Catalog No.
YHD35701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gly506-Leu818
Predicted molecular weight
37.01 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P19827
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Inter-alpha-trypsin inhibitor complex component III, ITI heavy chain H1, SHAP, Inter-alpha-inhibitor heavy chain 1, Serum-derived hyaluronan-associated protein, ITI-HC1, IGHEP1, ITIH1, Inter-alpha-trypsin inhibitor heavy chain H1
Identifying novel protein biomarkers with cross-psychiatric disorders effects and potential intervention targets: Evidence from proteomic-Mendelian randomization., PMID:40334965
Mendelian Randomization Analysis of the Possible Causal Relationships Between Neurodevelopment-Related Proteins and Bipolar Disorder., PMID:40123161
Novel Biomarkers for Screening Retinal Detachment Associated with Choroidal Detachment Using DIA-MS-Based Proteomics., PMID:40012137
PSMB4: a potential biomarker and therapeutic target for depression, perspective from integration analysis of depression GWAS data and human plasma proteome., PMID:39979251
The structural organisation of pentraxin-3 and its interactions with heavy chains of inter-α-inhibitor regulate crosslinking of the hyaluronan matrix., PMID:39814214
Identifying therapeutic targets for kidney stone disease through proteome-wide Mendelian randomization and colocalization analysis., PMID:39585470
Exploring susceptibility and therapeutic targets for kidney stones through proteome-wide Mendelian randomization., PMID:39530187
Identification of novel drug targets for osteoarthritis by integrating genetics and proteomes from blood., PMID:39261869
Proteome-wide mendelian randomization identifies therapeutic targets for nephrolithiasis., PMID:39237840
m6A-Dependent ITIH1 Regulated by TGF-β Acts as a Target for Hepatocellular Carcinoma Progression., PMID:39234824
Association between genetically plasma proteins and osteonecrosis: a proteome-wide Mendelian randomization analysis., PMID:39119575
ITIH1 suppresses carcinogenesis in renal cell carcinoma through regulation of the NF‑κB signaling pathway., PMID:39091412
Identifying novel proteins for migraine by integrating proteomes from blood and CSF with genome-wide association data., PMID:38898596
Uncovering novel drug targets for bipolar disorder: a Mendelian randomization analysis of brain, cerebrospinal fluid, and plasma proteomes., PMID:38720515
Longitudinal Fluctuations in Protein Concentrations and Higher-Order Structures in the Plasma Proteome of Kidney Failure Patients Subjected to a Kidney Transplant., PMID:38701233
Proteome-Wide Mendelian Randomization and Colocalization Analysis Identify Therapeutic Targets for Knee and Hip Osteoarthritis., PMID:38540773
Screening Plasma Proteins for the Putative Drug Targets for Carpal Tunnel Syndrome., PMID:37878141
Systematic review of type 1 diabetes biomarkers reveals regulation in circulating proteins related to complement, lipid metabolism, and immune response., PMID:37735622
Identification of novel urine proteomic biomarkers for high stamina in high-altitude adaptation., PMID:37250129
Significance of an altered lncRNA landscape in schizophrenia and cognition: clues from a case-control association study., PMID:37009928
Identification of the Characteristic Genes and their Roles in Lung Adenocarcinoma Lymph Node Metastasis through Machine Learning Algorithm., PMID:36277017
Lysine demethylase 5C epigenetically reduces transcription of ITIH1 that results in augmented progression of liver hepatocellular carcinoma., PMID:35080113
Differential Brain and Cerebrospinal Fluid Proteomic Responses to Acute Prenatal Endotoxin Exposure., PMID:35064541
Capacitive interdigitated system of high osteoinductive/conductive performance for personalized acting-sensing implants., PMID:34815414
A serum proteome signature to predict mortality in severe COVID-19 patients., PMID:34226277
A Comparative Analysis of the Lipoprotein(a) and Low-Density Lipoprotein Proteomic Profiles Combining Mass Spectrometry and Mendelian Randomization., PMID:34027348
A clinical model including protein biomarkers predicts radiographic knee osteoarthritis: a prospective study using data from the Osteoarthritis Initiative., PMID:33933586
Pan-cancer analysis identifies ITIH1 as a novel prognostic indicator for hepatocellular carcinoma., PMID:33744857
ECM Characterization Reveals a Massive Activation of Acute Phase Response during FSGS., PMID:32197499
Novel genetic susceptibility loci identified by family based whole exome sequencing in Han Chinese schizophrenia patients., PMID:32066673
Revelation of Proteomic Indicators for Colorectal Cancer in Initial Stages of Development., PMID:32023884
Overproduction of inter-α-trypsin inhibitor heavy chain 1 after loss of Gα13 in liver exacerbates systemic insulin resistance in mice., PMID:31597753
Association of MAD1L1 polymorphism (rs871925) with prenatal famine exposure and schizophrenia in a Chinese population: A case-control study., PMID:31498969
Predictive modeling of therapeutic response to chondroitin sulfate/glucosamine hydrochloride in knee osteoarthritis., PMID:31489155
Inter-α-inhibitor deficiency in the mouse is associated with alterations in anxiety-like behavior, exploration and social approach., PMID:29987918
Discovery of circulating proteins associated to knee radiographic osteoarthritis., PMID:28273936
iTRAQ-Based Proteomics Identification of Serum Biomarkers of Two Chronic Hepatitis B Subtypes Diagnosed by Traditional Chinese Medicine., PMID:28025641
Identification of novel serum peptide biomarkers for high-altitude adaptation: a comparative approach., PMID:27150491
Isolation of a Genomic Region Affecting Most Components of Metabolic Syndrome in a Chromosome-16 Congenic Rat Model., PMID:27031336
Proteomic analysis of preovulatory follicular fluid reveals differentially abundant proteins in less fertile dairy cows., PMID:27003612
Expression and localization of Inter-alpha Inhibitors in rodent brain., PMID:26964679
Investigation of manic and euthymic episodes identifies state- and trait-specific gene expression and STAB1 as a new candidate gene for bipolar disorder., PMID:25136889
[Effect of Hanfangji compound on proliferation of hepatic stellate cells and expressions of TTR, ITIH1 and SERPINF2]., PMID:24422404
Hyaluronan and hyaluronan binding proteins are normal components of mouse pancreatic islets and are differentially expressed by islet endocrine cell types., PMID:22821669
Involvement of ITIH5, a candidate gene for congenital uterovaginal aplasia (Mayer-Rokitansky-Küster-Hauser syndrome), in female genital tract development., PMID:23539898
Sequencing and gene expression of the porcine ITIH SSC13 cluster and its effect on litter size in an Iberian × Meishan F2 population., PMID:21992966
Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4., PMID:21926972
Frequent expression loss of Inter-alpha-trypsin inhibitor heavy chain (ITIH) genes in multiple human solid tumors: a systematic expression analysis., PMID:18226209
Expression of inter-alpha-trypsin inhibitor heavy chains in endometrium of cyclic and pregnant gilts., PMID:14611635
Comparative mapping between human chromosome 3 and porcine chromosome 13., PMID:10449918
For research use only. Not for human or drug use.
