Catalog No.
RHC09701
Species reactivity
Human, Mouse
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
FCM: 1:200-1:400, IF: 1:200-1:1000, IHC: 1:200-1:1000, WB: 1:500-1:2000
Target
WNT1, Proto-oncogene Wnt-1, INT1, Proto-oncogene Int-1 homolog
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P04628
Applications
FCM, IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R2Y80
Single-Cell Transcriptomics Identifies Selective Lineage-Specific Regulation of Genes in Aortic Smooth Muscle Cells in Mice., PMID:39744838
A mechanism of action-reflective, dual cell-based bioassay for determining the bioactivity of sclerostin-neutralizing antibodies., PMID:39389544
Dissociation of Drosophila Evi-Wg Complex Occurs Post Apical Internalization in the Maturing Acidic Endosomes., PMID:39313313
Relationship of posterior peripheral corneal layers and the trabecular meshwork: an immunohistological and anatomical study., PMID:38418206
Vitamin D improves autoimmune diseases by inhibiting Wnt signaling pathway., PMID:38414312
LAPTM4B-mediated hepatocellular carcinoma stem cell proliferation and MDSC migration: implications for HCC progression and sensitivity to PD-L1 monoclonal antibody therapy., PMID:38388484
Porphyromonas gingivalis Lipopolysaccharide Damages Mucosal Barrier to Promote Gastritis-Associated Carcinogenesis., PMID:37943385
Wnt1 induces osteoblastic changes in a well-established osteolytic skeletal metastatic model derived from breast cancer., PMID:37840014
Multi-Targeting DKK1 and LRP6 Prevents Bone Loss and Improves Fracture Resistance in Multiple Myeloma., PMID:36987921
Genotypic and Phenotypic Spectrum and Pathogenesis of WNT1 Variants in a Large Cohort of Patients With OI/Osteoporosis., PMID:36595228
Optimal CCN4 Immunofluorescence for Tissue Microarray., PMID:36370340
Novel 2,6,9-Trisubstituted Purines as Potent CDK Inhibitors Alleviating Trastuzumab-Resistance of HER2-Positive Breast Cancers., PMID:36145262
R-spondin-3 is an oncogenic driver of poorly differentiated invasive breast cancer., PMID:36106661
A WISP1 antibody inhibits MRTF signaling to prevent the progression of established liver fibrosis., PMID:35987202
WNT1-inducible signaling pathway protein 1 regulates kidney inflammation through the NF-κB pathway., PMID:34897418
A transcriptome atlas of the mouse iris at single-cell resolution defines cell types and the genomic response to pupil dilation., PMID:34783308
7-Hydroxycoumarin mitigates the severity of collagen-induced arthritis in rats by inhibiting proliferation and inducing apoptosis of fibroblast-like synoviocytes via suppression of Wnt/β-catenin signaling pathway., PMID:34752968
Therapeutic DNA vaccine encoding CEMIP (KIAA1199) ameliorates kidney fibrosis in obesity through inhibiting the Wnt/β-catenin pathway., PMID:34582938
Inactivation of Wnt/β-catenin/renin angiotensin axis by tumor necrosis factor-alpha inhibitor, infliximab, ameliorates CKD induced in rats., PMID:33482150
E7386, a Selective Inhibitor of the Interaction between β-Catenin and CBP, Exerts Antitumor Activity in Tumor Models with Activated Canonical Wnt Signaling., PMID:33408116
Mechanical Ventilation with Moderate Tidal Volume Exacerbates Extrapulmonary Sepsis-Induced Lung Injury via IL33-WISP1 Signaling Pathway., PMID:33394970
18 Additional Amino Acids of the Signal Peptide of the Bombyx mori Nucleopolyhedrovirus GP64 Activates Immunoglobulin Binding Protein (BiP) Expression by RNA-seq Analysis., PMID:33386938
Activity-dependent endocytosis of Wingless regulates synaptic plasticity in the Drosophila visual system., PMID:33298662
Acetazolamide ameliorates the severity of collagen-induced arthritis in rats: Involvement of inducing synovial apoptosis and inhibiting Wnt/β-catenin pathway., PMID:33278748
The expression and regulation of Wnt1 in tooth movement-initiated mechanotransduction., PMID:33139146
WNT1-inducible-signaling pathway protein 1 regulates the development of kidney fibrosis through the TGF-β1 pathway., PMID:32896021
The Osteocyte as the New Discovery of Therapeutic Options in Rare Bone Diseases., PMID:32733380
Tocilizumab potentiates cisplatin cytotoxicity and targets cancer stem cells in triple-negative breast cancer., PMID:32537818
Wnt1/β-catenin signaling upregulates spinal VGLUT2 expression to control neuropathic pain in mice., PMID:31785260
WNT1-inducible signaling protein-1 mediates TGF-β1-induced renal fibrosis in tubular epithelial cells and unilateral ureteral obstruction mouse models via autophagy., PMID:31512238
Protein C receptor is a therapeutic stem cell target in a distinct group of breast cancers., PMID:31481760
Distinct Neural Sites of GLP-1R Expression Mediate Physiological versus Pharmacological Control of Incretin Action., PMID:31189118
Neuroprotection mediated by the Wnt/Frizzled signaling pathway in early brain injury induced by subarachnoid hemorrhage., PMID:30762013
Anti-LRP5/6 VHHs promote differentiation of Wnt-hypersensitive intestinal stem cells., PMID:30664649
[Progressive pseudorheumatoid dysplasia misdiagnosed as ankylosing spondylitis: a case report]., PMID:30562792
WISP1 mediates lung injury following hepatic ischemia reperfusion dependent on TLR4 in mice., PMID:30522479
Insulin-like growth factor receptor signaling in breast tumor epithelium protects cells from endoplasmic reticulum stress and regulates the tumor microenvironment., PMID:30458886
RNAi-Mediated β-Catenin Inhibition Promotes T Cell Infiltration and Antitumor Activity in Combination with Immune Checkpoint Blockade., PMID:30274786
Mechanism of fibrogenesis in submandibular glands in patients with IgG4-RD., PMID:30251185
Exploring pathways for sustained melanogenesis in facial melasma: an immunofluorescence study., PMID:29846953
Genomic Profile and Pathologic Features of Diffuse Large B-Cell Lymphoma Subtype of Methotrexate-associated Lymphoproliferative Disorder in Rheumatoid Arthritis Patients., PMID:29738359
Direct visualization of the Wntless-induced redistribution of WNT1 in developing chick embryos., PMID:29715461
LGR4 modulates breast cancer initiation, metastasis, and cancer stem cells., PMID:29269400
Silencing of CEMIP suppresses Wnt/β-catenin/Snail signaling transduction and inhibits EMT program of colorectal cancer cells., PMID:29173982
Sox10+ Cells Contribute to Vascular Development in Multiple Organs-Brief Report., PMID:28751573
Osteocyte-specific WNT1 regulates osteoblast function during bone homeostasis., PMID:28628032
Ryk receptors on unmyelinated nerve fibers mediate excitatory synaptic transmission and CCL2 release during neuropathic pain induced by peripheral nerve injury., PMID:28565999
Wnt-1 immunodetection in the regenerating tail of lizard suggests it is involved in the proliferation and distal growth of the blastema., PMID:28233575
Progenitors in Peripheral Nerves Launch Heterotopic Ossification., PMID:28198109
Immunoexpression of Wnt/β-catenin signaling pathway proteins in ameloblastoma and calcifying cystic odontogenic tumor., PMID:28149478
For research use only. Not for human or drug use.
