tissue-Based Biomarker Detection., PMID:31338668
Anti-TSNARE1 IgG plasma levels differ by sex in patients with schizophrenia in a Chinese population., PMID:31336035
Targetable genetic alterations of TCF4 (E2-2) drive immunoglobulin expression in diffuse large B cell lymphoma., PMID:31217338
The Influence of Type 2 Diabetes-Associated Factors on Type 1 Diabetes., PMID:31167894
Blastic Plasmacytoid Dendritic Cell Neoplasm: State of the Art and Prospects., PMID:31035408
Expression and clinical significance of transcription factor 4 (TCF4) in epithelial ovarian cancer., PMID:30614797
Transcription Factor 7-Like 2 (TCF7L2) Gene Polymorphism and Progression From Single to Multiple Autoantibody Positivity in Individuals at Risk for Type 1 Diabetes., PMID:30275285
Generation of novel Id2 and E2-2, E2A and HEB antibodies reveals novel Id2 binding partners and species-specific expression of E-proteins in NK cells., PMID:30144957
Repeat-Associated Non-ATG (RAN) Translation in Fuchs' Endothelial Corneal Dystrophy., PMID:29677349
Sclerostin vaccination mitigates estrogen deficiency induction of bone mass loss and microstructure deterioration., PMID:29653294
Study of Novel Autoantibodies in Schizophrenia., PMID:29373732
Linking FOXO3, NCOA3, and TCF7L2 to Ras pathway phenotypes through a genome-wide forward genetic screen in human colorectal cancer cells., PMID:29301589
Osteopontin production by TM4SF4 signaling drives a positive feedback autocrine loop with the STAT3 pathway to maintain cancer stem cell-like properties in lung cancer cells., PMID:29254164
Targeting the Wnt Pathway and Cancer Stem Cells with Anti-progastrin Humanized Antibodies as a Potential Treatment for K-RAS-Mutated Colorectal Cancer., PMID:28600477
Environmental Enrichment Induces Pericyte and IgA-Dependent Wound Repair and Lifespan Extension in a Colon Tumor Model., PMID:28445727
Identification of FERM domain-containing protein 5 as a novel target of β-catenin/TCF7L2 complex., PMID:28117551
T-cell factor-4 and MHC upregulation in pigs receiving a live attenuated classical swine fever virus (CSFV) vaccine strain with interferon-gamma adjuvant., PMID:27687943
[Application of Unfolded Protein Response for Production of Biologics]., PMID:27252063
Dynamic changes in Id3 and E-protein activity orchestrate germinal center and plasma cell development., PMID:27217539
Dissecting heterogeneity in paediatric Type 1 diabetes: association of TCF7L2 rs7903146 TT and low-risk human leukocyte antigen (HLA) genotypes., PMID:27027642
APR-246/PRIMA-1Met Inhibits and Reverses Squamous Metaplasia in Human Conjunctival Epithelium., PMID:26868746
β-catenin is regulated by USP9x and mediates resistance to TRAIL-induced apoptosis in breast cancer., PMID:26717875
Plasmacytoid dendritic cells are dispensable for noninfectious intestinal IgA responses in vivo., PMID:26518732
Genome-wide ChIP-seq analysis of TCF4 binding regions in colorectal cancer cells., PMID:25550940
SOX10, a novel HMG-box-containing tumor suppressor, inhibits growth and metastasis of digestive cancers by suppressing the Wnt/β-catenin pathway., PMID:25301735
Overlap of genetic susceptibility to type 1 diabetes, type 2 diabetes, and latent autoimmune diabetes in adults., PMID:25189437
Genetic evidence for the role of plasmacytoid dendritic cells in systemic lupus erythematosus., PMID:25180061
For research use only. Not for human or drug use.
