Catalog No.
YHD36201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Lys355-Val526
Predicted molecular weight
22.01 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P19878
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Neutrophil NADPH oxidase factor 2, NOXA2, p67-phox, NADPH oxidase activator 2, 67 kDa neutrophil oxidase factor, Neutrophil cytosol factor 2, NCF-2, NCF2, P67PHOX
Single-cell and spatial transcriptomics reveal the pathogenesis of chronic granulomatous disease in a natural model., PMID:40272982
Unraveling the Hsp70-ROS-autophagy axis in pentachlorophenol-challenged lung and liver epithelial cells., PMID:40189663
Analysis of the molecular mechanisms of ulcerative colitis and atherosclerosis by microarray data., PMID:40155679
SRC involves in lysosomal function and regulates ferroptosis in polycystic ovary syndrome., PMID:40045372
Ecdysterone Alleviates Atherosclerosis by Inhibiting NCF2 and Inhibiting Ferroptosis Mediated by the PI3K/Akt/Nrf2 Pathway., PMID:40045169
S100A8 induces cyclophosphamide-induced alopecia via NCF2/NOX2-mediated ferroptosis., PMID:39947495
Characterization of Ferroptosis-Related Genes in Aplastic Anaemia: An Integrated Analysis of Bulk and Single-Cell RNA Sequencing Data., PMID:39938486
Identification of key genes associated with oxidative stress in ischemic stroke via bioinformatics integrated analysis., PMID:39806309
Elucidating the molecular association and potential mechanisms between psoriasis and atrial fibrillation through biomarker and immune infiltration analysis., PMID:39776247
An Integrative analysis of single-cell RNA-seq, transcriptome and Mendelian randomization for the Identification and validation of NAD+ Metabolism-Related biomarkers in ulcerative colitis., PMID:39647286
NADPH oxidase expression profile and PBMC immunophenotypic changes in anti-TNF-treated rheumatoid arthritis patients., PMID:39643026
Two distinct clinical progressions of P67phox-deficient CGD, both commencing with cervical lymphadenitis., PMID:39501406
Downregulation of ferroptosis-related ATF3 alleviates lupus nephritis progression., PMID:39427833
Revealing disease subtypes and heterogeneity in common variable immunodeficiency through transcriptomic analysis., PMID:39396099
Comprehensive multi-omics analysis of the prognostic value and immune signature of NCF2 in pan-cancer and its relationship with acute myeloid leukemia., PMID:39393272
Key Disease-Related Genes and Immune Cell Infiltration Landscape in Inflammatory Bowel Disease: A Bioinformatics Investigation., PMID:39273699
MYO5B and the Polygenic Landscape of Very Early-Onset Inflammatory Bowel Disease in an Ethnically Diverse Population., PMID:39096520
Investigating the Role of Inflammatory Response in Polycystic Ovary Syndrome Using Integrated RNA-Seq Analysis., PMID:39051051
Investigating the molecular mechanisms underlying the co-occurrence of Parkinson's disease and inflammatory bowel disease through the integration of multiple datasets., PMID:39043798
In vivo vitamin D target genes interconnect key signaling pathways of innate immunity., PMID:39042613
Targeted serum proteome profiling reveals nicotinamide adenine dinucleotide phosphate (NADPH)-related biomarkers to discriminate linear IgA bullous disorder from dermatitis herpetiformis., PMID:38908771
NCF4 attenuates colorectal cancer progression by modulating inflammasome activation and immune surveillance., PMID:38886341
Systems genetics uncover new loci containing functional gene candidates in Mycobacterium tuberculosis-infected Diversity Outbred mice., PMID:38861581
Identification of co-expressed central genes and transcription factors in acute myocardial infarction and diabetic nephropathy., PMID:38764052
Immune Thrombocytopenic Purpura (ITP) and Chorioretinopathy in Chronic Granulomatous Disease: A Case Report., PMID:38760640
Clinical and molecular significance of flow cytometric analysis for reactive oxygen species production and residual p67phox expression in p67phox-deficient chronic granulomatous disease., PMID:38654426
Multiplex proteomics identifies inflammation-related plasma biomarkers for aging and cardio-metabolic disorders., PMID:38649851
[Correlation study of NCF2 in chronic rhinosinusitis with nasal polyps]., PMID:38563173
Novel biomarkers related to oxidative stress and immunity in chronic kidney disease., PMID:38515668
NADPH oxidase exerts a B cell-intrinsic contribution to lupus risk by modulating endosomal TLR signals., PMID:38442270
Bioinformatics Analysis Identifies PLA2G7 as a Key Antigen-Presenting Prognostic Related Gene Promoting Hepatocellular Carcinoma through the STAT1/PD-L1 Axis., PMID:38287833
Myeloid cell MHC I expression drives CD8+ T cell activation in nonalcoholic steatohepatitis., PMID:38274832
Systems genetics uncover new loci containing functional gene candidates in Mycobacterium tuberculosis-infected Diversity Outbred mice., PMID:38187647
Leukocyte differential gene expression prognostic value for high versus low seizure frequency in temporal lobe epilepsy., PMID:38166692
Duplication of Exons 8-9 in NCF2 Leading to Incomplete Clinical Penetrance in Chronic Granulomatous Disease., PMID:38129542
Genetic characteristics of common variable immunodeficiency patients with autoimmunity., PMID:38028622
MTDH enhances radiosensitivity of head and neck squamous cell carcinoma by promoting ferroptosis based on a prognostic signature., PMID:37981296
Mettl3/Ythdf2 regulate macrophage inflammation and ROS generation by controlling Pyk2 mRNA stability., PMID:37952687
Bioinformatics analyses of potentially common pathogenic networks for primary Sjögren's syndrome complicated with acute myocardial infarction., PMID:37935719
Integrating plasma proteomes with genome-wide association data for causal protein identification in multiple myeloma., PMID:37775746
Identification and validation of ferroptosis-related biomarkers in steroid-induced osteonecrosis of the femoral head., PMID:37690237
M6A-mediated-upregulation of lncRNA BLACAT3 promotes bladder cancer angiogenesis and hematogenous metastasis through YBX3 nuclear shuttling and enhancing NCF2 transcription., PMID:37612524
Identification of novel potential genes in testicular germ cell tumors: A transcriptome analysis., PMID:37599523
Mechanistic insights into super-enhancer-driven genes as prognostic signatures in patients with glioblastoma., PMID:37432454
[Bacillus Calmette-Guérin infection and chronic granulomatous disease due to new pathogenic variants in the NCF2 gene in the Mayan ethnic group. Report of two cases.]., PMID:37218049
Transcriptomic analysis reveals shared gene signatures and molecular mechanisms between obesity and periodontitis., PMID:37063877
Bioinformatics analysis of potential key ferroptosis-related genes involved in tubulointerstitial injury in patients with diabetic nephropathy., PMID:37038746
Exploring a shared genetic signature and immune infiltration between spontaneous intracerebral hemorrhage and Helicobacter pylori infection., PMID:36914055
Role of NCF2 as a potential prognostic factor and immune infiltration indicator in hepatocellular carcinoma., PMID:36680322
Identification and Verification of Biomarkers and Immune Infiltration in Obesity-Related Atrial Fibrillation., PMID:36671813
For research use only. Not for human or drug use.
