Catalog No.
YHD35201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Gln19-Ser201
Predicted molecular weight
23.96 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P19652
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
AGP2, OMD 2, ORM2, Orosomucoid-2, AGP 2, Alpha-1-acid glycoprotein 2
Case Report: Endocrine, immune and disease dynamics in a patient with rheumatoid arthritis during flare and medication change., PMID:40406145
Bile acid regulation of xenobiotic nuclear receptors on the expressions of orosomucoids in the liver., PMID:40327538
Reactive cholangiocyte-derived ORM2 drives a pathogenic modulation of the injured biliary niche through macrophage reprogramming., PMID:40199572
Plasma proteome fingerprint in kidney diseases., PMID:39896931
Deficiency of hepatokine orosomucoid1 aggravates NAFLD progression in mice., PMID:39756714
More than carriers, orosomucoids are key metabolic modulators., PMID:39701917
Quercetin suppresses cell viability in triple-negative breast cancer by targeting ORM2., PMID:39659916
Orm proteins control ceramide synthesis and endocytosis via LCB-mediated Ypk1 regulation., PMID:39490931
Identification of Plasma Protein Biomarkers for Predicting Lung Cancer., PMID:39477293
A Comparison of White and Yellow Seminal Plasma Phosphoproteomes Obtained from Turkey (Meleagris gallopavo) Semen., PMID:39337428
Orosomucoid 2 is an endogenous regulator of neuronal mitochondrial biogenesis and promotes functional recovery post-stroke., PMID:39293585
Intermittent Fasting-Induced Orm2 Promotes Adipose Browning via the GP130/IL23R-p38 Cascade., PMID:39248328
TRIM24 Up-Regulates ORM2 to Alleviate Abnormal Lipid Metabolism, Inflammation, and Oxidative Stress in Mice with Obstructive Sleep Apnea Syndrome and Metabolic Dysfunction-Associated Steatotic Liver Disease., PMID:39168366
The structure of the Orm2-containing serine palmitoyltransferase complex reveals distinct inhibitory potentials of yeast Orm proteins., PMID:39167489
An effective urobilin clearance strategy based on paramagnetic beads facilitates microscale proteomic analysis of urine., PMID:38775334
Simultaneous deletion of ORMDL1 and ORMDL3 proteins disrupts immune cell homeostasis., PMID:38715613
4R-cembranoid suppresses glial cells inflammatory phenotypes and prevents hippocampal neuronal loss in LPS-treated mice., PMID:38656664
A candidate panel of eight urinary proteins shows potential of early diagnosis and risk assessment for diabetic kidney disease in type 1 diabetes., PMID:38574989
The acute phase reactant orosomucoid-2 directly promotes rheumatoid inflammation., PMID:38556552
Orosomucoid 2 upregulation mediates liver injury-induced colorectal cancer liver metastasis by promoting EMT and cell migration., PMID:38475962
Gene Expression Array Analyses Predict Proto-Oncogene Expression During Perineural Invasion in Pancreatic Ductal Adenocarcinoma., PMID:38454277
Orosomucoid 2 as a biomarker of carotid artery atherosclerosis plaque vulnerability through its generation of reactive oxygen species and lipid accumulation in vascular smooth muscle cells., PMID:38447392
The Hepatokine Orosomucoid 2 Mediates Beneficial Metabolic Effects of Bile Acids., PMID:38320268
Collaborative regulation of yeast SPT-Orm2 complex by phosphorylation and ceramide., PMID:38285738
Identification of Potential Drug Targets for Antiplatelet Therapy Specifically Targeting Platelets of Old Individuals through Proteomic Analysis., PMID:38001945
Identification of distinct active pools of yeast serine palmitoyltransferase in sub-compartments of the ER., PMID:37982431
Synaptic Involvement of the Human Amygdala in Parkinson's Disease., PMID:37947401
Orm2 Deficiency Aggravates High-Fat Diet-Induced Obesity through Gut Microbial Dysbiosis and Intestinal Inflammation., PMID:37853937
Orosomucoid proteins limit endoplasmic reticulum stress in plants., PMID:37606093
Mitigation of non-alcoholic steatohepatitis via recombinant Orosomucoid 2, an acute phase protein modulating the Erk1/2-PPARγ-Cd36 pathway., PMID:37355990
Antithrombin, Protein C, and Protein S: Genome and Transcriptome-Wide Association Studies Identify 7 Novel Loci Regulating Plasma Levels., PMID:37128921
Integrated proteome sequencing, bulk RNA sequencing and single-cell RNA sequencing to identify potential biomarkers in different grades of intervertebral disc degeneration., PMID:37009470
Urinary proteome profiles associated with cognitive decline in community elderly residents-A pilot study., PMID:37006491
Deletion of ORM2 Causes Oleic Acid-Induced Growth Defects in Saccharomyces cerevisiae., PMID:36719521
An ERAD-independent role for rhomboid pseudoprotease Dfm1 in mediating sphingolipid homeostasis., PMID:36350249
Diagnostic role of plasma ORM2 in differentiating prostate cancer from benign prostatic hyperplasia., PMID:36198834
Orosomucoid 2 maintains hepatic lipid homeostasis through suppression of de novo lipogenesis., PMID:36050503
DIA-Based Proteomic Analysis of Plasma Protein Profiles in Patients with Severe Acute Pancreatitis., PMID:35745003
Orosomucoid in liver diseases., PMID:34963738
Loggerhead sea turtle Caretta caretta plasma biochemistry and proteome profile modulation during recovery., PMID:34839037
Quantitative Proteomics Analysis of Differentially Expressed Proteins in Serum of Former Uranium Miners by Isobaric Tags for the Relative and Absolute Quantitation., PMID:34819815
Web-based transcriptome analysis determines a sixteen-gene signature and associated drugs on hearing loss patients: A bioinformatics approach., PMID:34758154
[Screening of candidate genes related to low-dose ionizing radiation based on transcriptome-proteome correlation research techniques]., PMID:34727653
Metabolic Analysis of Potential Key Genes Associated with Systemic Lupus Erythematosus Using Liquid Chromatography-Mass Spectrometry., PMID:34646335
Shotgun-based proteomics of extracellular vesicles in Alzheimer's disease reveals biomarkers involved in immunological and coagulation pathways., PMID:34531462
Liver-specific over-expression of Cripto-1 in transgenic mice promotes hepatocyte proliferation and deregulated expression of hepatocarcinogenesis-related genes and signaling pathways., PMID:34517344
Protein and Microbial Biomarkers in Sputum Discern Acute and Latent Tuberculosis in Investigation of Pastoral Ethiopian Cohort., PMID:34150670
A Proteomics-Based Analysis of Blood Biomarkers for the Diagnosis of COPD Acute Exacerbation., PMID:34113087
Orosomucoid can predict baseline peritoneal transport characteristics in peritoneal dialysis patients and reduce peritoneal proteins loss., PMID:33965627
4R-cembranoid confers neuroprotection against LPS-induced hippocampal inflammation in mice., PMID:33874954
For research use only. Not for human or drug use.
