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Anti-VTN/Vitronectin Antibody (R2Y43)

Catalog #:   RHC05102 Specific References (26) DATASHEET
Host species: Mouse
Isotype: IgG2b
Applications: ELISA, FCM, IHC
Accession: P04004
Overview

Catalog No.

RHC05102

Species reactivity

Human

Host species

Mouse

Isotype

IgG2b

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, IHC: 1:200-1:1000

Target

VN, VTN, Vitronectin, S-protein, Serum-spreading factor, V75

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P04004

Applications

ELISA, FCM, IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R2Y43

Data Image
  • Flow Cytometry
    Flow cytometric analysis of Hela cells using VTN mouse mAb (green) and negative control (red).
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human cervical cancer tissues using VTN mouse mAb with DAB staining.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human liver cancer tissues using VTN mouse mAb with DAB staining.
References

A Novel Recombinant Vitronectin Variant Supports the Expansion and Differentiation of Pluripotent Stem Cells in Defined Animal-Free Workflows., PMID:39329750

Targeting tumor cell-to-macrophage communication by blocking Vtn-C1qbp interaction inhibits tumor progression via enhancing macrophage phagocytosis., PMID:38773982

Macrophage promotes fibroblast activation and kidney fibrosis by assembling a vitronectin-enriched microenvironment., PMID:37441594

Inflammasome Coordinates Senescent Chronic Wound Induced by Thalassophryne nattereri Venom., PMID:37176162

Early immunologic response to mRNA COVID-19 vaccine in patients receiving biologics and/or immunomodulators., PMID:34545370

A replication-competent adenovirus-vectored influenza vaccine induces durable systemic and mucosal immunity., PMID:33529172

Altered Protein Function Caused by AMD-associated Variant rs704 Links Vitronectin to Disease Pathology., PMID:33259607

Vitronectin is Involved in the Morphological Transition of Neurites in Retinoic Acid-Induced Neurogenesis of Neuroblastoma Cell Line Neuro2a., PMID:30937689

Vitronectin from brain pericytes promotes adult forebrain neurogenesis by stimulating CNTF., PMID:30408465

The Streptococcus agalactiae cell wall-anchored protein PbsP mediates adhesion to and invasion of epithelial cells by exploiting the host vitronectin/αv integrin axis., PMID:30030946

Blood vitronectin is a major activator of LIF and IL-6 in the brain through integrin-FAK and uPAR signaling., PMID:29222114

The nuclear receptor NOR-1/NR4A3 regulates the multifunctional glycoprotein vitronectin in human vascular smooth muscle cells., PMID:28666984

Neutrophils releasing IL-17A into NETs are essential to plasma cell differentiation in inflamed tissue dependent on IL-1R., PMID:28010135

Notch increased vitronection adhesion protects myeloma cells from drug induced apoptosis., PMID:26494298

Oral priming with replicating adenovirus serotype 4 followed by subunit H5N1 vaccine boost promotes antibody affinity maturation and expands H5N1 cross-clade neutralization., PMID:25629161

The hierarchical process of differentiation of long-lived antibody-secreting cells is dependent on integrated signals derived from antigen and IL-17A., PMID:24058589

Vitronectin inhibits efferocytosis through interactions with apoptotic cells as well as with macrophages., PMID:23345331

Pre-clinical evaluation of a replication-competent recombinant adenovirus serotype 4 vaccine expressing influenza H5 hemagglutinin., PMID:22363572

Vitronectin dictates intraglomerular fibrinolysis in immune-mediated glomerulonephritis., PMID:21764994

The nuclear localization signal sequence of porcine circovirus type 2 ORF2 enhances intracellular delivery of plasmid DNA., PMID:21305328

Enhanced focal adhesion assembly reflects increased mechanosensation and mechanotransduction at maternal-conceptus interface and uterine wall during ovine pregnancy., PMID:19060096

An enzyme-linked immunosorbent assay for lipovitellin quantification in copepods: a screening tool for endocrine toxicity., PMID:14982375

Contortrostatin, a homodimeric snake venom disintegrin, is a potent inhibitor of osteoclast attachment., PMID:9525341

Differential expression of a truncated form of the urokinase-type plasminogen-activator receptor in normal and tumor thyroid cells., PMID:9515821

Prevalence of rotavirus antibodies in a non-human primate colony., PMID:12160439

Chronic membrane depolarization regulates the level of the guanine nucleotide binding protein Go alpha in cultured neuronal cells., PMID:3131483

Datasheet
$ 220
Product specifications
50 μg 220 100 μg 350

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For research use only. Not for human or drug use.

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Anti-VTN/Vitronectin Antibody (R2Y43) [RHC05102]
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